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INCI Name: Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Magnesium Chloride
Function: Firming Agent, Moisturizing Agent, Humectant, Smoothing Agent
Ingredient Origin: Synthetic
Labeling Claims: BSE-free, Non-GMO, Not Tested on Animals, TSE-free, Preservative-free
Benefit Claims: Suppleness, Anti-Sagging, Moisturizing, Regenerating, Smoothing, Rejuvenating, Skin Protection, Skin Elasticity, Anti-Aging, Firming, Hydrating, Conditioning, Humectancy, Volumizing
Certifications & Compliance: EU Cosmetic Regulation 1223/2009 Compliant, REACH (Europe), Halal, IECIC (China)
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Safety Data Sheet
SYN® HYCAN Safety Data Sheet
SYN® HYCAN Safety Data Sheet
Safety Data Sheet

Knowde Enhanced TDS

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Identification & Functionality

SYN® HYCAN Features & Benefits

Product Highlights
  • Boosts skin's own renewal of hyaluronic acid
  • Does not contain intentionally added substances regulated / listed as presevative
  • Improves collagen fiber quality by increasing proteoglycan synthesis
  • Offers an effective solution for the two most desired benefits of hyaluronic acid moisture and skin volume enhancement
  • Patented tripeptide with low molecular weight
  • Urea Trifluoroacetate, Magnesium Chloride
Key Attributes
  • Provides skin volume and firming enhancement
  • Benefits on multiple skin zones (under eye, upper- and mid-cheek, jawline, neck)
  • Fuller, firmer skin is delivered in weeks
  • Skin is noticeably more supple, smooth, and moisturized

Applications & Uses

Mode Of Action
Proteins are involved in many physiological processes. Their broad acceptance as natural molecules, relatively high stability and well-defined actions have made them attractive for many skin-related indications, most notably in anti-aging therapy. Amongst them TGF-beta is a key protein, its proper activation is required for the synthesis of several highly relevant skin molecules such as Collagen and Glycosaminoglycans like HA. SYN®-HYCAN is a synthetic, patented tripeptide that mimics body's own mechanism to transform latent TGF-beta to its active form. This particular activation leads to increased skin's own synthesis of hyaluronan and stimulates the production of lumican and decorin, two important proteoglycans that are primarily responsible for maintaining a well-structured collagen matrix in the dermis.


Physical Form
Opalescent to hazy
Miscible In

Regulatory & Compliance

Storage & Handling

Shelf Life
36 months