DSM Vitamin B12
The biotech pink vitamin for sensitive and stressed skin. A naturally derived colorant skin care ingredient that relieves sensitive skin with a healthy looking skin. Consumer demand for clean, safe, and eco-conscious beauty care ingredients is set to accelerate. This new grade of vitamin B12 is produced through non-GMO bacterial fermentation, has a natural origin index of 68.7% and is Halal approved. As a popular cosmetic ingredient, the vitamin ingredient B12 will certainly give your products an on-trend pink hue. Our new studies show, it could help relieve fatigued and irritated skin, protect the skin barrier, and promote a more vibrant looking complexion.
Knowde Enhanced TDS
Identification & Functionality
DSM Vitamin B12 Features & Benefits
- Biotech naturally derived pink vitamin
- Active on atopic dermatitis, reducing erythema and pruritus in vivo
- Prevents inflammation ex vivo: significant and strong reduction of inflammasome and inflammatory cytokines such Il1-ß.
- Epigenetic regulation of inflammasome: over-expression by 61% of miR-22-3p with vitamin B12 at 0.01% leads to a reduction of inflammasome ex vivo
- Significantly reduction of Mast cell degranulation by 31%, drops the histamine release in vitro
- Vitamin B12 relieves sensitive and stressed skin
- Helps relieve skin conditions like itchy, irritated, inflamed, red and cracked skin
- Help Prevent photo-damaged skin
- Protects the skin barrier damage induced by inflammation
- Plays an important part in speeding up cell recovery and regeneration
- Skin looks more vibrant
- Provides a nice and pleasant pink color of the cosmetic products
Applications & Uses
Properties
Regulatory & Compliance
Technical Details & Test Data
UV, pollution, bacterial invasion or any oxidative stress induce the formation of the inflammasome, especially in keratinocyte. Its components are pro-Caspase-1, ASC and NLRP3 which is regulated by the epigenetic factor miRNA 22-3p. This inflammasome triggers and maintains the inflammatory response by cytokines production such as IL-1b. If it gets chronically activated, it causes skin irritation, skin tissue damage and premature aging.
