Knowde Enhanced TDS
Identification & Functionality
- Carrier
- Chemical Family
- INCI Name
- Ingredient Origin
- Cosmetic Ingredients Functions
- Technologies
- Product Families
- Product Origin
- Natural Hinokitiol extracted from sawdust of Aomori Hiba. (Thujopsis dolobrata (Thunb. ex L. f.) Siebold & Zucc.).
- The Asunaro (or Thujopsis dolobrata) is a ornamental tree from Japan. It is used to a small extent in forestry in Japan, grown for the valuable wood, which is durable and scented.
- Natural Levulinic acid is obtained by fermentation of sugar cane.
Features & Benefits
- Benefit Claims
- Labeling Claims
- Product Features
- Anti-Microbial synergistic effect
- Anti-aging from Hinokitol
- Natural preservative booster
- High penetration of Hinokitol (anti-aging function) with Levulinic acid.
- Effective anti-inflammatory reagent
- May cure hair loss
- Product Pathway
- By inhibiting Wnt/beta-catenin signaling pathway
- Inhibitory effect of beta-thujaplicin on UVB induced apoptosis
- Inhibits TNF-alpha production in LPS-activated macrophages via suppression of NF-kappaB
- Product Benifits
- Anti-aging
- Anti-acne
- Adaptable to sensitive skins with blemish
- Natural preservation boosting
Applications & Uses
- Markets
- Applications
- Application Format
- Hair Care Applications
- Use Level
- 2-3 %
- Recommended Uses & Known Applications
- For oily hair
- For acne skin, sensitive skin
- Natural preservation booster
Properties
- Physical Form
- Appearance
- Light yellow liquid
- Odor
- Characteristic Odor
- Soluble in
- Water
- Typical Properties
- Microbiological Values
| Value | Units | Test Method / Conditions | |
| pH | 5 - 6 | — | — |
| Yeast & Mold | max. 100 | CFU/g | NF EN ISO 16212 |
| Escherichia coli | Absence in 1 g | — | NF ISO 21150 |
| Staphylococcus aureus | Absence in 1 g | — | NF ISO 22718 |
| Pseudomonas aeruginosa | Absence in 1 g | — | NF ISO 22717 |
| Candida albicans | Absence in 1 g | — | NF ISO 18416 |
| Hinokitiol | 1.5 ± 0.1 | % | HPLC |
| Candida Albicans | Absent | 1g | NF ISO 18416 |
| Escherichia Coli | Absent | 1g | NF ISO 21150 |
| Pseudomonas Aeruginosa | Absent | 1g | NF ISO 22717 |
| Value | Units | Test Method / Conditions | |
| Total Plate Count | max. 100 | CFU/g | NF ISO 21149 |
Regulatory & Compliance
- Certifications & Compliance
Technical Details & Test Data
- Anti-ageing Properties
Hinokitiol acts as a chelators of ions. It has anti-aging at three levels :
- by acting on the extracellular matrix by inhibiting MMPs
- by stimulating SOD and Catalase
- by inhibiting a series of pro-inflammatory cytokines.
Levulinic acid has been used to enhance permeation of several drugs.
It is known to influence stratum corneum lipid structures and cell permeability.
Storage & Handling
- Shelf Life
- 24 months
- Storage and Handling
Storage
In a dark, dry and fresh place.
Precautions for safe handling
- Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
- Avoid exposure - obtain special instructions before use.
- Provide appropriate exhaust ventilation at places where dust is formed.
- Normal measures for preventive fire protection.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.