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Geogard® 221
INCI Name:
Dehydroacetic Acid, Benzyl Alcohol
Functions:
Fungistatic Agent, Preservative, Bacteriostatic Agent
Ingredient Origin:
Synthetic
Benefit Claims:
Broad pH Stability, Anti-Fungal, Preservation, Anti-Bacterial, Compatibility, Cost Effective, Chemical Stability
Labeling Claims:
Environmentally Friendly, Odor-free, Non-GMO, Credo Clean Standard, Organic, Sustainable, Cruelty-Free, Natural, Not Tested on Animals, Clean at Sephora
Certifications & Compliance:
EU Cosmetic Regulation 1223/2009 Compliant, COSMOS, Cruelty-Free, EU Compliant, IECIC (China), ECOCERT, ISO 16128, Soil Association Approved
Geogard® 221 preservative is based on a synergistic blend of 2 active ingredients, dehydroacetic acid (DHA) and benzyl alcohol. The product is recognized by major cosmetic, toiletry and fragrance regulatory authorities worldwide for use in cosmetic and personal care products and formulations. Geogard®221 has a broad spectrum activity, is light in color, essentially odorless and easy to formulate in a diverse range of products.INCI Name: Benzyl Alcohol (CAS: 100-51-6), Dehydroacetic Acid (CAS: 520-45-6) and Aqua (CAS: 7732-18-5)Key Benefits of Geogard® 221:Wide range of global regulatory approvalsBroad spectrum protectionECOCERT/COSMOS compliant, NATRUE certified and Soil Association approvedWide applicability/compatibility with key raw materialsEasy-to-use and compatible with most types of cosmetic formulationsBenefit and Labeling Claims:Benefit ClaimsBroad pH StabilityChemical StabilityCompatibilityCost EffectiveLabeling ClaimsCruelty-FreeEnvironmentally FriendlyNon-GMONot Tested on AnimalsOdor-freeSustainableApplications Include:Personal Care — Beauty & CareBaby CareBath & ShowerColor CosmeticsHair CareSkin Care
Geogard Ultra®
INCI Name:
Sodium Benzoate, Calcium Gluconate, Gluconolactone
Functions:
Preservative Booster, Fungistatic Agent, Preservative, Bacteriostatic Agent
Ingredient Origin:
Natural Origin, Synthetic
Benefit Claims:
Easy Application, Ease of Formulation, Broad pH Stability, Anti-Fungal, Preservation, Moisturizing, Anti-Bacterial, Compatibility, Versatility, Chemical Stability
Labeling Claims:
Clean at Sephora, Naturally Derived, Ulta Beauty's Conscious Beauty, Halal, Environmentally Friendly, Vegan, Non-GMO, Credo Clean Standard, Organic, Sustainable, Cruelty-Free, Natural
Certifications & Compliance:
Halal, EU Cosmetic Regulation 1223/2009 Compliant, COSMOS, EU Compliant, IECIC (China), NaTrue, ECOCERT, ISO 16128, Soil Association Approved, Organic Certified
Geogard Ultra® is a patented, synergistic blend consisting of Gluconolactone (polyhydroxy acid or PHA) and Sodium Benzoate. The synergy between these two ingredients, Gluconolactone and Sodium Benzoate, makes this preservative unique, allowing for its broad spectrum efficacy.Organic acids often require a co-preservative or additional booster to provide an optimal performance, as they are too weak on their own. In this blend, the Gluconolactone works in conjunction with the sodium benzoate to perform as an efficient preservative booster that is also non-GMO. Geogard Ultra®’s Gluconolactone works by slowly releasing Gluconic Acid over time, which helps contribute to the preservation effect.INCI Name: Gluconolactone (CAS: 90-80-2), Sodium Benzoate (CAS: 532-32-1) and Calcium Gluconate (CAS: 299-28-5)Key Benefits of Geogard Ultra®:Wide range of global regulatory acceptanceBroad spectrum activityECOCERT/COSMOS accepted, NATRUE and Soil Association approvedWide applicability/compatibilityEasy to formulateAdded skin moisturization benefitApplications Include:Beauty & CareAP/DeoBaby CareBath & ShowerColor CosmeticsHair CareOral CareSkin CareSun CarePersonal HygieneHand HygieneOther Personal Hygiene ApplicationsWipes, Tissue & TowelLabeling Claims of Geogard Ultra®:Cruelty-FreeEnvironmentally FriendlyHalalNaturalNaturally DerivedNon-GMOOrganicSustainable
