Knowde Enhanced TDS
Identification & Functionality
- Active Component
- Ingredient Name
- Ingredients
- Maqui Berry Extract
- Product Families
- Chemical Structure
Features & Benefits
- Benefit Claims (Health)
- Food Ingredients Features
- Product Highlights
Maqui berry is a native berry that grows in the wild forests of Patagonia in Chile and Argentina. This berry has been consumed from ancient times by indigenous people and is by nature extraordinarily rich in many nutrients and powerful flavonoid species known as anthocyanins. A specific category of these flavonoids, known as delphinidins is responsible for the very dark purple color of the berries as well as for several health applications.
- Unique Features
- Restoration of healthy tear fluid generation
- Comfortable and safe alternative to artificial tear drops
- Various product combinations feasible
- Already low doses showed significant positive clinical effects
- Quality Features
- MaquiBright® is manufactured from selected fresh maqui berries under strict GMP conditions. The product is exclusively produced by Anklam Extrakt® in Germany.
- MaquiBright® is a maqui berry extract providing rich purified flavonoids, standardized to bear a minimum of 25 % delphinidins and a minimum of 35 % total anthocyanins.
- MaquiBright® is certified Kosher and Halal.
- MaquiBright® shows clinically proven bioavailability of key components.
Applications & Uses
- Markets
- Food & Nutrition Applications
- Application
- Dry Eyes
- Applications
Market Applications Details References Dry eye symptoms MaquiBright® restores tear fluid generation in people with dry eye symptoms.
Hitoe et al., 2014
Dry eye symptoms MaquiBright® delphinidins quench oxidative stress and hence restore healthy tear fluid production. Nakamura et al., 2014 Dry eye symptoms MaquiBright® supresses photoreceptor cell death by inhibiting production of reactive oxygen species. Tanaka et al., 2013 Dry eye symptoms MaquiBright® significantly enhances tear fluid production and relieves dry-eye related symptoms. Yamashita et al., 2018
Regulatory & Compliance
- Certifications & Compliance
Technical Details & Test Data
- MaquiBright® for a Natural Eye Health Support
Causes of insufficient tear fluid production:- Higher age (> 55 years)
- Female gender
- Intensive use of smart phones, tablets etc.
- Contact lenses
- Cigarette smoke
- Air conditioning
- Pollution
- Certain medications
- Laser surgery
Signs of insufficient tear fluid production:- Redness
- Stinging
- Itching
- Foreign body sensation
- Sensitivity to light
- Blurred vision
- MaquiBright® Mode of Action
Lachrymal Gland Cell
- Efficacy
MaquiBright® has shown significant effects on the increase of tear production and the decrease of bothersome ocular discomforts in clinical studies.
Schirmer’s test tear fluid secretion
n=74 randomized double-blind placebo controlled trial *p-value < 0.05
Participants using MaquiBright® showed an increase of 89 % in tear fluid production after 4 weeks
Dry Eye-Related Quality-of-Life Score questionnaire (DEQS) *p-value < 0.05
Participants using MaquiBright® reported an amelioration of 57 % in bothersome ocular discomforts after 4 weeks
Safety & Health
- Safety Information
Safety investigations have confirmed absence of health risks related to regular consumption of MaquiBright®. In the USA, MaquiBright® has been affirmed as Generally Recognized As Safe (GRAS).