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BEL-EVEN®
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BEL-EVEN®

Future-Proof Your Skin from the Effects of Daily Stress. BEL-EVEN® is a patented synthetic small molecule that helps counteract the damaging effects of stress on the skin. In vitro, BEL-EVEN® reversibly and selectively inhibits the key enzyme 11β-HSD1, which generates cortisol in the skin. BEL-EVEN® visibly reduces the signs of a stressful lifestyle, and improves skin elasticity and density as well as barrier functionality. For detailed regulatory or quality information, please contact the supplier.
Product Resources

Knowde Enhanced TDS

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Identification & Functionality

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Features & Benefits

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Origin
Synthetic
Product Highlights
  • Does not contain intentionally added substances regulated/listed as preservative
  • Patented new to the world molecule with well-defined innovative mode of action
  • Rebalances cortisol level in skin by inhibiting the enzyme 11β-HSD1
  • Sustainable production process
Key Attributes
  • Fights against stress-induced collagen loss and skin thinning
  • Leads to more supple-looking skin with improved skin elasticity
  • Significantly improves skin density and greater barrier integrity

Applications & Uses

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Properties

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Ingredient Origin
Physical Form
Physical Form
Liquid
Color
Colorless
Miscible In
Water

Regulatory & Compliance

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Technical Details & Test Data

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Mode Of Action
  • The human skin naturally responds to periods of stress with the formation of more cortisol through a particular enzyme; 11β-HSD1. This release of cortisol, the so-called stress hormone, is a normal and healthy adaptation reflex. However, cortisol can turn into an enemy of the skin if it remains in excess over a long period of time.
  • BEL-EVEN® selectively inhibits the enzyme 11β-HSD1, particularly in keratinocytes, but also in fibroblasts, leading to rebalanced cortisol levels. This well-defined mechanism helps your skin to manage the undesired effects of a stressful lifestyle and skin elasticity, density and barrier functionality will improve.

Storage & Handling

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Shelf Life
24 months

Documents (3)