Geogard® 111A
INCI Name:
Dehydroacetic Acid
Functions:
Fungistatic Agent, Preservative
Ingredient Origin:
Synthetic
Benefit Claims:
Broad pH Stability, Anti-Fungal, Preservation, Anti-Bacterial, Compatibility, Chemical Stability, Superior Performance
Labeling Claims:
Environmentally Friendly, Vegan, Non-GMO, Credo Clean Standard, Organic, Sustainable, Cruelty-Free, Natural, Not Tested on Animals, Clean at Sephora, Ulta Beauty's Conscious Beauty
Certifications & Compliance:
EU Cosmetic Regulation 1223/2009 Compliant, COSMOS, Cruelty-Free, EU Compliant, IECIC (China), ECOCERT, ISO 16128, Soil Association Approved, Organic Certified
Geogard® 111A offer reliable anti-fungal efficacy at relatively low product use levels. Geogard® 111A is based on dehydroacetic acid (DHA); These preservatives have a wide range of global regulatory acceptance for many personal care and cosmetic applications. Test data of Geogard® 111A to parabens show higher efficacy and substantially better performance in low to neutral pH formulations.
Cosmocil® CQ
INCI Name:
Polyaminopropyl Biguanide
Functions:
Anti-Microbial Agent, Preservative, Bacteriostatic Agent
Ingredient Origin:
Synthetic
Benefit Claims:
Neutral Color, Broad pH Stability, Low Volatility, Sunlight Stability, Preservation, Low Foaming, Anti-Bacterial, Compatibility, Conditioning, Reduces Stickiness, Chemical Stability, Antimicrobial, Tasteless
Labeling Claims:
Ulta Beauty's Conscious Beauty, Halal, Environmentally Friendly, Odor-free, Vegan, Non-GMO, VOC-free, Credo Clean Standard, Organic, Sustainable, Natural
Certifications & Compliance:
Halal, EU Cosmetic Regulation 1223/2009 Compliant, EU Compliant, IECIC (China)
Cosmocil® CQ is a broad spectrum, fast-acting antibacterial. A 20% aqueous solution of poly(hexamethylenebiguanide) hydrochloride, also known as PHMB, Cosmocil® CQ is an effective preservative for personal care formulations, active against a wide range of both Gram-positive and Gram-negative bacteria.
Glydant Plus® Liquid
INCI Name:
Iodopropynyl Butylcarbamate, DMDM Hydantoin
Functions:
Anti-Microbial Agent, Fungistatic Agent, Preservative, Bacteriostatic Agent
Ingredient Origin:
Synthetic
Benefit Claims:
Easy To Handle, Temperature stability, Broad pH Stability, Color Stability, Sunlight Stability, Anti-Fungal, Preservation, Anti-Bacterial, Compatibility, Cost Effective, Low Odor, Easy To Use, Skin Protection
Labeling Claims:
Ulta Beauty's Conscious Beauty, Halal, Environmentally Friendly, Non-GMO, Formaldehyde-free, Organic, Sustainable, Natural
Certifications & Compliance:
Halal, EU Cosmetic Regulation 1223/2009 Compliant, EU Compliant, IECIC (China)
Glydant Plus® Liquid is a synergistic preservation system that combines two well-known and traditional chemistries for personal care. The combination of DMDM Hydantoin and Iodopropynyl Butylcarbamate allow for a dual mode of action, offering broad spectrum efficacy. These chemistries been used in personal care for years. This product contains the same amount of active ingredient as Lonza’s Glydant Plus® but is offered as a liquid form.
