Sinetrol® is a natural combination of polyphenols extracted from citrus and guarana targeting body weight management. Sinetrol® reduces the excess of fat mass and improves long-term body composition.

Functions: Weight Management Ingredient

Active Component: Polyphenols

    Knowde Enhanced TDS

    Identification & Functionality

    Active Component
    Food Ingredients Functions
    Pharma & Nutraceuticals Functions
    Composition
    • Primary active compounds: naringin & hesperidin from citrus, both expressed as flavanones > 40%
    • Secondary active compounds: other flavanones, caffeine

    Features & Benefits

    Benefit Claims (Health)
    Food Ingredients Features
    Product Highlights
    • Patented ingredient
    • Proven mechanism of action: adipose beiging benefits
    • Increase in resting energy expenditure
    • Rebalanced body composition: significant reduction of body fat mass without lean mass loss
    • Significant result on body weight, waist and hip lines
    • Long-lasting benefits: Subjects continue to experience adipose beiging benefits

    Applications & Uses

    Use Level
    630
    Mechanism of Action

    More than 10 years of research have been conducted to support the mechanism of action and clinical benefits of Sinetrol® on body composition.

    Sinetrol® works at the adipocyte level :

    The action of Sinetrol® relies on its patented mechanism of action on the physiological energetic pathway of lipolysis. Sinetrol® mimics adipose cell phenotype change from white to beige, i.e. from a storing category of adipose cells to an energy metabolism-driven adipose cell category.

    This effect of Sinetrol® avoids further restorage of fat within adipose tissue.

    Technical Details & Test Data

    Clinical Studies

    Sinetrol® is a patented ingredient studied in over 300 subjects in 4 clinical studies including both Caucasian and Asian populations. Its benefits have been demonstrated using gold-standard methodology during interventional studies with follow-up.