Capmul® PG-12 EP/NF

1 of 31 products in this brand
Capmul® PG-12 EP/NF is a propylene glycol monoester of lauric acid. It is an excellent solubilizer for many complex poorly soluble drug compounds. Capmul® PG-12 EP/NF is used primarily as a carrier in soft and hard gelatin capsules, a penetration enhancer in transdermal drug delivery systems, and a secondary emulsifier in microemulsions. It is manufactured in USA.

Chemical Name: Propylene Glycol Monolaurate

CAS Number: 27194-74-7

Functions: Bioavailability Enhancer, Carrier, Emulsifier, Penetration Enhancer, Solubilizer

Dosage Form: Capsules, Creams, Lotions, Ointments, Tablets

Labeling Claims: Aflatoxin-free, Allergen-free, BSE-free, CMR Substances-free, Kosher, Mycotoxins-free, Non-GMO, Polychlorinated Biphenyls (PCB)-free, TSE-free, Vegan

Certifications & Compliance: BRC Certified, European Pharmacopeia (Ph. Eur.), FDA Compliant, GFSI Certified, GMP, Generally Recognized As Safe (GRAS), Hazard Analysis Critical Control Point (HACCP), ISO 14001, ISO 45001, ISO 9001, Kosher, National Formulary (NF), The Food Allergen Labeling & Consumer Protection Act of 2004 (FALCPA), United States Pharmacopeia (USP), Vegan

Synonyms: Acaritouch, Atlas G 3851, Atlas G 917, Capmul PG 12, E2580, Emalex PGML, Emcol PL 50, G 917, PGML, PL 100, Propylene Glycol Monododecanoate, Rikemal PL 100

Technical Data Sheet

Knowde Enhanced TDS

Identification & Functionality

CAS No.
27194-74-7
EC No.
248-315-4

Features & Benefits

Applications & Uses

Pharmaceutical and Nutritional Applications
  • Solubilizer
  • Carrier
  • Emulsifier
  • Penetration enhancer for transdermal applications
Applications
  • Permeation Enhancement
  • Solubilization
  • Emulsification

Properties

Physical Form
Appearance
Clear oily liquid colorless or slightly yellow
Fatty Acid Composition
ValueUnitsTest Method / Conditions
C10max. 2.0%EP / NF
C12min. 95%EP / NF
C14max. 3.0%EP / NF
C16max. 1.0%EP / NF
C8max. 0.5%EP / NF
Nutritional Information (per 100 gm)
ValueUnitsTest Method / Conditions
Added Sugars†0g
Calcium0mg
Calories / Energy770Calories
Calories from Fat666Calories
Carbohydrate26g
Cholesterol0mg
Dietary Fiber**0g
Insoluble Fiber0g
Iron0mg
Monounsaturated Fat0g
Other Carbohydrate‡26g
Polyunsaturated Fat0g
Potassium0mg
Protein0g
Saturated Fat74g
Sodium0mg
Soluble Fiber0g
Sugar Alcohols0g
Total Fat74g
Total Sugars (sum of all mono- and disaccharides)0g
Trans Fat0g
Vitamin A0μg RAE
Vitamin C0mg
Vitamin D0μg
Vitamin E (as alpha-tocopherols)0mg
Specifications
ValueUnitsTest Method / Conditions
Acid Valuemax. 4.0mg KOH/gEP / 2NF
IdentificationPassEP / NF
Iodine Valuemax. 1cg I2/gEP / NF
Propylene Glycolmax. 1.0%EP / NF
Propylene Glycol Diestersmax. 10.0%EP / NF
Propylene Glycol Mono Estersmin. 90.0%EP / NF
Saponification Value200 - 230mg KOH/gEP / NF
Total Ashmax. 0.1%EP / NF
Water Contentmax. 1.0%EP / NF
Note

* The nutritional information is calculated based on typical composition of the product and the data for individual products may vary from the information. Calculations based on 4, 4, and 9 calories per gram for protein, carbohydrate, and fat, respectively. This material is provided for informational purposes only and is not a specification.

** Dietary Fiber defined as non-digestible carbohydrates (≥ 3 monomeric units) and lignin that are intrinsic and intact in plants, or added (isolated or synthetic) non-digestible carbohydrates (≥ 3 monomeric units) that have been determined by FDA to have a physiological benefit.

† Added Sugars defined as any “sugar” added during the processing of foods including sugars, sugar syrups, naturally occurring sugars isolated from a whole food and concentrated so that sugar is the primary component (e.g. fruit juice concentrates), or other caloric sweeteners.

‡ Other Carbohydrate: *Note: Certain food additive constituents are not reasonably classified as standard nutritional components. In order to distinguish these constituents from the substances commonly understand to be dietary carbohydrates, they are listed in the “Other Carbohydrate” category.

¹EP: European Pharmacopeia
²USP/NF: United States Pharmacopeia/National Formulary

Regulatory & Compliance

Regulatory
  • Complies with the European Pharmacopeia Monograph for Propylene Glycol Monolaurate, Type II
  • Complies with the United States Pharmacopeia/National Formulary Monograph for Propylene Glycol Monolaurate, Type II

 

Food Additive:

  • US: Title 21 CFR 172.856, “Propylene glycol mono- and diesters of fats and fatty acids” approved as food additives for direct addition to food for human consumption.
  • E477, if tested.
  • Japan: Japanese Standards of Food Additives “Propylene glycol esters of fatty acids,” if tested.

Packaging & Availability

Packaging Type
Standard Packaging
  • 400 lb (181.4 kg) drum
  • 50 lb (22.7 kg) jerrican

Storage & Handling

Shelf Life
36 months
Recommended Storage and Handling
  • Retest/requalify 36 months from date of manufacture.
  • Store in tightly closed containers in a cool, dry location and protect from moisture.