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DSM Vitamin B12

Sold by DSM
Supplier:  DSM
INCI Name: Cyanocobalamin
Ingredient Origin: Fermentation & Microorganisms, Natural Origin
Benefit Claims: Reduces Skin Damage, Vibrant Look, Cell Regeneration, Complexion, Relaxing, Skin Protection, Skin Barrier, Stress Reducing, Anti-Inflammatory, Anti-Itching, Suitable for Sensitive Skin, Irritation Reduction, Soothing, Anti-Aging, Anti-Fatigue, Easy To Use, Redness Reduction, Photo-Aging Protection, Prevents UV-Induced Erythema, Healthy-Looking Skin
Labeling Claims: Naturally Derived, Halal, Non-GMO, Natural, Clean at Sephora
Certifications & Compliance: Halal, ISO 16128, IECIC (China)
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DSM Vitamin B12
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Safety Data Sheet
DSM Vitamin B12 Safety Data Sheet
DSM Vitamin B12 Safety Data Sheet
Safety Data Sheet

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Identification & Functionality

Ingredient Origin
Cosmetic Ingredients

DSM Vitamin B12 Features & Benefits

Product Features
  • Biotech naturally derived pink vitamin
  • Active on atopic dermatitis, reducing erythema and pruritus in vivo
  • Prevents inflammation ex vivo: significant and strong reduction of inflammasome and inflammatory cytokines such Il1-ß.
  • Epigenetic regulation of inflammasome: over-expression by 61% of miR-22-3p with vitamin B12 at 0.01% leads to a reduction of inflammasome ex vivo
  • Significantly reduction of Mast cell degranulation by 31%, drops the histamine release in vitro
Product Benefits
  • Vitamin B12 relieves sensitive and stressed skin
  • Helps relieve skin conditions like itchy, irritated, inflamed, red and cracked skin
  • Help Prevent photo-damaged skin
  • Protects the skin barrier damage induced by inflammation
  • Plays an important part in speeding up cell recovery and regeneration
  • Skin looks more vibrant
  • Provides a nice and pleasant pink color of the cosmetic products

Applications & Uses

Personal Care
Application Format
Bath & Shower Applications
Hair Care Applications
Skin Care Applications


Physical Form

Regulatory & Compliance

Certifications & Compliance
Chemical Inventories

Technical Details & Test Data

Mode of Action

UV, pollution, bacterial invasion or any oxidative stress induce the formation of the inflammasome, especially in keratinocyte. Its components are pro-Caspase-1, ASC and NLRP3 which is regulated by the epigenetic factor miRNA 22-3p. This inflammasome triggers and maintains the inflammatory response by cytokines production such as IL-1b. If it gets chronically activated, it causes skin irritation, skin tissue damage and premature aging.