Geogard® 111S
INCI Name:
Dehydroacetic Acid, Sodium Dehydroacetate
Functions:
Fungistatic Agent, Preservative
Ingredient Origin:
Synthetic
Benefit Claims:
Broad pH Stability, Anti-Fungal, Preservation, Anti-Bacterial, Compatibility, Chemical Stability
Labeling Claims:
Environmentally Friendly, Vegan, Non-GMO, Credo Clean Standard, Organic, Sustainable, Cruelty-Free, Natural, Not Tested on Animals, Clean at Sephora, Ulta Beauty's Conscious Beauty
Certifications & Compliance:
EU Cosmetic Regulation 1223/2009 Compliant, COSMOS, Cruelty-Free, EU Compliant, IECIC (China), ECOCERT, ISO 16128, Soil Association Approved, Organic Certified
Geogard® 111S offer reliable anti-fungal efficacy at relatively low product use levels. Geogard® 111S is based on dehydroacetic acid (DHA); These preservatives have a wide range of global regulatory acceptance for many personal care and cosmetic applications. Test data of Geogard® 111S to parabens show higher efficacy and substantially better performance in low to neutral pH formulations.
Geogard® ECT
INCI Name:
Benzyl Alcohol, Salicylic Acid, Sorbic Acid
Functions:
Anti-Microbial Agent, Fungistatic Agent, Preservative, Bacteriostatic Agent
Ingredient Origin:
Synthetic
Benefit Claims:
Easy Application, Broad pH Stability, Anti-Fungal, Preservation, Anti-Bacterial, Compatibility, Cost Effective, Versatility, Low Odor, Chemical Stability, Antimicrobial
Labeling Claims:
Environmentally Friendly, Fragrance-free, Odor-free, Vegan, Non-GMO, Credo Clean Standard, Organic, Sustainable, Cruelty-Free, Natural, Not Tested on Animals, Clean at Sephora
Certifications & Compliance:
EU Cosmetic Regulation 1223/2009 Compliant, COSMOS, Cruelty-Free, EU Compliant, IECIC (China), ECOCERT, ISO 16128, Soil Association Approved, Organic Certified
Geogard® ECT is a unique, patented combination of benzyl alcohol, salicylic acid, glycerin and sorbic acid, which are well accepted in a wide range of personal care products. The novel composition of this antimicrobial blend offers a low cost in use as well as broad spectrum protection in a diverse range of products against Gram-positive and Gram-negative bacteria, yeast and molds at wide pH ranges. Geogard® ECT has a wide range of global regulatory acceptance for personal care products.
Glydant® 2000
INCI Name:
DMDM Hydantoin
Functions:
Fungistatic Agent, Preservative, Bacteriostatic Agent
Benefit Claims:
Low Viscosity, Anti-Bacterial, Compatibility, Cost Effective, Broad pH Stability, Anti-Crystallization, Improves Clarity, Color Stability, Anti-Fungal, Preservation
Labeling Claims:
Ulta Beauty's Conscious Beauty, Organic, Halal, Environmentally Friendly, Sustainable, Vegan, Non-GMO, Natural, Formaldehyde-free
Certifications & Compliance:
EU Compliant, IECIC (China), Halal, EU Cosmetic Regulation 1223/2009 Compliant
Glydant® 2000 is a high performance cosmetic and personal care preservative that is an excellent bactericide, mild fungicide. It provides the lowest free formaldehyde available to the industry. This cost-effective preservation system offers color stability in formulations and water-white clarity with no crystallization problems.
Mikrokill® COS
INCI Name:
Chlorphenesin, Caprylyl Glycol, Phenoxyethanol
Functions:
Fungistatic Agent, Preservative, Bacteriostatic Agent, Anti-Microbial Agent
Ingredient Origin:
Synthetic
Benefit Claims:
Easy To Handle, Good Wetting Properties, Broad pH Stability, Anti-Fungal, Preservation, Moisturizing, Anti-Bacterial, Compatibility, Versatility, Emolliency, Low Odor, Antimicrobial, Easy To Use, Skin Protection
Labeling Claims:
Environmentally Friendly, Credo Clean Standard, Organic, Sustainable, Natural, Not Tested on Animals
Certifications & Compliance:
EU Cosmetic Regulation 1223/2009 Compliant, EU Compliant, IECIC (China)
Mikrokill® COS is a unique, patented combination of three components (Phenoxyethanol, Chlorphenesin and Caprylyl Glycol), which are well accepted in a wide range of personal care products. Phenoxyethanol is a widely used and versatile preservative. Chlorphenesin is a known broad spectrum preservative and Caprylyl Glycol provides biological synergism with moisturizing and wetting capabilities.