Document Name
Type
Products
Safety Data Sheet
BEL-EVEN®
Safety Data Sheet
Products: BEL-EVEN®
Other
PENTACARE-HP PF, ALPAFLOR® SAMBUCUS AO, ALPAFLOR® SCUTELLARIA AO, PREREGEN® PF, STAY-C® 50, TILAMAR® OP 40, TILAMAR® Fix A1000, TILAMAR® Quat 2240, TILAMAR® Quat 640, TILAMAR® Boost 150, VALVANCE® Touch 210, SYN® GLOW, SYN® STAR, SYN® TACKS, DSM Ascorbic Acid Fine Granular, COLHIBIN PF, STIMU-TEX® AS, ALL-Q (Coenzyme Q10) plus, PEPHA®-TIGHT, PENTAVITIN®, PEPHA®-CTIVE, ALPAFLOR® ARTEMISIA AO, ALPAFLOR® BUDDLEJA AO, DSM DL-α-Tocopheryl Acetate, PEPHA®-AGE, ALPAFLOR® NECTAPURE PF, ALPAFLOR® IMPERATORIA AO, DSM D-Biotin, ALPAFLOR® ALP-SEBUM CB, ALPAFLOR® EDELWEISS B, ALPAFLOR® EDELWEISS EP, ALPAFLOR® GIGAWHITE, ALPAFLOR® LINUM AO, BeauPlex® VH, ALPAFLOR® MARRUBIUM AO, DSM ALPHA-ARBUTIN, DISMUTIN® PF, DSM ARGAN OIL, DSM Ethyl Panthenol, DSM DL-α-Tocopherol, DSM D-Panthenol, DSM ERYTHRULOSE, DSM Folic acid, DSM HYALURONIC ACID-BT, HYDROLASTAN PF, HYASOL PF, DSM Mixed Tocopherols 95, IRICALMIN PF, DSM PHYTANTRIOL, DSM Niacinamide PC, LACTOMIDE, DSM Pyridoxine Hydrochloride, DSM RETINOL GS 50, DSM SERICIN, DSM Vitamin A Palmitate 1.7 MIU/g, ELHIBIN® PF, PEPHA®-PROTECT, MELAWHITE® PF, MELFADE® PF, PARSOL® 5000, PARSOL® Guard, PARSOL® HMS, PARSOL® HS, PARSOL® SLX, PENTAGLYCAN PF, PHYTALURONATE® PF, REGU®-FADE, REGU®-SEB, REGU®-SCENCE, REVITALIN® PF, REGU®-SLIM, REGU®-STRETCH, SETAKOL® PF, SYN® AKE, SYN® EYE, SYN® TC, SYN® HYCAN, PARSOL® Max, SYN® UP, REGU®-AGE PF, DSM Ascorbic Acid Fine Powder, BEAUACTIVE®, Life’s GLA™ ‘10’ n-6 Oil, BEL-EVEN®, DSM D-Panthenol 75L, OXY 229 PF, PENTACARE-NA PF, Life’s GLA™ '25' n-6 Oil, DSM DL-Panthenol 50 L, CEPHALIPIN NP 2, DSM Ascorbic Acid Ultra Fine Powder, DSM D-α-Tocopheryl Acetate, DSM Vitamin A Palmitate 1.0 MIU/g (tocopherol), DSM Vitamin A Palmitate 1.0 MIU/g (BHA/BHT), DSM Vitamin A Palmitate 1.7 MIU/g (tocopherol), DSM Vitamin A Palmitate 1.7 MIU/g (BHA/BHT), DSM Vitamin A Palmitate/M 1.0 MIU/g (tocopherol), PARSOL® 1789, PARSOL® 340, PARSOL® EHS, PARSOL® Shield, PARSOL® MCX, PARSOL® TX, PARSOL® ZX, DSM ALLANTOIN, SYN® COLL, ALPAFLOR® MALVA AO, AMPHISOL® A, AMPHISOL® K, LIPOGARD, DSM COLLAGEN 1%, DSM COLLAGEN BOVINE 1%, VALVANCE® Look 100, VALVANCE® Touch 250, DSM Vitamin A Acetate 1.5 MIU/g
Other
Products: PENTACARE-HP PF, ALPAFLOR® SAMBUCUS AO, ALPAFLOR® SCUTELLARIA AO, PREREGEN® PF, STAY-C® 50, TILAMAR® OP 40, TILAMAR® Fix A1000, TILAMAR® Quat 2240, TILAMAR® Quat 640, TILAMAR® Boost 150, VALVANCE® Touch 210, SYN® GLOW, SYN® STAR, SYN® TACKS, DSM Ascorbic Acid Fine Granular, COLHIBIN PF, STIMU-TEX® AS, ALL-Q (Coenzyme Q10) plus, PEPHA®-TIGHT, PENTAVITIN®, PEPHA®-CTIVE, ALPAFLOR® ARTEMISIA AO, ALPAFLOR® BUDDLEJA AO, DSM DL-α-Tocopheryl Acetate, PEPHA®-AGE, ALPAFLOR® NECTAPURE PF, ALPAFLOR® IMPERATORIA AO, DSM D-Biotin, ALPAFLOR® ALP-SEBUM CB, ALPAFLOR® EDELWEISS B, ALPAFLOR® EDELWEISS EP, ALPAFLOR® GIGAWHITE, ALPAFLOR® LINUM AO, BeauPlex® VH, ALPAFLOR® MARRUBIUM AO, DSM ALPHA-ARBUTIN, DISMUTIN® PF, DSM