Kalrez® 6221 perfluoroelastomer parts are a white product that provide superior chemical resistance and low contamination from extractables in pharmaceutical and food handling applications where FDA compliance is required. Kalrez® 6221 parts are especially suited for Water for Injection (WFI) systems, Steam-in-Place (SIP) cleaning and other critical systems. Kalrez® 6221 parts are thermally stable up to 260°C (500°F), permitting them to be used in Stage II Sterilization processes, where other elastomers lose their sealing ability. Kalrez® 6221 is available as O-rings. For white custom parts, please refer to Kalrez® LS205 parts.
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Identification & Functionality
Kalrez® 6221 Features & Benefits
Applications & Uses
Properties
| Value | Units | Test Method / Conditions | |
| Modulus (at 100% Elongation) | 7.2 | MPa | ASTM D 412 |
| Tensile Strength | 15.2 | MPa | ASTM D 412 |
| Elongation (at Break) | 150 | % | ASTM D 412 |
| Hardness (Shore A) | 70 | - | ASTM D 2240 |
| Compression Set (Pellet Type 1, at 204°C, 70h) | 27 | % | ASTM D 395B |
| Compression Set (O-Ring AS568-214, at 204°C, 70h) | 31 | % | ASTM D 1414 |
| Value | Units | Test Method / Conditions | |
| Maximum Service Temperature ¹ | 260 | °C | - |
| Lowest Service Temperature ¹ | -20 | °C | - |
| Value | Units | Test Method / Conditions | |
| Coefficient of Linear Thermal Expansion | 3.07 | E-4/°C | ISO 11359-1/-2 |
| Retraction Temperature (TR-10) | -4 | °C | ASTM D 1329 |
| Value | Units | Test Method / Conditions | |
| Density | 2.18 | g/cm³ | ISO 1183 |
- [1]: DuPont proprietary test method; useful temperature range may vary with seal design and application specifics
The overall chemical resistance of EPDMs, silicone elastomers and fluoroelastomers (FKM) is limited by their respective polymer structures. Kalrez® parts, on the other hand, offer the same universal chemical resistance as PTFE, but unlike PTFE, they have elastomeric properties, which help them maintain their sealing capa bilities. The following table lists the chemical compatibility of Kalrez® 6221 perfluoroelastomer parts and other elastomers used as sealing materials in the pharmaceutical and food handling industries
| Chemical Resistance |
Kalrez® 6221 |
EPDM | Si | FKM |
|---|---|---|---|---|
| Acetic Acid | A | A | A | B |
| Acetone | A | A | C | U |
| Citric Acid | A | A | A | A |
| Hydrogen Peroxide | A | B | B | B |
| Isopropyl Alcohol | A | A | A | A |
| Methyl Ethyl Ketone | A | A | U | U |
| Mineral Oil | A | U | B | A |
| NaOH | A | A | B | B |
| Nitric Acid | A | B | B | A |
| Sodium Hypochlorite | A | B | B | A |
| Soybean Oil | A | C | A | A |
| Steam (<150°C) | A | A | C | C |
| Steam (>150°C) | A | C | U | U |
| Toluene | A | U | U | A |
| Xylene | A | U | U | A |
| Maximum Service Temperature |
260°C (500°F) |
135°C (275°F) |
200°C (392°F) |
200°C (392°F) |
A = little or no effect
B = slight swelling and/or loss of physical properties
C = moderate to severe swelling and/or loss of physical properties/limited functionality
U = not suitable or recommended
Technical Details & Test Data
In aggressive pharmaceutical processing environments, seal failure from excess swelling, embrittlement, or decomposition can cause unscheduled downtime or product contamination. Elastomeric materials that come in contact with highly pure and aggressive water (e.g. WFI) must be chosen with care in order to prolong seal life. The perfluoroelastomer compounds used in Kalrez® parts have been shown to have extremely low, to non-detectable extractable levels in aggressive water systems. Because the perfluoroelastomer polymer in Kalrez® parts is fully saturated, it is also well suited for Ozonated Deionized Water service. Kalrez® parts also exhibit very low swell and loss of mechanical properties after repeated steam cycling.