Isocil® PC
INCI Name:
Methylchloroisothiazolinone, Methylisothiazolinone, DMDM Hydantoin
Functions:
Fungistatic Agent, Preservative, Bacteriostatic Agent
Benefit Claims:
Compatibility, Cost Effective, Anti-Fungal, Preservation, Easy To Use, Skin Protection, Anti-Bacterial
Labeling Claims:
Environmentally Friendly, Sustainable, Natural, Ulta Beauty's Conscious Beauty, Organic
Certifications & Compliance:
EU Cosmetic Regulation 1223/2009 Compliant, EU Compliant, IECIC (China)
Isocil® PC is a combination of two commonly used personal care preservatives, Methyl chloroisothiazolinone and Methylisothiazolinone (MI/CMI). These traditional preservatives have been used for years offering excellent broad spectrum efficacy at low use levels. With the added benefit of a strong safety profile as well as toxicological data, this chemistry is appealing amongst many formulators.
Glycacil® L
INCI Name:
Iodopropynyl Butylcarbamate
Functions:
Preservative, Fungistatic Agent
Benefit Claims:
Easy To Handle, Compatibility, Temperature stability, Broad pH Stability, Conditioning, Anti-Fungal, Thermal Stability, Preservation
Labeling Claims:
Clean at Sephora, Ulta Beauty's Conscious Beauty, Organic, Halal, Environmentally Friendly, Sustainable, Vegan, Non-GMO, Natural
Certifications & Compliance:
EU Compliant, IECIC (China), ISO 16128, Halal, EU Cosmetic Regulation 1223/2009 Compliant
Glycacil® L is a highly-effective fungicide that is very efficient in inhibiting the growth of yeasts and molds. Due to its compatibility with commonly used cosmetic ingredients, Glycacil® L remains fully functional at low concentrations and is very cost effective. In addition to offering stability over wide pH and temperature ranges, it also features safe toxicological and ecological profiles. Available in convenient forms to facilitate handling ease.
Glycacil® 2000
INCI Name:
Iodopropynyl Butylcarbamate
Functions:
Preservative, Fungistatic Agent
Benefit Claims:
Improved Freeze/Thaw Stability, Excellent Flexibility, Easy To Handle, Compatibility, Temperature stability, Broad pH Stability, Conditioning, Anti-Fungal, Thermal Stability, Preservation
Labeling Claims:
Clean at Sephora, Ulta Beauty's Conscious Beauty, Organic, Halal, Environmentally Friendly, Sustainable, Vegan, Non-GMO, Natural
Certifications & Compliance:
EU Compliant, IECIC (China), ISO 16128, Halal, EU Cosmetic Regulation 1223/2009 Compliant
Glycacil® 2000 is a water soluble preservative variant of iodopropynyl butylcarbamate that offers strong efficacy against yeasts and molds. This preservative is globally approved for rinse-off and leave-on products, has a strong safety profile, is temperature stable, and is compatible with commonly used ingredients such as cationic, anionic, nonionic surfactants, emulsifiers and proteins.
Glydant® LTD
INCI Name:
DMDM Hydantoin
Functions:
Anti-Microbial Agent, Preservative, Bacteriostatic Agent
Benefit Claims:
Mild, Anti-Bacterial, Compatibility, Cost Effective, Anti-Fungal, Preservation
Labeling Claims:
Ulta Beauty's Conscious Beauty, Organic, Halal, Environmentally Friendly, Sustainable, Non-GMO, Natural
Certifications & Compliance:
IECIC (China), Halal, EU Cosmetic Regulation 1223/2009 Compliant
Glydant® LTD is a high performance preservative for cosmetics and toiletries that is fully compatible with cationic, anionic or nonionic surfactants, emulsifiers and proteins. Glydant™ LTD has applications in hair care, shaving, lotions, powders, baby products, eye makeup, sun products, creams, and other raw materials.
Spectradyne™
INCI Name:
Chlorhexidine Digluconate
Ingredient Origin:
Synthetic
Functions:
Anti-Microbial Agent, Preservative, Bacteriostatic Agent
Benefit Claims:
Mild, Anti-Bacterial, Non-Sensitizing, Compatibility, Preservation
Labeling Claims:
Clean at Sephora, Ulta Beauty's Conscious Beauty, Organic, Environmentally Friendly, Sustainable, Natural
Certifications & Compliance:
EU Compliant, IECIC (China), EU Cosmetic Regulation 1223/2009 Compliant, United States Pharmacopeia (USP)
Synonyms:
Hibiclens, Peridex
SPECTRADYNE™ is a strong bactericide that can be used in a variety of personal care applications. It is extremely mild to skin and is non- sensitizing. Low use levels are required for an excellent effect in finished formulations.
