Knowde Enhanced TDS
Identification & Functionality
- Carrier
- Ingredient Origin
- Cosmetic Ingredients Functions
- Technologies
Features & Benefits
- Benefit Claims
- Labeling Claims
Applications & Uses
- Markets
- Color Cosmetic Applications
- Skin Care Applications
- Use Level
- 2 – 5 %
- Application pH Range
- 5.8 – 7.0
- Mode of Action
The skin beneficial effect of ProBioBalance CLR NP relies on the synergy produced by Bifidobacteria which have been disintegrated in a milk fraction. By nutrilizing skin cells their vitality is increased, thus enabling them to counteract environmental stress more efficiently. Skin cells pretreated with the probioactive resist UV stress by rebalancing the immune system (anti-immunosuppressive effect) or by preventing proteolytic degradation of the extracellular matrix(ECM). Vitalisation of tired, stressed skin could be proven on humans.
- Recommended Uses
ProBioBalance CLR NP is designed to rebalance tired, stressed skin. It can be used in emulsified and gel type skin care products.
- Processing
Short-term heating to approx. 40 °C does not affect bioactivity. The pH of formulations containing ProBioBalance CLR NP should be in the range of 5.8 – 7.0. Avoid alkaline pH values. Shake or agitate before use to homogenize.
Properties
- Physical Form
- Odor
- Characteristic
- Appearance
- Opaque liquid
- Soluble in
- Water
Safety & Health
- Physiological Safety
Acute oral toxicity
Oral toxicity testing on rats was not conducted with this product because the used milk fraction and lysates of Bifidobacteria were tested separately before and are known to be non-toxic.
Skin compatibility: Human patch test
Undiluted ProBioBalance CLR NP was applied on 50 volunteers (among these 23 individuals with normal skin, 9 sufferers from eczema, 2 allergic and 16 individuals with sensitive skin) for 48 hours in a patch test. This test showed neither skin irritant nor sensitizing effects. Thus ProBioBalance CLR NP can be classified as harmless as regards the possibility of skin irritation.
Eye irritation potential
The results were obtained with the product “ProBioBalance CLR” which differs from "ProBioBalance CLR NP " only by the preservative system used (ProBioBalance CLR: Phenoxyethanol, Methylparaben, Dehydroacetic acid; ProBioBalance CLR NP: Phenylethanol) ProBioBalance CLR was tested undiluted on the chorioallantoic membrane of the hen's egg. With an irritation index of 0.00 it was classified as "non irritant".
Packaging & Availability
- Packaging
Available pack sizes: 1 kg; 5 kg; 25 kg
Sample size: 50 g
Storage & Handling
- Storage And Handling
If kept at a temperature between 15 °C and 25 °C in well-closed containers, ProBioBalance CLR NP is stable for at least 1 year. Once opened, product packs should be fully used.
- Preservative System
Stabilized with phenethyl alcohol