DSM D-Panthenol

• Maintains a healthy skin: right balance between the stem cell renewal and the cell differentiation (p63 upregulated)
• Increases stratum corneum hydration by inducing long-lasting skin moisturization
• Reinforces the skin barrier by reducing transepidermal water loss (TEWL)
• Panthenol is produced with the highest standards in Dalry, Scotland a world-class DSM-owned facility honored with the CEFIC award for sustainable production processes
• Panthenol forms show very good compatibility with all groups of cosmetics ingredients

• Regenerates healthy skin maintaining cell stemness
• Improvement symptoms of sensitive skin:
• dryness, roughness, redness, pruritus
• Accelerates wound-healing
• Moisturizes hair, strengthens damaged hair and reduces split ends
• Reinforces the nails
• Improves hydration and maintain skin softness and elasticity

Panthenol is well absorbed into the skin and quickly converted into Pantothenic acid by oxidation. Pantothenic acid is distributed into the cells and is converted to Acetyl Coenzyme-A (Acetyl CoA) in the cells of the epidermis. Human being require Vitamin B5 to synthesize Acetyl CoA which is an essential mediator to many biochemical reactions that sustain life (maintenance and repair of all cells) and which breaks down fats, carbohydrates and proteins for carbon dioxide, water, and energy generation. Furthermore, it synthesis fatty acids and sphingolipids, for stratum corneum lipid layers and cell membrane integrity & fluidity.