Shin-Etsu Pharma, Nutra and Food
L-HPC LH-32
Chemical Name: Low-Substituted Hydroxypropyl Cellulose
Manufacturing Technology: Tablet Coating, Wet Granulation, Direct Compression
Functions: Disintegrant, Binder
Labeling Claims: Non-GMO, TSE-free, Allergen-free
Certifications & Compliance: National Formulary (NF), DMF Type IV, European Pharmacopeia (Ph. Eur.)
L-HPC (low-substituted hydroxypropyl cellulose NF, JP, EP) This dual functioning excipient acts as both a disintegrant and binder. It is not the same as HPC. L-HPC is insoluble in water. It is an effective disintegrant due to its swelling action in water. Because is has good compressibility, it functions as a dry binder.L-HPC benefits are:Enhanced stability because it is non-ionic and has low water activityIt is peroxide free and provides excellent compatibility for oxygen sensitive APIsImproved disintegrationA variety of grades are available depending on the application. L-HPC LH-32 is suitable for wet granulation, pellet extrusion and layering.