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SYN® AKE
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Producer: 
DSM
Brand: 
SYN
Stop wrinkling - Keep laughing. SYN® AKE is a small, patented, synthetic peptide that helps reduce the appearance of wrinkles and laughter lines - fast. As our skin gets older, the number of expression and laughter lines increases, along with crow's feet and forehead wrinkles. SYN® AKE enables the face to relax. It visibly reduces the appearance of wrinkles and expression lines. Thanks to its unique mode of action, SYN® AKE is fast acting and long lasting, with a fully reversible effect. SYN® AKE is a clear, colorless to yellowish, viscous liquid. For detailed regulatory or quality information, please contact the supplier.

SYN® AKE

Producer: 
DSM
Brand: 
SYN
Stop wrinkling - Keep laughing. SYN® AKE is a small, patented, synthetic peptide that helps reduce the appearance of wrinkles and laughter lines - fast. As our skin gets older, the number of expression and laughter lines increases, along with crow's feet and forehead wrinkles. SYN® AKE enables the face to relax. It visibly reduces the appearance of wrinkles and expression lines. Thanks to its unique mode of action, SYN® AKE is fast acting and long lasting, with a fully reversible effect. SYN® AKE is a clear, colorless to yellowish, viscous liquid. For detailed regulatory or quality information, please contact the supplier.
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Features & Benefits

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Origin
Synthetic
Product Highlights
  • Mimics Waglerin-1 functionality, a peptide found in the venom of the temple viper
  • Natural inspired mechanism
  • Preservative-free, glycerine-based aqueous solution
  • Safe for topical applications
  • Synthetic tripeptide with mol weight below 500 Da
  • Vegan-friendly
Key Attributes
  • Age-killing effect particularly effective against expression lines
  • Visible deep wrinkle smoothing after only 4 weeks
  • Helps your face to relax without losing the ability to express yourself
  • When used earlier in time, SYN®ï-AKE helps delaying the appearance of wrinkles, with age-freezing effect

Properties

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Ingredient Origin
Physical Form
Physical Form
Liquid
Color
Yellow
Appearance
Clear yellow liquid
Miscible In
Water
Insoluble in

Technical Details & Test Data

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Mode Of Action
  • SYN®-AKE is based on a patented mechanism. It mimics the essential amino acid sequence of the Waglerin-1 functionality.
  • Its effect focuses on an immediate and lasting relaxation of mimic wrinkles. In vitro the peptide cosmetic ingredient is considered as an antagonist at the muscular nicotinic acetylcholine receptor (mnAChR). As the muscular nicotinic ACh receptors are reversibly blocked, the ion channel remains closed. There is no uptake of Na+ and the muscle cells stay relaxed. The transmission of nerve impulses to the muscles is inhibited and facial muscles are relaxed.

Storage & Handling

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Shelf Life
48 months

Documents (6)

Name
Type
DSM Sustainability Imp’Act Card™
Other
Trends Vitamins for Healthy and Beauty Skins Vitamin B3
Other
Trends Vitamins for Healthy and Beauty Skins Vitamin E
Other
SYN® AKE Safety Data Sheet
Safety Data Sheet
DSM Personal Care Brochure
Other