These functional lipid excipients act as solubilizers and emulsifiers in oral drug delivery systems. CAPMUL excipients are recognized as the ideal starting point when formulating BCS Class II & IV (poorly water soluble) and BCS Class III & IV (poorly permeable) molecules. Lipid-based drug delivery systems may be formulated as liquid or semi-solid formulations for oral dosage forms. It is manufactured in USA.

Chemical Name: Glyceryl Monocaprylate

Functions: Binder, Bioavailability Enhancer, Controlled Release Agent, Emulsifier, Encapsulant, Penetration Enhancer, Solubilizer

Dosage Form: Capsules, Creams, Injectables, Lotions, Ointments, Tablets

Labeling Claims: Aflatoxin-free, BSE-free, CMR Substances-free, Clean Label, Non-GMO, Polychlorinated Biphenyls (PCB)-free, TSE-free, Vegan

Certifications & Compliance: BRC Certified, FDA Compliant, GFSI Certified, GMP, Generally Recognized As Safe (GRAS), Hazard Analysis Critical Control Point (HACCP), ISO 45001, ISO 9001

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Knowde Enhanced TDS

Identification & Functionality

CAS No.
93906-96-8

Features & Benefits

Product Highlights

Processing Aids

  • Direct-compression, free-fraction tablet lubricants which reduce ejection force but allow for faster disintegration times than surface spreading lubricants
  • Soft gel lubricants which allow for less washing and ease of capsule printing
  • Binder excipients for hot melt granulation and extrusion

Emulsification

  • Functional lipids for primary and secondary emulsification of actives
  • Emulsifiers and surfactants for the formulation of self-emulsifying drug delivery systems (SEDDS)

Lipid Nanoparticle Delivery Systems

  • Functional lipids for the development of solid lipid nanoparticles and nanostructured lipids

Permeation Enhancement

  • Functional lipids which can increase the permeation of BCS Class III and BCS Class IV actives
  • Increase permeation of polar molecules with functional groups which are ionized at biological pH
  • Increase permeation of actives affected by PGP mediated efflux

Controlled Release

  • Formulation of both matrix and encapsulated controlled release
  • Formulation of controlled release multi-particulates for use in tablet and capsule formulations
  • Directly-compressed matrix controlled release tablet formulations

Encapsulation

  • Formulation of functional multi-particulates
  • Use in both matrix and encapsulated multi-particulates
  • Employ in both congealing and molten fluid bed unit operations

Applications & Uses

Manufacturing Technology
Applications
  • Solubilization

Properties

Physical Form
Typical Properties
ValueUnitsTest Method / Conditions
CBD Solubility (Visual)40%w/w
Solubilization
  • Increase the solubility of BCS Class II and BCS Class IV actives
  • Increase the bioavailability of poorly water-soluble actives
  • Both single lipid and self-emulsifying drug delivery system (SEDDS) formulations of poorly water soluble APIs

Regulatory & Compliance

Regulatory Status

EP, USP/NF

Packaging & Availability

Packaging Type