Knowde Enhanced TDS
Identification & Functionality
- Chemical Family
- INCI Name
- Ingredient Origin
- Cosmetic Ingredients Functions
- CAS No.
- 106-14-9
- EC No.
- 203-366-1
- Technologies
Features & Benefits
- Benefit Claims
- Labeling Claims
- Product Highlights
- High purity, sustainable Hydroxystearic acid
- Manufactured using green technology
- Activates the master cell regulator PPARα in vitro
- Strong Collagen I and III stimulation ex vivo
- Prevents UV-induced expression of MMP-1 ex vivo
- Reduces formation of UV-induced sunburn cells ex vivo
- Reduces UV stress marker p53 ex vivo
- Key Attributes
- Visibly reduces the appearance of conspicuous facial pores
- Visibly reduces the appearance of age spot
- Makes skin look younger and improves appearance after the age of 30
Applications & Uses
- Markets
- Applications
- Bath & Shower Applications
- Color Cosmetic Applications
- Hair Care Applications
- Personal Hygiene Applications
- Skin Care Applications
- Sun Care Applications
- Use Level
- 0.01
- Mode Of Action
DSM researchers discovered that, in vitro, BEAUACTIVE® activates the master cell regulator PPARα which triggers multi-target effects for better skin. Upon UVB stress BEAUACTIVE® hinders the production of both sunburn cells and the stress marker p53 which can increase skin pigmentation. BEAUACTIVE® also helps the skin to make more collagen, a key structural factor in the prevention of conspicuous facial pores.
- Multi-Target Mode of Action
- In the in silico model, BEAUACTIVE® docks into PPARα, a master cell regulator whose activation influences multiple targets.
- BEAUACTIVE® improves cell protection by reducing the production of UV-induced sunburn cells.
- BEAUACTIVE® decreases UV stress marker p53 leading to reduced production of melanin. It is therefore effective at correcting age spots.
- BEAUACTIVE® decreases UV-induced MMP expression and increases Collagen I and III to help in the reduction of conspicuous facial pores.
Properties
- Insoluble in
- Water
- Soluble in
- Cosmetic Emollients
Regulatory & Compliance
- Certifications & Compliance
- Chemical Inventories
Technical Details & Test Data
- Test Data
In vivo
Eight-week placebo-controlled, double blind study
- 37 volunteers (aged 38–65, mean 53.4 yrs) received product with 1% BEAUACTIVE®
- 38 volunteers (aged 34–65, mean 54.4 yrs) received the placebo formulation
- Volunteers had to apply their respective test formulation to the wholeface twice daily (mornings and evenings) for 8 weeks
- The assessment methods used were: 1. High resolution photo (VISIA CR) and 2. Image analysis (pores and age spots)
Reduction of segmented pore surfaces (blue)
Reduction of selected age spot (cross-polarized images)
Selected age spot of Subject #20 treated with 1% BEAUACTIVE®
Storage & Handling
- Shelf Life
- 36 Months