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Flavonoid Micronized Diosmin

Bordas Micronized Diosmin, is a flavonoid harnessed as a venotonic for the enduring management of Chronic Venous Diseases (CVD), varicose veins, hemorrhoids, spider veins, and the discomfort associated with heavy leg syndrome.This GMP-certified Active Pharmaceutical Ingredient (API) is the number one in its class for the management of these pathologies. Micronisation improves bioavailability among other properties of the active ingredient

Brand: Flavonoid (21 products)

Chemical Name: Diosmin

CAS Number: 520-27-4

Active Component: Diosmin

Synonyms: 3',5,7-trihydroxy-4'-methoxyflavone-7-rutinoside, Diosmetin 7-Neohesperidoside, Diosmetin 7-O-Rutinoside, Diosmine, Neodiosmin

Enhanced TDS

Knowde-enriched technical product data sheet

Identification & Functionality

Active Component
Diosmin
Chemical Name
Diosmin
Molecular formula
C₂₈H₃₂O₁₅
Technologies
Pharmaceuticals & Nutraceuticals
Product Families
Pharmaceuticals & Nutraceuticals — Nutraceuticals & Supplements
Phytochemicals & Plant Extracts,
Supplements & Functional Ingredients
Pharmaceuticals & Nutraceuticals — Pharmaceutical Actives & Precursors
Active Pharmaceutical Ingredients (APIs)

Features & Benefits

Benefit Claims (Health)
Venotonic
Labeling Claims
Aflatoxin-free,
Allergen-free,
Animal Products-free,
BSE-free,
Gluten-free,
Halal,
Irradiation-free,
Kosher,
Lacto-Ovo-Vegetarian,
Latex-free,
Melamine-free,
Non-GMO,
Pareve,
TSE-free,
Vegan,
Vegetarian

Properties

Physical Form
Powder
Appearance
Greyish-yellow or light yellow hygroscopic powder
Odor
Odorless
Soluble in
Dimethyl Sulphoxide, Dilute Solutions of Alkali Hydroxides
Insoluble in
Water, ethanol (96%)
Typical Properties
ValueUnitsTest Method / Conditions
Molecular Weight 608.5--
Water Contentmax 6.0%-
Sulphated Ashmax. 0.2%-
Bulk Densitymax. 0.5g/ml-
Decomposition Point272 - 283ºC-
Pyridine Contentmax. 200ppm-
Acetic Acid Contentmax. 5000ppm-
Iodine Contentmax. 0.1%-
Particle Size (< 5μm)90.0%-
Purity (Diosmin)min. 90.0 - 102.0%HPLC
Purity (Hesperidin )max. 4.0%HPLC
Purity (Isorhoifolin)max. 3.0%HPLC
Purity (Acetoisovanillone)max. 0.5%HPLC
Total Impuritiesmax. 8.5%HPLC
Purity (Linarine)max. 3.0%HPLC
Purity (6-Iododiosmine)max. 0.6%HPLC
Purity (Diosmetin)max. 2.0%HPLC
Any Other Impuritymax. 0.4%HPLC
Particle size (< 2μm )50.0%-
Microbiological Values
ValueUnitsTest Method / Conditions
Escherichia coliAbsent/g-
Total Aerobic Microbial Countmax. 10³CFU/g-
Total Yeast and Mold Countmax. 10² CFU/g-
Heavy Metals
ValueUnitsTest Method / Conditions
Heavy Metalsmax. 20ppm-

Regulatory & Compliance

Certifications & Compliance
Certificates of Suitability (CEP),
European Pharmacopeia (Ph. Eur.),
GMP,
ICH Normatives,
ISO 14000,
ISO 45001,
ISO 9001,
Manufacturing License by MOH

Packaging & Availability

Packaging Type
Bags,
Drums
Packaging Information

Hermetically sealed, lined drums of 50 and 25 Kg or big-bags of 350 Kg net weight

Storage & Handling

Shelf Life
5 years
Storage and Shelf Life Conditions
  • In full and well closed container. Keep at room temperature in a dark and dry place. 
  • Shelf Life : 5 years