Mikrokill® COS

1 of 2 products in this brand
Mikrokill® COS is a unique, patented combination of three components (Phenoxyethanol, Chlorphenesin and Caprylyl Glycol), which are well accepted in a wide range of personal care products. Phenoxyethanol is a widely used and versatile preservative. Chlorphenesin is a known broad spectrum preservative and Caprylyl Glycol provides biological synergism with moisturizing and wetting capabilities.

INCI Name: Caprylyl Glycol, Chlorphenesin, Phenoxyethanol

Functions: Anti-Microbial Agent, Bacteriostatic Agent, Fungistatic Agent, Preservative

Ingredient Origin: Synthetic

Benefit Claims: Anti-Bacterial, Anti-Fungal, Antimicrobial, Broad pH Stability, Compatibility, Easy To Handle, Easy To Use, Emolliency, Good Wetting Properties, Low Odor, Moisturizing, Preservation, Skin Protection, Versatility

Labeling Claims: Credo Clean Standard, Environmentally Friendly, Natural, Not Tested on Animals, Organic, Sustainable

Certifications & Compliance: EU Compliant, EU Cosmetic Regulation 1223/2009 Compliant, IECIC (China)

Technical Data Sheet
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Knowde Enhanced TDS

Identification & Functionality

Ingredient Origin
Compositional Breakdown

 

Lonza Mikrokill COS Compositional Breakdown

Features & Benefits

Key Attributes
  • Safe and effective antimicrobial
  • Broad spectrum activity on bacteria, yeast and mold
  • Can be used alone or in combination with other preservatives
  • Stable in the usual operating range for Personal Care products (pH 3-8)
  • Compatible in a wide range of skin care, hair care and sun care systems
  • Low odor profile
  • Liquid for ease of use
  • Wide global acceptance
  • Effective across a wide pH range.
  • Can be used in anhydrous systems and sun care systems
  • Liquid for ease of use

Applications & Uses

AP/Deo Applications
Baby Care Applications
Bath & Shower Applications
Personal Hygiene Applications
Wipes, Tissue & Towel Applications
Use Level
0.75-1.5%
Application pH Range
3–8
Formulations

Hair Conditioner (AR5-026)  

 Base Formulation

Lonza Mikrokill COS Formulations - 1

Test Result

Lonza Mikrokill COS Formulations - 2

Frmulations

Hair Conditioner (AR5-024)  

Base Formulation

Lonza Mikrokill COS Formulations - 3

Test Results

Lonza Mikrokill COS Formulations - 4

Formulations

Oil in Water Lotion (KKL9-137) 

Base Formulation

Lonza Mikrokill COS Formulations - 5

Test Results

Lonza Mikrokill COS Formulations - 6

Formulations

Oil in Water Lotion (KKL-9-159) 

Base Formulation

Lonza Mikrokill COS Formulations - 7

Test Results

Lonza Mikrokill COS Formulations - 8

Formulation Recommendations
  • Can be easily added directly to the oil phase of the formulation
    during pre- or post-emulsification < 60°C
  • For highly aqueous systems, co-solvents, coupling agents and/or surfactants may be needed to assist with solubilization. Mix 1:1 with Glycosperse® L-20 or Lonzest® SML-20 and add to finished product
  • Compatible with most personal care ingredients
  • pH: 2–8
Applications
  • Anhydrous
  • Baby care
  • Baby wipes
  • Body Butter
  • Body wash
  • Conditioner
  • Cream
  • Deo/Anti-Perspirant
  • Eye creams/gels
  • Eye shadow
  • Face Lotion
  • Face wipes
  • Facial Cream

 

  • Foundation
  • Hair gel
  • Hand soap (non anti-bac)
  • Lipstick/gloss
  • Lotion
  • Make up remover
  • Mascara
  • Oil in Water
  • Powder
  • Shampoo
  • Suncare
  • Toner
  • Water in Oil

Properties

Physical Form
Odor
Characteristic
Soluble in
Oils

Regulatory & Compliance

Global Regulatory

Europe

  • Approved under Annex V to Regulation EC/1223/2009
  • Max concentration of 1% Phenoxyethanol and 0.3% Chlorphenesin

Japan

  • All ingredients approved (JNCI)
  • Max concentration of 1% Phenoxyethanol and 0.3% Chlorphenesin
  • Not permitted for products coming into contact with mucous membranes

United States

  • All ingredients allowed (CIR/CTFA)
  • Max concentration of 1% Phenoxyethanol and 0.3% Chlorphenesin

General

  • Phenoxyethanol & Chlorphenesin – classified as preservatives
  • Caprylyl Glycol
    •   Officially/legally classified as an emollient
    • Not recognized and classified as a preservative
    • Antimicrobial synergistic activity becoming recognized

Technical Details & Test Data

Efficacy

Studies were run on four formulas using a 0.75% concentration of Mikrokill® COS. The protocol used was a modification of the Cosmetic, Toiletry and Fragrance Association (CTFA) Challenge test using a 3 week re-challenge time period instead of a 4 week period. All samples were inoculated at the beginning of the study, sampled at 24 hours, 7 days, 14 days and 21 days. The samples were diluted in neutralizer and plated quantitatively for viable organisms at all sampling times. After 21 days, all samples were re-inoculated and subjected to a second challenge.

Packaging & Availability

Country Availability
Regional Availability
  • Africa
  • China
  • Europe
  • India
  • Japan
  • Latin America
  • Middle East
  • North America
  • Oceania
  • South East Asia