Knowde Enhanced TDS
Identification & Functionality
- Carrier
- Ingredient Origin
- Cosmetic Ingredients Functions
- Technologies
Features & Benefits
- Benefit Claims
Applications & Uses
- Markets
- Applications
- Baby Care Applications
- Color Cosmetic Applications
- Hair Care Applications
- Skin Care Applications
- Sun Care Applications
- Use Level
- 1-5% (Skin care preparations)
- Application pH Range
- 3-10%
- Mode Of Action
Maintaining a sufficient level of hydration is one of the fundamental properties of the skin. Water in the stratum corneum (SC) is mainly present in the corneocytes and minimally in the intercellular regions. In the upper layers of the SC the average water level in corneocytes is about 15 to 30 percent. The barrier function of the SC is correlated to the actual amount of water inside the corneocytes. When the water content of the corneocytes in the upper layers of the SC drops below 10 percent, the corneocytes become too small to completely fill the space between the extra cellular lipid matrix, accounting for loss of barrier function. The level of SC hydration is the product of an equilibrium of environmental humidity and the SC’s hygroscopic properties.
A change in environmental humidity e.g. moving from a humid environment into a dry environment, such as an air-conditioned room or going on a ski holiday (winter xerosis), can have major consequences. The SC loses water and its barrier function is impaired. This can result in dry skin and itchiness (pruritus). In order to maintain a sufficient level of hydration the SC contains hygroscopic molecules - the Natural Moisturizing Factors (NMF). Although the NMF are very potent in their ability to retain water in the SC they are constantly depleted through normal every day activities such as skin cleansing. Maintaining a sufficient level of hydration in the face of daily showering, airconditioned rooms, and airplanes is not easy and poses the cosmetic chemist to a great challenge.
DayMoist CLR, a multi-potent natural based moisturizer, helps to easily develop moisturizing formulations required by modern consumers. It contains hygroscopic molecules originating from the root of Beta vulgaris and hydrolysed starch. When applied onto the skin these molecules immediately raise the hydration level in the SC, making the skin smoother and more supple, and ensuring a healthy appearance.
In order to determine in vivo the level of hydration CLR combined corneometry, to estimate the amount of water in the SC, with Confocal Raman Microspectroscopy, a non-invasive method for determining molecular concentration profiles in the SC. During the first 24 hours after a single application of a formulation containing DayMoist CLR, the elevated concentration of NMF showed a good correlation with the results obtained using corneometry. This allows the conclusion that the new active helps in significantly elevating the NMF concentration after a single application, leading to a higher level of hydration.
The fast-acting significant NMF-elevating and moisturizing effect lasts for at least 24 hours when added to a leave-on formulation at 3 percent. Just 1 percent leads to a significant moisturisation for over 8 hours, making the active particularly suitable for mass-market formulations. In addition,DayMoist CLR is a natural, colorless and easy to formulate product, fitting all well-known market trends.
- Recommended Uses
- DayMoist CLR is intended for application for every day care cosmetics and cosmetics for dry skin.
- DayMoist CLR has shown to elevate the concentration of NMF after a single application, resulting in a higher level of hydration for, depending on the dosage used, more than 24 hours.
- It can be used in emulsified, aqueous and aqueous-alcoholic skin moisturizing cosmetics.
- Processing
DayMoist CLR is relatively thermostable and may be heated briefly to the temperatures required for the manufacture of emulsified preparations. In the manufacture of emulsified preparations DayMoist CLR is dissolved in the water phase.
In the manufacture of aqueous-alcoholic preparations DayMoist CLR is added to the alcoholwater mixture.
DayMoist CLR does not affect the color of cosmetics. The weak odor of DayMoist CLR can be masked in cosmetics by perfume oils.
Properties
- Physical Form
- Odor
- Weak Specific
- Appearance
- Aqueous solution
Regulatory & Compliance
- Certifications & Compliance
Safety & Health
- Physiological Safety
Acute oral toxicity
DayMoist CLR is based on ingredients, which have a long tradition in food. DayMoist CLR is considered to be non-toxic and safe in cosmetic use at the levels advised by us.
Eye irritation potential
DayMoist CLR was tested at a concentration of 10 % on the chorioallantoic membrane of the hen's egg where it produced an irritation index of 0.00 and was classified as "non-irritant".
Skin compatibility
Human Repeated Insult Patch Test:
An aqueous solution of 30% DayMoist CLR, with pH 5.3, was applied on the back of 103 volunteers according to a regimen, comprising 9 sequential 24-hour applications and 2 concurrently conducted 24-hour challenge applications, using partially occlusive patching devices. This solution was found to be neither a clinically significant skin irritant nor a skin sensitizer.In another study, undiluted DayMoist CLR was applied on 50 volunteers (among these 22 individuals with normal skin, 6 sufferers from eczema, 2 allergic and 20 individuals with sensitive skin) for 48 hours in a patch test. This test as well, showed no skin irritant effects. DayMoist CLR can therefore be classified as harmless as regards to the possibility of skin irritation and skin sensitization.
Mutagenicity
According to a reverse mutation assay using bacteria DayMoist CLR showed neither on 4 strains of Salmonella typhimurium nor on E. coli WP2 uvrA any mutagenic action.
Packaging & Availability
- Packaging Information
- Available pack sizes: 1 kg, 5 kg, 25 kg
- Sample size: 50 g
Storage & Handling
- Storage and Handling
At room temperature (15-25°C), in well-closed containers, protected from light. DayMoist CLR should not be stored for longer than 2 years before processing.
If exposed to cold temperatures slight crystallization may occur; this process can be reversed by slight heating to 40°C and does not influence the quality of the product.