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BEL-EVEN®
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Producer: 
DSM
Brand: 
BEL-EVEN
Future-Proof Your Skin from the Effects of Daily Stress. BEL-EVEN® is a patented synthetic small molecule that helps counteract the damaging effects of stress on the skin. In vitro, BEL-EVEN® reversibly and selectively inhibits the key enzyme 11β-HSD1, which generates cortisol in the skin. BEL-EVEN® visibly reduces the signs of a stressful lifestyle, and improves skin elasticity and density as well as barrier functionality. For detailed regulatory or quality information, please contact the supplier.

BEL-EVEN®

Producer: 
DSM
Brand: 
BEL-EVEN
Future-Proof Your Skin from the Effects of Daily Stress. BEL-EVEN® is a patented synthetic small molecule that helps counteract the damaging effects of stress on the skin. In vitro, BEL-EVEN® reversibly and selectively inhibits the key enzyme 11β-HSD1, which generates cortisol in the skin. BEL-EVEN® visibly reduces the signs of a stressful lifestyle, and improves skin elasticity and density as well as barrier functionality. For detailed regulatory or quality information, please contact the supplier.
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Features & Benefits

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Origin
Synthetic
Product Highlights
  • Does not contain intentionally added substances regulated/listed as preservative
  • Patented new to the world molecule with well-defined innovative mode of action
  • Rebalances cortisol level in skin by inhibiting the enzyme 11β-HSD1
  • Sustainable production process
Key Attributes
  • Fights against stress-induced collagen loss and skin thinning
  • Leads to more supple-looking skin with improved skin elasticity
  • Significantly improves skin density and greater barrier integrity

Technical Details & Test Data

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Mode Of Action
  • The human skin naturally responds to periods of stress with the formation of more cortisol through a particular enzyme; 11β-HSD1. This release of cortisol, the so-called stress hormone, is a normal and healthy adaptation reflex. However, cortisol can turn into an enemy of the skin if it remains in excess over a long period of time.
  • BEL-EVEN® selectively inhibits the enzyme 11β-HSD1, particularly in keratinocytes, but also in fibroblasts, leading to rebalanced cortisol levels. This well-defined mechanism helps your skin to manage the undesired effects of a stressful lifestyle and skin elasticity, density and barrier functionality will improve.

Storage & Handling

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Shelf Life
24 months

Documents (3)

Name
Type
DSM Personal Care Brochure
Other
BEL-EVEN® Safety Data Sheet
Safety Data Sheet
Skin Bioactives Brochure
Other