products in Healthcare & Pharma: Tablets

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Jungbunzlauer Suisse AG banner
Jungbunzlauer Suisse AG logo

Jungbunzlauer Suisse AG

Jungbunzlauer Suisse AG Tricalcium Citrate (TCC)

INCI Name: Calcium Citrate
Ingredient Name: Citric Acid
Functions: Mineral Source, Buffers & pH Stabilizer, Diluent
Dosage Form: Syrups, Suspension, Emulsions
Synonyms: Calcium citrate tetrahydrate, Tricalcium dicitrate tetrahydrate

Jungbunzlauer Suisse AG Tricalcium Citrate (TCC) meets the requirements of the US Pharmacopeia (USP), the Food Chemicals Codex (FCC), and the Commission Regulation (EU) No. 231/2012 always in their latest versions. In some countries such as USA, tricalcium citrate is simply denominated calcium citrate. It is produced by complete neutralization of citric acid with a high purity calcium source such as calcium hydroxide or calcium carbonate. With its high calcium content of 21%, tricalcium citrate is the most economic calcium salt among the commonly used organic calcium salts. Tricalcium citrate is supplied as a white, odorless, crystalline powder or fine powder. It is slightly soluble in water and freely soluble in diluted hydrochloric acid. In contrary to other salts, tricalcium citrate is better soluble at lower temperatures (so-called "inverse solubility"). It is practically insoluble in alcohol. During heat treatment, it is less reactive than other calcium salts due to its inverse solubility. With regard to its significantly better bioavailability, tricalcium citrate is preferred over inorganic calcium sources such as calcium carbonate or calcium phosphate.

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Jungbunzlauer Suisse AG

Jungbunzlauer Suisse AG Trisodium Citrate Anhydrous

INCI Name: Potassium Citrate
Chemical Name: Citric Acid Trisodium Salt
CAS Number: 68-04-2
Functions: Buffers & pH Stabilizer, Mineral Source, Supplement
Chemical Family: Organic Salts
Synonyms: Trisodium Citrate, Trisodium Citrate 

Jungbunzlauer Suisse AG Trisodium Citrate Anhydrous is supplied in accordance with the current requirements of the United States Pharmacopeia (USP), the Food Chemicals Codex (FCC), and the Commission Regulation (EU) No. 231/2012. It is produced by complete neutralization of citric acid with high purity sodium hydroxide or carbonate and subsequent crystallization and dehydration. The common hydrate form, trisodium citrate dihydrate, is widely used in foods, beverages and various technical applications mainly as buffering, sequestering or emulsifying agent. Jungbunzlauer trisodium citrate anhydrous is manufactured from trisodium citrate dihydrate. Water molecules of the dihydrate crystals are removed by a patented process without destroying the original crystal matrix. The resulting crystals have a porous matrix that can be used as a carrier for inorganic and/or organic substances like perfumes and surfactants. Due to its low water content trisodium citrate anhydrous does not add water to the formulation. It has even the excellent ability to take up surplus water from moisture sensitive formulations thus providing better shelf life to the end product. Therefore, trisodium citrate anhydrous finds its particular uses in water sensitive formulations like instant drinks as well as tablets and powders in pharmaceuticals and detergents. Trisodium citrate anhydrous occurs as white, granular crystals or as white, crystalline powder. It is freely soluble in water and practically insoluble in ethanol (96 %). It is a non-toxic, neutral salt with low reactivity. It is chemically stable if stored at ambient temperatures. Trisodium citrate anhydrous is fully biodegradable and can be disposed of with regular waste or sewage.

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