products in Drug Delivery & Care Solutions: Stabilizer

Roquette

KLEPTOSE® HPB Parenteral Grade Hydroxypropyl Betadex Cyclodextrin

KLEPTOSE® HPB Hydroxypropyl Betadex Cyclodextrin is a modified beta-cyclodextrin parenteral grade material that can be used as an encapsulating agent for Rx injectables. Benefits Improves stabilization of active substances against light and oxidation Enhances solubilization of active pharmaceutical ingredients Features White, amorphous powder Molecule is a torus-shaped ring with a polar hydrophilic outside and an apolar hydrophobic cavity

CP Kelco

XANTURAL® 180 XANTHAN GUM

XANTURAL® 180 XANTHAN GUM product is suitable for use as a pharmaceutical excipient.

ABITEC Corporation

Acconon® MC8-2 EP/NF

Acconon® MC8-2 EP/NF is a mixture of monoesters, diesters, and triesters of glycerol and monoesters and diesters of polyethylene glycols with a mean relative molecular weight between 200-400. It may contain free macrogols. It is manufactured in USA.

CP Kelco

XANTURAL® 11K

Xantural® 11K is an agglomerated xanthan gum product suitable for use as a pharmaceutical excipient.

ABITEC Corporation

Captex® 355

Captex® 355 Medium-Chain Triglycerides originate from vegetable-based sources (typically palm, palm kernel and/or coconut). These food-grade, safe, responsibly sourced ingredients are best known for their functional benefits as emulsifiers, solubilizers and refatting agents for use in a range of markets and applications. They are preferred lipophilic vehicles and solvents for use in various delivery systems, but are most well-known for their numerous health benefits in areas such as weight management, energy, and cognition.ABITEC offers a variety of C8 (caprylic) and C10 (capric) variations to suite your formulation requirements. It is manufactured in USA.

ABITEC Corporation

Captex® 8000

Captex® 8000 Medium-Chain Triglycerides originate from renewable vegetable-based sources (typically palm, palm kernel and/or coconut). Captex 8000 is comprised of pure C8 (caprylic) fatty acid, which are food-grade, safe, and responsibly sourced. They are best known for their functional benefits as emulsifiers, solubilizers and refatting agents for use in personal care and cosmetic applications, but also boast numerous health benefits in human nutrition such as weight management, energy, and cognition. It is manufactured in USA.

PHARMATRANS SANAQ AG

MCC SANAQ® 102

Microcrystalline Cellulose is purified, partially depolymerized cellulose prepared by treating alpha cellulose, obtained as a pulp from fibrous plant material, with mineral acids

ABITEC Corporation

Captex® 300

Captex® 300 Medium-Chain Triglycerides originate from renewable vegetable-based sources (typically palm, palm kernel and/or coconut). This mix of C8 (caprylic) and C10 (capric) fatty acids are food-grade, safe, responsibly sourced ingredients. They are best known for their functional benefits as emulsifiers, solubilizers and refatting agents for use in personal care and cosmetic applications, but also boast numerous health benefits in areas such as weight management, energy, and cognition. This product contains about 70% C8 and 30% C10. It is manufactured in USA.

Jungbunzlauer Suisse AG

Jungbunzlauer Suisse AG Tricalcium Citrate (TCC)

Jungbunzlauer Suisse AG Tricalcium Citrate (TCC) meets the requirements of the US Pharmacopeia (USP), the Food Chemicals Codex (FCC), and the Commission Regulation (EU) No. 231/2012 always in their latest versions. In some countries such as USA, tricalcium citrate is simply denominated calcium citrate. It is produced by complete neutralization of citric acid with a high purity calcium source such as calcium hydroxide or calcium carbonate. With its high calcium content of 21%, tricalcium citrate is the most economic calcium salt among the commonly used organic calcium salts. Tricalcium citrate is supplied as a white, odorless, crystalline powder or fine powder. It is slightly soluble in water and freely soluble in diluted hydrochloric acid. In contrary to other salts, tricalcium citrate is better soluble at lower temperatures (so-called "inverse solubility"). It is practically insoluble in alcohol. During heat treatment, it is less reactive than other calcium salts due to its inverse solubility. With regard to its significantly better bioavailability, tricalcium citrate is preferred over inorganic calcium sources such as calcium carbonate or calcium phosphate.

Stearinerie Dubois

DUBCARE SPG

Dubcare SPG is used as a stabilizer and could be associated with our Dubcare GMS.

Jost Chemical Co.