Arxada Benzethonium Chloride
INCI Name:
Benzethonium Chloride
Ingredient Origin:
Synthetic
Functions:
Anti-Microbial Agent, Preservative, Bacteriostatic Agent
Benefit Claims:
Mild, Anti-Bacterial, Non-Sensitizing, Compatibility, Broad pH Stability, Conditioning, Anti-Fungal, Preservation
Labeling Claims:
Organic, Environmentally Friendly, Sustainable, Odor-free, Natural
Certifications & Compliance:
EU Compliant, IECIC (China), EU Cosmetic Regulation 1223/2009 Compliant
Synonyms:
{2-[2-(4-Diisobutylphenoxy)Ethoxy]Ethyl}Dimethylbenzylammonium Chloride, Benzetonium Chloride, Benzyldimethyl-P-(1,1,3,3-Tetramethylbutyl)Phenoxyethoxy-Ethylammonium Chloride, Benzyldimethyl(2-{2-[4-(1,1,3,3-Tetramethylbutyl)Phenoxy]Ethoxy}Ethyl)Ammonium Chloride, BZT, Diisobutylphenoxyethoxyethyl Dimethyl Benzyl Ammonium Chloride, N,N-Dimethyl-N-(2-{2-[4-(1,1,3,3-Tetramethylbutyl)Phenoxy]Ethoxy}Ethyl)-Benzenemethanaminium Chloride, p-tert-Octylphenoxyethoxyethyldimethylbenzylammonium Chloride
Benzethonium Chloride USP is a reliable and trusted cationic antimicrobial that can also be used as a personal care preservative. Benzethonium Chloride USP offers greater efficacy, mildness, and safety versus competitive chemistries as an active antimicrobial ingredient, coupled with global-acceptance as a fast-acting preservative.
Glydant Plus®
INCI Name:
Iodopropynyl Butylcarbamate, DMDM Hydantoin
Functions:
Fungistatic Agent, Preservative
Ingredient Origin:
Synthetic
Benefit Claims:
Antimicrobial, Skin Protection, Anti-Bacterial, Compatibility, Cost Effective, Heat Stability, Broad pH Stability, Conditioning, Anti-Fungal, Excellent Stability, Low Odor, Preservation
Labeling Claims:
Ulta Beauty's Conscious Beauty, Organic, Halal, Environmentally Friendly, Sustainable, Non-GMO, Natural
Certifications & Compliance:
EU Compliant, IECIC (China), Halal, EU Cosmetic Regulation 1223/2009 Compliant
Glydant Plus® is a synergistic preservation system that combines two well-known and traditional chemistries for personal care. The combination of DMDM Hydantoin and Iodopropynyl Butylcarbamate (IPBC) allow for a dual mode of action, offering broad spectrum efficacy. These chemistries been used in personal care for years and have excellent safety and toxicological data. This product contains twice the amount of active ingredient as LSI’s Glydant Plus® Liquid but is offered as a powder form.
Glydant®
INCI Name:
DMDM Hydantoin
Functions:
Anti-Microbial Agent, Fungistatic Agent, Preservative, Bacteriostatic Agent
Benefit Claims:
Easy To Use, Low Viscosity, Excellent Flexibility, Anti-Bacterial, Compatibility, Cost Effective, Heat Stability, Color Stability, Anti-Fungal, Preservation
Labeling Claims:
Ulta Beauty's Conscious Beauty, Organic, Halal, Environmentally Friendly, Sustainable, Non-GMO, Natural
Certifications & Compliance:
EU Compliant, IECIC (China), Halal, EU Cosmetic Regulation 1223/2009 Compliant
Glydant® is a preservative system that provides excellent bactericide and mild fungicide for product protection. This cost-effective, water soluble system can be easily incorporated into a broad number of personal care products and offers water-white/color stability, heat stability, and compatibility with anionic, nonionic and cationic systems.
