Kolliphor

BASF Brand

Supplier:BASF

Products:9

Kolliphor® grades are used in oral, topical, and parenteral dosage forms, these excipients simplify the formulation process by exerting their versatile functionalities. The Kolliphor® family of solubilizers, emulsifiers, co-emulsifiers, and surfactants are ideal for addressing solubilization challenges to inhibit crystallization and enhance drug bioavailability.

View All Kolliphor Products

Kolliphor® CS 12

Chemical Name:Macrogol Cetostearyl Ether 12
Functions:Gelling Agent, Matrix Forming Agent, Surfactant, Solubilizer, Plasticizer, Emulsifier, Surfactant (Nonionic)
Dosage Form:Gels, Lotions, Creams
Labeling Claims:Sustainable
Certifications & Compliance:cGMP, EXCiPACT, European Pharmacopeia (Ph. Eur.), RSPO Certified Sustainable Palm Oil

Kolliphor® CS 12 is a white, wax-like mass with a mild odor, delivered in pellets. The product can be universally applied as a non-ionic emulsifier for pharmaceutical O/W emulsions.

Kolliphor® ELP

Chemical Name:PEG-35 Castor Oil
CAS Number:61791-12-6
Functions:Surfactant, Solubilizer, Gelling Agent, Matrix Forming Agent, Plasticizer, Emulsifier, Surfactant (Nonionic)
Dosage Form:Injectables, Soft Gels, Dispersions
Labeling Claims:Halal, Non-GMO, Melamine-free, Gluten-free, Aflatoxin-free, Microplastics-free, Dioxin-free, BSE-free, Phthalates-free, Latex-free, Additive-free, TSE-free, Allergen-free, Not Engineered With Nanomaterials, Contamination-free, Kosher
Certifications & Compliance:National Formulary (NF), United States Pharmacopeia (USP), FSSC 22000, ISO 14001, European Pharmacopeia (Ph. Eur.), Hazard Analysis Critical Control Point (HACCP), OHSAS, REACH Exempt (Europe), cGMP, DMF Type IV, ECOVADIS, International Standards For Phytosanitary Measures No. 15 (ISPM 15) Compliant

Kolliphor® ELP is a white to yellowish paste or cloudy liquid. It is a non-ionic solubilizer made by reacting castor oil with ethylene oxide in a molar ratio of 1:35. This is followed by a purification process. Kolliphor® ELP forms clear solutions in water and also dissolves in a wide range of organic solvents, such as ethanol, n-propanol, isopropanol, ethyl acetate, chloroform, carbon tetrachloride, trichloroethylene, toluene and xylene.

Kolliphor® P 188 Bio

Chemical Name:Poloxamer 188
CAS Number:9003-11-6
Functions:Solubilizer, Emulsifier, Lubricant, Surfactant
Labeling Claims:Sustainable
Certifications & Compliance:European Pharmacopeia (Ph. Eur.), China DMF, cGMP, US DMF, United States Pharmacopeia (USP)

Kolliphor® P 188 Bio is supplied as white to slightly yellowish, coarse grained powder with a waxy consistency. It is freely soluble in ethanol, freely soluble in water (opalescent solution), and is insoluble in diethyl ether, paraffin and fatty oils.

Kolliphor® PS 80

Chemical Name:Polysorbate 80
CAS Number:9005-65-6
Functions:Surfactant, Solubilizer, Gelling Agent, Matrix Forming Agent, Stabilizer, Plasticizer, Emulsifier, Surfactant (Nonionic), Co-Emulsifier, Skin Penetrant
Dosage Form:Soft Gels, Dispersions, Creams
Labeling Claims:Halal, Non-GMO, Melamine-free, Gluten-free, Aflatoxin-free, Dioxin-free, BSE-free, Sustainable, Phthalates-free, Latex-free, TSE-free, Allergen-free, Not Engineered With Nanomaterials, Contamination-free, Kosher
Certifications & Compliance:National Formulary (NF), United States Pharmacopeia (USP), ISO 14001, European Pharmacopeia (Ph. Eur.), RSPO Certified Sustainable Palm Oil, OHSAS, Japan Pharmacopeia (JP), REACH Exempt (Europe), cGMP, EXCiPACT, ECOVADIS, International Standards For Phytosanitary Measures No. 15 (ISPM 15) Compliant

Kolliphor® PS 80 is an amber liquid with a faint characteristic odor. Kolliphor® PS 80 is used as a non-ionic surfactant and oil-in-water emulsifier, as plasticizer in a range of solid dispersions and oral dosage forms. It is a non-ionic, hydrophilic emulsifier with broad pH range applicability and good skin tolerance in topical formulations.