Jost Chemical Co. Sodium Acetate Trihydrate USP/EP Granular

Sodium Acetate Trihydrate can be used in pharmaceuticals. Sodium Acetate Trihydrate USP/EP Granulated is a White or colorless granulated product.

CP Kelco

MAJOL® 25000S

MAJOL® 25000S is a highly purified Sodium Carboxymethylcellulose. It is based on sustainably sourced cellulose.

Nippon Soda Company

CELNY SL

CELNY SL is a water soluble, non-ionic derivative of cellulose, an abundant and natural polysaccharide found in all plants. CELNY™ brand is a high quality grade of HPC for food and nutraceutical use. CELNY is available in a wide range of viscosities and particle sizes to suit your application needs. It is food use approved globally, non-GMO, non-dairy, gluten and common allergen free. CELNY HPC applications include tablet binder, film forming agent, and stabilizer.

NKY Pharma

KoVidone® K90

KoVidone® K90 are an essential ingredient to formulating highly effective pharmaceutical products. The polymers are produced in a state of the art manufacturing facility operating under full cGMP compliance. In addition, all physical handling and packaging of powders is conducted in class-D clean rooms with specific attention placed on reducing the risk of any potential particulate/foreign matter contamination. KoVidone® K series products possess excellent binding, film-forming, dispersing and thickening properties and are widely used.

Cyclolab

Cyclolab Alpha-cyclodextrin

Cyclolab Alpha-cyclodextrin is a hexasaccharide derived from glucose. It is related to the β- (beta) and γ- (gamma) cyclodextrins, which contain seven and eight glucose units, respectively. All cyclodextrins are white, water-soluble solids with minimal toxicity.

Cyclolab

Cyclolab Beta-cyclodextrin

Cyclolab Beta-cyclodextrin is made of homogeneous cyclic α1,4-linked D-glucopyranose units in a seven member ring. Forms clathrates and suitable for use with dansyl chloride to form water-soluble complexes for fluorescent labeling of proteins.

Roquette

KLEPTOSE® HPB Biopharma Hydroxypropyl Betadex Cyclodextrin

KLEPTOSE® HPB Biopharma Hydroxypropyl Betadex Cyclodextrin is a low endotoxin grade materials that provides protein stabilization for biopharmaceutical downstream applications. With a hydrophobic internal cavity and hydrophilic exterior, KLEPTOSE® HPB BioPharma can encapsulate molecules, forming inclusion complexes where lipophilic compounds are non-covalently bound within the cavity. It is suitable for use in biopharmaceutical manufacturing and as an excipient for injectable dosage forms. Benefits Unique ability to encapsulate and shield water insoluble materials can be utilized to shield exposed hydrophobic residues on aggregation-prone proteins, thereby modulating protein aggregation Shows promise as a multifunctional excipient suitable for biopharma applications Can serve as a tool to synergistically complement biotherapeutic formulations Multicompendial material (EP, USP, JP) Features Starch derivative Cyclic oligosaccharide with a bucket-like structure

Roquette

KLEPTOSE® Linecaps 17 Pea Maltodextrin Cyclodextrin - Pharma

KLEPTOSE® LINECAPS Pea Maltodextrin Cyclodextrin can be used as a solubilizer, stabilizer and taste-making agent in pharma oral dosage applications. Applications Swallowable, chewable and effervescent tablets Lozenges Hard and soft capsules Orally dissolving films Blends Granules Pellets premix Medicated confectionery Syrups Suspensions Liquids Cream Paste Semi-solids

Roquette

KLEPTOSE® HPB Oral Grade Hydroxypropyl Betadex Cyclodextrin - Pharma

KLEPTOSE® HPB Oral Grade is a solubilizer and stabilizer for pharmaceutical and nutraceutical oral dosage applications. Applications Swallowable, chewable and effervescent tablets Lozenges Hard and soft capsules Orally dissolving films Blends Granules Pellets premix Medicated confectionary Syrups Suspensions Liquids Cream Paste Semi-solids Benefits Improves the solubility of poorly soluble compounds Can be used for taste masking of bitter or unpleasant active ingredients

BTC Europe GmbH

Kollidon® CL-SF

Kollidon® CL-SF is a synthetic polyvinyl pyrrolidone copolymer, serving various functions in pharmaceuticals and nutraceuticals. As a versatile ingredient, it acts as a disintegrant, film former, matrix-forming agent, solubilizer, stabilizer, and viscosity modifier. Its applications span drug delivery and care solutions in healthcare and pharma, including oral formulations. In the food and nutrition sector, it contributes to nutrition and well-being through nutraceuticals and supplements. Available in powder and solid forms, Kollidon® CL-SF offers a reliable solution for diverse pharmaceutical and nutraceutical technologies.