Glydant Plus® PC
INCI Name:
Methylchloroisothiazolinone, Methylisothiazolinone, DMDM Hydantoin
Functions:
Fungistatic Agent, Preservative, Bacteriostatic Agent
Benefit Claims:
Skin Protection, Anti-Bacterial, Easy To Handle, Freezing Resistant, Compatibility, Color Stability, Anti-Fungal, Excellent Stability, Preservation, Antimicrobial, pH Neutral
Labeling Claims:
Ulta Beauty's Conscious Beauty, Organic, Environmentally Friendly, Sustainable, Natural, Formaldehyde-free
Certifications & Compliance:
EU Compliant, IECIC (China), EU Cosmetic Regulation 1223/2009 Compliant
Glydant Plus® PC is a synergistic preservative system with dual broad spectrum activity for maximum preservation. It is effective against formaldehyde and isothiazolinone resistant organisms, Gram-positive and Gram-negative bacteria, fungi and yeast over a broad pH range. It is a colorless liquid with a very safe toxicology profile that is compatible for use in most personal care formulations.
NUGEN® R-82G
Chemical Family:
Quaternary Ammonium Compounds
Product Type:
Cleaner, Disinfectant Products, Detergents, Sanitizers
Certifications & Compliance:
BPR Supported, EPA Registered
Application Area:
Hard Surfaces, Commercial Laundry Applications, Bowls
Features:
Anti-Bacterial, Good Diluency, Hard Water Resistance, Effective Soil Removal, Cost Effective, Anti-Viral, Microbe Resistant
NUGEN® R-82G is Arxada’s first disinfectant cleaner with registrations under the US EPA and is being registered in selected countries under the Transitional Arrangements of the EU Biocidal Products Regulation; regulation (EU) 528/2012. NUGEN® R-82G offers you a solution to reduce complexity and increase your speed to market with a: Disinfectant based on a blend of quats Broad spectrum of efficacy, including activity against a range of viruses Low use dilution that contributes to sustainability goals Cross regional regulatory footprint Cost-effective sub-registration approaches Registered with US EPA and in selected European countries Simpler titration quality control methods for day to day batch release – a critical factor for the European market
NUGEN® Citric-Guard Wipes
Product Type:
Disinfectant Products, Sanitizers
Certifications & Compliance:
USDA BioPreferred, Design for Environment (DfE), EPA Registered
Features:
Microbe Resistant
NUGEN® Citric-Guard Wipes are a multifaceted solution that combine an effective, sustainable chemistry active, such as Citric Acid, with a compostable substrate based on viscose. They contain a solution based on a natural active ingredient that meets the principles of sustainability to drive positive change in our communities. NUGEN® Citric-Guard Wipes connect science with purpose for a better world. NUGEN® Citric-Guard Wipes are the complete sustainable solution for the Household and Professional markets.
Geogard® Boost PHC
INCI Name:
Propylene Glycol Caprylate, Phenoxyethanol
Functions:
Anti-Microbial Agent, Fungistatic Agent, Preservative, Bacteriostatic Agent
Benefit Claims:
Low Odor, Preservation, Antimicrobial, Easy-To-Dilute, Anti-Bacterial, Ease of Formulation, Compatibility, Anti-Fungal
Labeling Claims:
Ulta Beauty's Conscious Beauty, Organic, Halal, Environmentally Friendly, Sustainable, Non-GMO, Natural
Certifications & Compliance:
COSMOS, EU Compliant, IECIC (China), ISO 16128, Halal, EU Cosmetic Regulation 1223/2009 Compliant
Geogard® Boost PHC is an innovative one-step preservation solution, based on Phenoxyethanol. It delivers a broad spectrum of microbial protection with reduced levels of Phenoxyethanol in cosmetics applications like creams, lotions, moisturizers and conditioners.A single dose liquid solution which simplifies manufacturing logistics and helps meeting ever-changing market demand. Geogard® Boost PHC is easily formulated into conditioners and lotions, and is effective at a pH range of 5-8.INCI Name: Phenoxyethanol (CAS: 122-99-6), Propylene Glycol Caprylate (CAS: 68332-79-6 / 31565-12-5)Key Benefits of Geogard® Boost HPC:Optimized microbial performance at lower levels of PhenoxyethanolEnhanced efficacy spectrum and increased speed of kill compared to Phenoxyethanol alone Simplified manufacturing process (easily dilutable liquid concentrate)Applications Include: Bath & ShowerBody CareHair CareHair ConditioningSkin Care