Kolliphor® SLS Fine

Chemical Name:Sodium Lauryl Sulfate
CAS Number:151-21-3
Functions:Surfactant, Solubilizer, Wetting Agent, Dispersant, Surfactant (Anionic), Gelling Agent, Matrix Forming Agent, Plasticizer, Emulsifier, Lubricant
Dosage Form:Foams, Emulsions, Creams
Labeling Claims:Halal, Non-GMO, Melamine-free, Gluten-free, Aflatoxin-free, Nitrosamines-free, Dioxin-free, BSE-free, Sustainable, Phthalates-free, Latex-free, Additive-free, TSE-free, Allergen-free, Not Engineered With Nanomaterials, Contamination-free, Kosher
Certifications & Compliance:National Formulary (NF), United States Pharmacopeia (USP), ISO 14001, European Pharmacopeia (Ph. Eur.), RSPO Certified Sustainable Palm Oil, OHSAS, Japan Pharmacopeia (JP), REACH Exempt (Europe), ISO 9001, cGMP, EXCiPACT, China DMF, ECOVADIS, Generally Recognized As Safe (GRAS), International Standards For Phytosanitary Measures No. 15 (ISPM 15) Compliant
Synonyms:Akyposal SDS, NaDS, Natrium Laurylsulfuricum, SDS, SLS, Sodium Dodecanesulfate, Sodium Dodecyl Sulfate, Sodium Laurilsulfate, Sulfuric Acid Monododecyl Ester Sodium Salt

Kolliphor® SLS Fine is a white to off-white powder with faint characteristic odor. The product tends to agglomerate. The agglomerates exhibit a yellowish to brownish color and are completely soluble by heating and stirring. Solubilizing, the agglomerates does not influence the product quality. The product is characterized by a very high active substance matter and a very low content of inorganic salts and unsulfated fatty alcohol. Preferred areas of application are pharmaceutical emulsion, tablets and cream shampoos.

Kolliphor® HS15

Chemical Name:Polyethylene glycol-15-hydroxystearate
CAS Number:70142-34-6
Functions:Surfactant, Solubilizer, Dispersant, Stabilizer, Emulsifier, Surfactant (Nonionic)
Dosage Form:Transdermal Patches, Injectables, Emulsions, Soft Gels, Creams
Labeling Claims:Halal, Melamine-free, Gluten-free, Aflatoxin-free, Plant-Based, Nitrosamines-free, Microplastics-free, Dioxin-free, BSE-free, Sustainable, Phthalates-free, Latex-free, Natural, Additive-free, TSE-free, Allergen-free, Not Engineered With Nanomaterials, Contamination-free, Kosher, Naturally Derived
Certifications & Compliance:DMF Type V, National Formulary (NF), United States Pharmacopeia (USP), FSSC 22000, ISO 14001, European Pharmacopeia (Ph. Eur.), Certificates of Suitability (CEP), US DMF, FDA Compliant, OHSAS, REACH Exempt (Europe), cGMP, DMF Type IV, ECOVADIS, International Standards For Phytosanitary Measures No. 15 (ISPM 15) Compliant

Kolliphor® HS15 is a yellowish white paste at room temperature that becomes a liquid at approximately 30°C. It dissolves in water, ethanol and 2-propanol to form clear solutions. Its solubility in water decreases with increasing temperatures. It is insoluble in liquid paraffin.

Kolliphor® P 188 Micro Geismar

Chemical Name:Poloxamer 188
CAS Number:9003-11-6
Functions:Solubilizer, Wetting Agent, Dispersant, Gelling Agent, Plasticizer, Emulsifier, Lubricant
Dosage Form:Gels, Transdermal Patches, Injectables, Foams, Emulsions, Soft Gels, Dispersions, Creams
Labeling Claims:Halal, Non-GMO, Melamine-free, Gluten-free, Aflatoxin-free, Dioxin-free, BSE-free, Sustainable, Phthalates-free, Latex-free, TSE-free, Allergen-free, Not Engineered With Nanomaterials, Contamination-free, Kosher
Certifications & Compliance:United States Pharmacopeia (USP), European Pharmacopeia (Ph. Eur.), FDA Compliant, OHSAS, REACH Exempt (Europe), ISO 9001, cGMP, DMF Type IV, ECOVADIS, International Standards For Phytosanitary Measures No. 15 (ISPM 15) Compliant

Kolliphor® P 188 Micro Geismar is supplied as white to slightly yellowish microbeads. It is readily soluble in water and ethanol and other mainly polar solvents. It is insoluble in ether, paraffin and fatty oils.

