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Eastman CAB-171-15NF Cellulose Acetate Butyrate
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Producer: 
Eastman
When cellulose is esterified with both acetyl and butyryl radicals to form the mixed ester, cellulose acetate butyrate, many of the desirable properties of both esters are obtained. Eastman™ Cellulose Acetate Butyrate CAB 171-15 National Formulary has the lowest butyryl content in the series of Eastman™ Cellulose Acetate Butyrates. It can be used as coating material as the semi-permeable membrane for osmotic drug delivery. It is also used for taste-masking and sustained release tableting. Eastman™ Cellulose Acetate Butyrate CAB-171-15 NF is made under cGMP and meets the requirements of the National Formulary (NF). Eastman™ Cellulose Acetate Butyrate CAB-171-15 NF is available in powder form.

Eastman CAB-171-15NF Cellulose Acetate Butyrate

Producer: 
Eastman
When cellulose is esterified with both acetyl and butyryl radicals to form the mixed ester, cellulose acetate butyrate, many of the desirable properties of both esters are obtained. Eastman™ Cellulose Acetate Butyrate CAB 171-15 National Formulary has the lowest butyryl content in the series of Eastman™ Cellulose Acetate Butyrates. It can be used as coating material as the semi-permeable membrane for osmotic drug delivery. It is also used for taste-masking and sustained release tableting. Eastman™ Cellulose Acetate Butyrate CAB-171-15 NF is made under cGMP and meets the requirements of the National Formulary (NF). Eastman™ Cellulose Acetate Butyrate CAB-171-15 NF is available in powder form.
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Features & Benefits

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Product Highlights
  • For use in coatings: semipermeable, excellent film former,strong, flexible.
  • Characteristics of coating can be modified (permeability, mechanical strength, flexibility) through blending two CAs or CA with CAB.
  • For use in tableting directly compressible, matrix for sustained release
  • CAB is more hydrophobic than CA.
  • Requires a solvent for coatings formulations
  • Modify a wide range of film properties through additives
  • Adjust sustained release by blending CA with CAB
  • Requires a solvent for coatings formulations
  • Modify a wide range of film properties through additives
  • Adjust sustained release by blending CA with CAB
  • Tablet formulated with CAB-171-15 NF exhibited a slower release rate compared to tablet formulated with CA-398-10 NF/EP.

Applications & Uses

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Recommended Uses
  • Personal care ingredients
  • Semipermeable membrane for osmotic drug delivery
    systems
  • Coating for extended-release tablets
  • Coating for taste masking
  • Binder to make tablets for sustained release via direct
    compression

Properties

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Physical Properties
ValueUnitsTest Method / Conditions
Solubility in WaterNegligible
Typical Properties
ValueUnitsTest Method / Conditions
ColorWhite--
Solubility in WaterNegligible--
Composition Acetyl28-31%
Composition Butyryl16.5-19%
Composition Hydroxyl0.8-1.4%
Composition Moisturemax 5wt %
Viscosity14-24Pa.sASTM A
Composition Hydroxyl0.8-1.4%-
Composition Moisturemax. 5.0wt %-
Composition Butyryl16.5-19%-
Composition Acetyl28-31%-
Viscosity14-24-ASTM A
Physical Form
Solid (powder)
Appearance
White
Insoluble in
Water

Storage & Handling

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Storage and Handling
  • Eastman cellulose esters are packed and sealed in fiber drums equipped with a polyethylene inner liner and reusable metal closure.
  • These containers should be sealed and protected from moisture or high humidity for extended periods.
  • Drums held in cool, dry storage should be brought to room temperature before opening to prevent condensation of moisture on inside surfaces.

Documents (16)

Name
Type
TENITE Cellulosic Plastics - Secondary Fabrication Techniques
Brochure
Cellulose ester blends for tunable drug delivery
Brochure
TENITE Cellulosic Plastics - Injection Molding
Other
Stress Measurement in Parts Made of Tenite Cellulosic Plastics
Other
Handling precautions for the use of cellulose esters in formulated products
Other