ARGAN OIL, DSM Ethyl Panthenol, DSM DL-α-Tocopherol, DSM D-Panthenol, DSM ERYTHRULOSE, DSM Folic acid, DSM HYALURONIC ACID-BT, HYDROLASTAN PF, HYASOL PF, DSM Mixed Tocopherols 95, IRICALMIN PF, DSM PHYTANTRIOL, DSM Niacinamide PC, LACTOMIDE, DSM Pyridoxine Hydrochloride, DSM RETINOL GS 50, DSM SERICIN, DSM Vitamin A Palmitate 1.7 MIU/g, ELHIBIN® PF, PEPHA®-PROTECT, MELAWHITE® PF, MELFADE® PF, PARSOL® 5000, PARSOL® Guard, PARSOL® HMS, PARSOL® HS, PARSOL® SLX, PENTAGLYCAN PF, PHYTALURONATE® PF, REGU®-FADE, REGU®-SEB, REGU®-SCENCE, REVITALIN® PF, REGU®-SLIM, REGU®-STRETCH, SETAKOL® PF, SYN® AKE, SYN® EYE, SYN® TC, SYN® HYCAN, PARSOL® Max, SYN® UP, REGU®-AGE PF, DSM Ascorbic Acid Fine Powder, BEAUACTIVE®, Life’s GLA™ ‘10’ n-6 Oil, BEL-EVEN®, DSM D-Panthenol 75L, OXY 229 PF, PENTACARE-NA PF, Life’s GLA™ '25' n-6 Oil, DSM DL-Panthenol 50 L, CEPHALIPIN NP 2, DSM Ascorbic Acid Ultra Fine Powder, DSM D-α-Tocopheryl Acetate, DSM Vitamin A Palmitate 1.0 MIU/g (tocopherol), DSM Vitamin A Palmitate 1.0 MIU/g (BHA/BHT), DSM Vitamin A Palmitate 1.7 MIU/g (tocopherol), DSM Vitamin A Palmitate 1.7 MIU/g (BHA/BHT), DSM Vitamin A Palmitate/M 1.0 MIU/g (tocopherol), PARSOL® 1789, PARSOL® 340, PARSOL® EHS, PARSOL® Shield, PARSOL® MCX, PARSOL® TX, PARSOL® ZX, DSM ALLANTOIN, SYN® COLL, ALPAFLOR® MALVA AO, AMPHISOL® A, AMPHISOL® K, LIPOGARD, DSM COLLAGEN 1%, DSM COLLAGEN BOVINE 1%, VALVANCE® Look 100, VALVANCE® Touch 250, DSM Vitamin A Acetate 1.5 MIU/g
Other
PENTACARE-HP PF, PREREGEN® PF, COLHIBIN PF, STIMU-TEX® AS, ALL-Q (Coenzyme Q10) plus, PEPHA®-TIGHT, PENTAVITIN®, PEPHA®-CTIVE, PEPHA®-AGE, DSM ALPHA-ARBUTIN, DISMUTIN® PF, DSM ARGAN OIL, DSM ERYTHRULOSE, DSM HYALURONIC ACID-BT, HYDROLASTAN PF, HYASOL PF, IRICALMIN PF, DSM PHYTANTRIOL, LACTOMIDE, DSM SERICIN, ELHIBIN® PF, PEPHA®-PROTECT, MELAWHITE® PF, MELFADE® PF, PENTAGLYCAN PF, PHYTALURONATE® PF, REGU®-FADE, REGU®-SEB, REGU®-SCENCE, REVITALIN® PF, REGU®-SLIM, REGU®-STRETCH, SETAKOL® PF, REGU®-AGE PF, BEAUACTIVE®, Life’s GLA™ ‘10’ n-6 Oil, BEL-EVEN®, OXY 229 PF, PENTACARE-NA PF, Life’s GLA™ '25' n-6 Oil, CEPHALIPIN NP 2, DSM ALLANTOIN, LIPOGARD, DSM COLLAGEN 1%, DSM COLLAGEN BOVINE 1%
Other
Products: PENTACARE-HP PF, PREREGEN® PF, COLHIBIN PF, STIMU-TEX® AS, ALL-Q (Coenzyme Q10) plus, PEPHA®-TIGHT, PENTAVITIN®, PEPHA®-CTIVE, PEPHA®-AGE, DSM ALPHA-ARBUTIN, DISMUTIN® PF, DSM ARGAN OIL, DSM ERYTHRULOSE, DSM HYALURONIC ACID-BT, HYDROLASTAN PF, HYASOL PF, IRICALMIN PF, DSM PHYTANTRIOL, LACTOMIDE, DSM SERICIN, ELHIBIN® PF, PEPHA®-PROTECT, MELAWHITE® PF, MELFADE® PF, PENTAGLYCAN PF, PHYTALURONATE® PF, REGU®-FADE, REGU®-SEB, REGU®-SCENCE, REVITALIN® PF, REGU®-SLIM, REGU®-STRETCH, SETAKOL® PF, REGU®-AGE PF, BEAUACTIVE®, Life’s GLA™ ‘10’ n-6 Oil, BEL-EVEN®, OXY 229 PF, PENTACARE-NA PF, Life’s GLA™ '25' n-6 Oil, CEPHALIPIN NP 2, DSM ALLANTOIN, LIPOGARD, DSM COLLAGEN 1%, DSM COLLAGEN BOVINE 1%

Formulations (1)

Formulation Name
End Uses
Product Families
Skin Care, Other Beauty & Care, Personal Care Formulations