BTC Europe GmbH

Kollidon® CL

Kollidon® CL, available in powder and solid form, is a versatile product with multiple functions, including solubilizer, film former, matrix-forming agent, viscosity modifier, disintegrant, and stabilizer. Positioned in both the food and nutrition and healthcare and pharma markets, it caters to oral drug delivery and care solutions. It is available in various dosage forms, like capsules, granules, pellets, and tablets. The product boasts several labeling claims, including being melamine-free, phthalates-free, kosher, sustainable, and more.

BTC Europe GmbH

Kollidon® CL-F

Kollidon® CL-F is available in powder and solid forms, serves as a solubilizer, film former, matrix-forming agent, viscosity modifier, disintegrant, and stabilizer. Positioned in both the food and nutrition and healthcare and pharma markets, it caters to oral drug delivery and care solutions. Suitable for multiple dosage forms, including capsules, granules, pellets, and tablets. The product is characterized by various labeling claims, such as being kosher, sustainable, melamine-free, and more. Manufacturing technologies include direct compression and wet granulation.

BTC Europe GmbH

Kollidon® CL-M Origin Germany

Kollidon® CL-M Origin Germany, a polyvinyl pyrrolidone copolymer of German origin, is a versatile ingredient in pharmaceutical and nutraceutical applications. Derived synthetically, it serves multiple functions, including disintegration, film formation, matrix formation, solubilization, stabilization, and viscosity modification. In powder or solid form, it finds application in healthcare and pharma for drug delivery and care solutions, particularly in oral formulations. Additionally, it contributes to nutrition and well-being in the food and nutrition sector, playing a crucial role in nutraceuticals and supplements.

BTC Europe GmbH

Kollidon® VA 64 Fine

Kollidon® VA 64 Fine, a copovidone-based product, serves diverse functions in pharmaceuticals and nutraceuticals. As an anti-crystallizing agent, binder, dispersing agent, filler, film former, matrix forming agent, and moisture barrier coating, it plays a pivotal role in drug delivery and care solutions. Its applications extend to oral and topical healthcare formulations, as well as nutrition and well-being products in the food and nutrition industry. With a versatile physical form available as both powder and solid, Kollidon® VA 64 Fine embodies essential technologies for achieving optimal performance in pharmaceuticals and nutraceuticals.

BTC Europe GmbH

Kollidon® 90 F

Kollidon® 90 F is a versatile polyvinylpyrrolidone (PVP) known for its role as a binder and stabilizer in pharmaceuticals and nutraceuticals. In powder form, it excels in healthcare and pharma applications, particularly in drug delivery and care solutions, both oral and topical. With a strong presence in pharmaceutical technologies, Kollidon® 90 F offers reliable performance, making it a preferred choice for formulators seeking effective binding and stabilizing capabilities

BTC Europe GmbH

Kollidon® 17 PF

Kollidon® 17 PF, a polyvinylpyrrolidone (PVP) belonging to pharmaceutical and nutraceutical technologies, serves as an anti-crystallizing agent, dispersant, solubilizer, solvent, and stabilizer. This powder form excels in healthcare and pharmaceutical applications, specifically in drug delivery and care solutions for ophthalmic and parenteral uses. With its versatile properties, Kollidon® 17 PF ensures efficient performance in preventing crystallization, dispersing substances, enhancing solubility, acting as a solvent, and providing stabilization, making it an invaluable component in pharmaceutical formulations.

BTC Europe GmbH

Kolliphor® P 407 Geismar

Kolliphor® P 407 Geismar, a poloxamer 407, serves as a versatile pharmaceutical-grade ingredient. Functioning as a dispersant, gelling agent, lubricant, plasticizer, solubilizer, stabilizer, and wetting agent, it finds application in drug delivery and care solutions. Its powdered form makes it adaptable for oral and topical use, catering to diverse pharmaceutical and nutraceutical needs. This poloxamer 407 variant is a crucial component in the healthcare and pharmaceutical industries, contributing to the development of effective formulations.

BTC Europe GmbH

Kollidon® 25

Kollidon® 25, in powder form, functions as a binder and stabilizer in the healthcare and pharma markets. Tailored for drug delivery and care solutions, both oral and topical, it supports various dosage forms, including capsules, granules, suspensions, and tablets. Manufacturing technologies include direct compression and wet granulation.