Kolliphor® P 407 Micro Geismar

Chemical Name:Poloxamer 407
CAS Number:9003-11-6
Functions:Solubilizer, Wetting Agent, Dispersant, Gelling Agent, Plasticizer, Emulsifier, Lubricant
Dosage Form:Foams, Emulsions, Soft Gels, Dispersions, Creams, Gels
Labeling Claims:Non-GMO, Melamine-free, Gluten-free, Aflatoxin-free, Microplastics-free, Dioxin-free, BSE-free, Phthalates-free, Latex-free, TSE-free, Allergen-free, Not Engineered With Nanomaterials, Contamination-free
Certifications & Compliance:United States Pharmacopeia (USP), European Pharmacopeia (Ph. Eur.), FDA Compliant, OHSAS, REACH Exempt (Europe), ISO 9001, cGMP, DMF Type IV, ECOVADIS, International Standards For Phytosanitary Measures No. 15 (ISPM 15) Compliant

Kolliphor® P 407 Micro Geismar is supplied as white to slightly yellowish microbeads. It is readily soluble in water and ethanol and other mainly polar solvents. It is insoluble in ether, paraffin and fatty oils. It offers effective content uniformity, solubilization and increase oral bioavailability of bioactive

Kolliphor® SML 20

Chemical Name:Sorbitan Monolaurate
Functions:Plasticizer, Surfactant, Solubilizer, Emulsifier, Surfactant (Nonionic)
CAS Number:1338-39-2
Dosage Form:Gels, Foams, Suspension, Lotions, Tablets, Aerosols, Capsules, Creams
Labeling Claims:Halal, Kosher
Certifications & Compliance:Halal, European Pharmacopeia (Ph. Eur.), RSPO Certified Sustainable Palm Oil, GMP, Kosher
Synonyms:E 493, Lauric acid sorbitan ester, Sorbitan lauric acid monoester, Sorbitan monododecanoate, Sorbitan monolauric acid ester, Tween 28

Kolliphor® SML 20 is a versatile ingredient perfect for various applications. In skincare, it is employed to create a lightweight, fast-spreading cream for achieving even skin coverage. Additionally, Kolliphor® SML 20 serves as a non-ionic surfactant and emulsifier. It can also function as a plasticizer for tablet coatings in pharmaceutical formulations.

Knowde Brand Summary

Identification

Chemical Family: Polysorbates,
Sorbitan Esters
Chemical Name: Macrogol Cetostearyl Ether 12,
PEG-35 Castor Oil,
Poloxamer 188,
Poloxamer 407,
Polyethylene glycol-15-hydroxystearate,
Polysorbate 80,
Sodium Lauryl Sulfate,
Sorbitan Monolaurate
Country of Origin: Germany,
United States of America (USA)
Ingredient Origin: Natural Origin,
Non-Animal Origin,
Plant Origin,
Synthetic,
Vegetable Origin
Technologies: Pharmaceuticals & Nutraceuticals
Product Families: Excipients
Base Fluids, Glidants & Lubricants,
Emulsifiers & Stabilizers,
Formulation & Processing Aids,
Other Excipients,
Solvents & Solubilizers
Pharma & Nutraceuticals Functions: Co-Emulsifier,
Dispersant,
Emulsifier,
Gelling Agent,
Lubricant,
Matrix Forming Agent,
Plasticizer,
Skin Penetrant,
Solubilizer,
Stabilizer,
Surfactant,
Surfactant (Anionic),
Surfactant (Nonionic),
Wetting Agent

Applications & Uses

Markets: Healthcare & Pharma
Applications: Drug Delivery & Care Solutions
Ophthalmic,
Oral,
Parenteral,
Topical,
Transdermal
Dosage Form: Aerosols,
Capsules,
Creams,
Dispersions,
Emulsions,
Foams,
Gels,
Injectables,
Lotions,
Soft Gels,
Suspension,
Tablets,
Transdermal Patches
Manufacturing Technology: Capsule Filling,
Direct Compression,
Dry Granulation,
Hot Melt Extrusion,
Melt Granulation,
Spray Drying,
Wet Granulation

Knowde Brand Highlights

Benefits: Diverse range of non-ionic and anionic surfactants and emulsifiers

Highly purified, low toxicity solubilizers available for parenteral and oral applications

Consists of polymers suitable for both instant and modified release applications

Select products meet quality, consistency, and performance to address upstream and downstream biologic manufacturing

Composed of select RSPO (Roundtable on Sustainable Palm Oil) products