Knowde Enhanced TDS
Identification & Functionality
- Chemical Family
- Chemical Name
- Cleaning Ingredients Functions
- Technologies
- Compositional Breakdown
Applications
- Compositional Breakdown
Chemical Compound Breakdown CAS No EINECS No. DMDM Hydantoin (equilibrium mixture) 6440-58-0 208-293-9 Methylchloroisothiazolinone 55965-84-9 247-500-7 Methylisothiazolinone 55965-84-9 220-239-6 Water 7732-18-5 231-791-2 Typical Active Ingredient Content % DMDM Hydantoin 22% Methyl chloroisothiazolinone 0.42% Methylisothiazolinone 0.14%
Features & Benefits
- Key Attributes
- Aqueous, non-freezing blend
- Stable and synergistic combination
- Colorless liquid preservative
- Ultra-low free formaldehyde (< 0.09 %)
- Broad spectrum efficacy
- Effective against formaldehyde- and isothiazolinone-resistant organisms
- Ease of handling
- Compatible and soluble in virtually all raw materials
Applications & Uses
- Markets
- Applications
- Home Care Applications
- Personal Hygiene Applications
- Use Level
- 0.05 – 0.25%
- Applications
- Shampoo
- Body wash
- Conditioner
- Hand soap non anti-bac
- Makeup remover
- Manual dishwash
- Laundry detergent
- Recommended Use Level
Application Shampoo/Shower Gel/Liquid Hand Soap 0.05–0.1% Fabric Softener 0.03–0.08% Manual Dishwash Liquid 0.05–0.1% Laundry Detergent 0.05–0.15% Recommended use levels are to be understood as general guidelines only. It is the responsibility of the customer to test stability and efficacy in final formulation to ensure Lonzaserve® ID meets their own performance criteria at the chosen use level.
- Formulation Recommendations
Lonzaserve® ID is offered commercially as an aqueous solution to facilitate handling and formulation. Colorless and essentially odorless, it incorporates easily into many formulations.
It is both chemically and physically compatible with many finished products, although it is recommended to avoid use of Lonzaserve® ID in the presence of strong oxidizing and reducing agents, amines and amine derivatives.
Lonzaserve® ID may show some instability at high pH, and is therefore best suitable for formulations of pH 3–9.
Properties
- Physical Form
- Appearance
- Clear
- Soluble in
- Water
Regulatory & Compliance
- Global Regulatory
Europe
- Not permitted for leave-on products
- Maximum use level of 0.0015 % CMI/MI for rinse-off applications
- Max use level of 0.6 % DMDMH
- Lonzaserve® ID: Lonza’s recommended maximum use level is 0.25%
Japan
- Max use level of 0.3 % DMDMH and 0.01 % CMI/MI for rinse-off
- Not permitted for leave-on
- Not allowed for oral hygiene and lip products or in preparations for children under the age of 3
United States
- Max use level of 0.6 % DMDMH and 0.00075 % CMI/MI for leave-on
- Max use level of 0.6 % DMDMH and 0.0015 % CMI/MI for rinse-off
Technical Details & Test Data
- Efficacy
Studies were run using different concentrations of Lonzaserve® ID in various formulations to assess efficacy against various bacteria, yeast and fungi. All samples were inoculated at the beginning of the study, sampled at 7, 14, 21 and 28 days.
Antimicrobial Efficacy – Challenge Tests
The preservative efficacy of Lonzaserve® ID was tested in a surfactant base formulation and in a GMS skin cream. Samples tested displayed sufficient antimicrobial activity to meet the pass criteria.- Light Duty Liquid Formulation (Shampoo/Dishwashing Liquid Base)
- Test Results
Efficacy in a Light Duty Liquid Formulation (Shampoo/Dishwashing Liquid Base)
- Skincare Cream (nonionic Glycerylmonostearate Base)
- Efficacy in a Light Duty Liquid Formulation (Shampoo/Dishwashing Liquid Base)
Ingredients (unpreserved) % wt/wt Sterile DI Water 36.0 Sodium Lauryl Ether Sulfate 35.0 Triethanolamine Lauryl Sulfate 25.0 Cocoamide DEA 3.0 Anhydrous Protein 1.0 Citric acid q.s. (to achieve pH) Total weight 100.0 Final pH 6.5±0.5 Light Duty Liquid Formulation Mix Bacteria Germ Count (cfu/g) / days 0 7 14 21 28 Unpreserved 1.3x10^6 >10^6 >10^6 >10^6 >10^6 Lonzaserve® ID 0.05% 1.3x106 <10 <10 <10 <10 Light Duty Liquid Formulation Mix Bacteria Germ Count (cfu/g) / days 0 7 14 21 28 Unpreserved 1.7x10^5 >10^5 >10^5 >10^5 >10^5 Lonzaserve® ID 0.05% 1.7x10^5 <10 <10 <10 <10 Efficacy in a Skincare Cream (nonionic Glycerylmonostearate Base)
Ingredients (unpreserved) % wt/wt Glyceryl Monostearate 6.00 PEG-20 Glyceryl monostearate 4.00 Cetearyl Alcohol 1.50 Myristyl Propionate 8.00 Glycerin 5.00 Sterile DI water 75.45 NaOH 0.05 Total weight 100.00 Final pH 7.0–7.5 GMS Cream Mix Bacteria Germ Count (cfu/g) / days 0 7 14 21 28 Unpreserved 1.3x10^6 >10^6 >10^6 >10^6 >10^6 Lonzaserve® ID 0.05% 1.7x10^5 <10 <10 <10 <10 GMS Cream Mix Bacteria Germ Count (cfu/g) / days 0 7 14 21 28 Unpreserved 1.7x10^5 >10^5 >10^5 >10^5 >10^5 Lonzaserve® ID 0.05% 1.7x10^5 <10 <10 <10 <10
Packaging & Availability
- Regional Availability