BTC Europe GmbH

Kollidon® 30 LP

Kollidon® 30 LP, presented as a powder, serves as a binder and stabilizer. Positioned in the healthcare and pharma markets, it finds application in oral and topical drug delivery and care solutions. Suitable for various dosage forms such as capsules, granules, suspensions, and tablets, with manufacturing technologies including direct compression and wet granulation.

BTC Europe GmbH

Kolliphor® PS 20

Kolliphor® PS 20, a versatile polysorbate, excels as an emulsifier, surfactant, solubilizer, stabilizer, and solvent in pharmaceuticals and nutraceutical technologies. Its liquid form finds application in healthcare and pharma for drug delivery and care solutions, both orally and topically. With its nonionic surfactant properties, Kolliphor® PS 20 ensures efficient emulsification and stabilization, contributing to the success of diverse formulations. This polysorbate 20 variant stands as a key ingredient for industries seeking reliable and effective solutions in the realm of pharmaceuticals and nutraceuticals.

BTC Europe GmbH

Kolliwax® S

Kolliwax® S is a white to slightly yellowish waxy substance derived from natural resources, namely coconut oil, palm kernel oil, and/or palm stearine. Comprised of stearic acid 50, it serves as co-emulsifiers and consistency factors in topical pharmaceutical applications. Moreover, it has the potential to function as excipients in solid oral dosage forms, for instance, as matrix formers and lubricants. Its functions include acting as a co-emulsifier, stabilizer, and lubricant. This versatile substance is applicable in various dosage forms, such as creams, ointments, gels, and lotions.

BTC Europe GmbH

Kolliphor® P 338 Geismar

Kolliphor® P 338 Geismar is a versatile powder with the chemical name poloxamer 338. As a dispersant, gelling agent, lubricant, plasticizer, solubilizer, stabilizer, and wetting agent, it finds applications in pharmaceuticals and nutraceuticals. Specifically designed for the healthcare and pharma industries, it excels in drug delivery and care solutions, both oral and topical. Its physical form as a powder ensures ease of handling. With cutting-edge technologies and a focus on enhancing performance, Kolliphor® P 338 Geismar stands out as a reliable choice for various applications in the medical field.

BTC Europe GmbH

Soluplus®

Soluplus® is a graft copolymer comprised of polyvinyl caprolactam, polyvinyl acetate, and polyethylene glycol. It presents as free-flowing granules, ranging from white to slightly yellowish, accompanied by a faint characteristic odor. Designed specifically for solid solutions, this polymeric solubilizer boasts an amphiphilic chemical structure. Its functionalities encompass roles as a bioavailability enhancer, stabilizer, matrix-forming agent, anti-crystallizing agent, film former, filler, and solubilizer. Soluplus® finds application in various forms, including capsules, dispersions, transdermal patches, and tablets. The product adheres to sustainable practices and holds certifications such as China DMF, US DMF, and cGMP compliance.

BTC Europe GmbH

Kolliphor® P 188 Geismar

Kolliphor® P 188 Geismar, a versatile chemical compound also known as poloxamer 188, serves a pivotal role in pharmaceutical and nutraceutical technologies. As a foaming agent, dispersant, gelling agent, lubricant, plasticizer, solubilizer, stabilizer, wetting agent, and emulsifier, it finds application in healthcare and pharma for drug delivery and care solutions. Specifically designed for oral and topical use, Kolliphor® P 188 Geismar ensures optimal performance in diverse pharmaceutical formulations, contributing to the efficacy and reliability of drug delivery systems.

BTC Europe GmbH

Kollidon® 12 PF

Kollidon® 12 PF is available in powder form, serves as an anti-crystallizing agent, dispersant, solubilizer, solvent, and stabilizer. Positioned in the healthcare and pharma markets, it is suitable for injectables and carries the labeling claim of being pyrogen-free. Particularly applicable in ophthalmic and parenteral drug delivery and care solutions.

BTC Europe GmbH

Kollisolv® PG

Kollisolv® PG, a versatile liquid, features propylene glycol, serving as a preservative, emollient, carrier, plasticizer, solvent, stabilizer, and humectant. Tailored for pharmaceuticals and nutraceuticals, it excels in healthcare and pharma applications such as drug delivery and care solutions, both oral and topical. Boasting its efficacy in various roles, Kollisolv® PG stands as a key component in enhancing formulations within the pharmaceutical and nutraceuticals industry.