Novyrate® EB is a premixture. It is a synergetic combination of mono-, di-, and tri-esters of butyric acid, with immediate activity in the early part of the intestinal tract and a prolonged effect towards the hindgut.

Ingredient Name: Esterified Butyric Acid

Functions: Digestion Promotor

Animal Species: Broilers, Calves, Laying Hens, Pets, Piglets, Swine, Turkey

Features: Antibiotic Growth Promoting Alternative, Free-Flowing, Improves Digestability & Intestinal Health, Promotes Digestive Health, Promotes Healthy Gastrointestinal Environment

Technical Data Sheet
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Identification & Functionality

Animal Feed & Nutrition Functions
Ingredients
Esterified Butyric Acid
Components

Butyric acid esterified with glycerol into mono-, di-, and triglycerides of butyric acid, anticaking agents and carrier.

Features & Benefits

Product Background
  • The increasing animal genetic potential puts a significant stress on the animals’ digestive system, often leading to a suboptimal digestive process and nutrient absorption.
  • The negative impact of sub-optimal feed utilization has a significant impact on the economic viability of the farm. Butryic acid contributes to a healthy intestinal environment. The esteriefied forms have a release in the lower part of the digestive tract. Tri-esters will supply significant amounts of butryic acid after hydrolysis by lipase, while mono-butyrin is an important component that can help to balance and stimulate a healthy intestinal microflora.
  • Nowadays genetic potential of monogastric farm animals allows the animals to grow faster by using less feed. To perform up to this genetic potential the nutritional quality of the diets needs to meet the animal’s requirements. Particularly the diets fed during the first phases in the animal’s life are very important.
  • First phase feeding will have a significant impact on the intestinal bacterial community and the development of the intestinal structure, integrity and functionality. A sub-optimal intestinal functionality during this first phase has a significant and negative impact on the animal performance up till the end of the growing period. In order to maximize the genetic potential of the animals, Novyrate will act as an essential nutrient for the development and maintenance of digestive functionality and integrity.

Applications & Uses

Use Level
0.75 - 2 kg/T (Piglets), 1 - 2 kg/T (Sows), 0.5 - 0.75 kg/T (Layers & breeders), 1 - 3 kg/T (Aquaculture), 0.25 - 0.75 kg/T (+25 kg pigs), 0.25 - 1 kg/T (Broilers), 0.5 - 1 kg/T (Turkeys), 1 - 3 kg/T (Pets)

Properties

Physical Form
Appearance
Free flowing powder
Physical Properties
ValueUnitsTest Method / Conditions
pH (in 10% Solution)6.2 - 7.2
Specific Gravity0.64 - 0.74kg/l
Moisture Contentmax. 5%Karl Fischer Method
Butyric Acid Content39.6 - 48.4%

Technical Details & Test Data

Pretreated Spectra

Novyrate® EB - Pretreated Spectra

Modes of Action

Butyrate has mainly been used as a direct energy source. Research has now produced evidence that specific metabolic effects can be attributed to butyrate making it an important and useful metabolic molecule in animal feeding.

  1. Butyrate is normally rapidly absorbed and arrives in the bloodstream:
    • Stimulating growth of villi.
    • Stimulating function of liver cells.
  2. Butyrate when delivered in the lower part of the intestinal tract, attaches to specific receptor cells which have shown to release peptides that:
    • Stimulate the ability of the animal to overcome bacterial infections.
    • Slow down the emptying of the stomach/gizzard to optimize feed passage.
    • Increase the absorption of electrolytes and water, providing dryer manure.
    • Decrease the adsorption of ammonia, thereby reducing the toxic effects in the animal.
    • Increase pancreatic secretion, improving digestive processes
    • Increase entero-endocrine activity
    • Improve vascular intestinal supply
  3. The same type of receptors is found in spleen, bone marrow and monocytes, suggesting that butyric acid will affect positively the immune system as well.
  4. Many research work as well as field experience have demonstrated the beneficial effect of using Butyrate combined either with other organic acids and/or essential oils and botanicals. Such combinations can prove to be more effective than using any single material alone.
Target Release
  • Butyric acid is most active when it reaches the lower parts of the intestinal tract, ensuring the animal benefits from its antipathogenic as well as its additional metabolic and physiological effects. Encapsulated butyric acid is therefore preferred over the uncoated one.
  • This not only prevents odor, but also helps to ensure that butyric acid is released at the right place and in a sustained manner. The encapsulation - also known as coated butyric acid - travels down the gut line and gets released gradually in the small intestine. The secretion of lipase in the beginning of the small intestine allows the gradual release of the organic acids throughout the digestive tract, but especially in the small and large intestine. It makes a sustained and slow release till the hindgut of the intestines.
  • The next generation of this molecule is esterified butyric acid. Esterifie­­d butyrins are combined molecules of glycerol and butyrate where the end product is mono-, di- and tri-esters which act as a source of butyric acid, with the help of lipase. They do not require coating and can pass through the upper gastro-intestinal tract to release butyric acid in the small intestine, after separation, with the help of pancreatic lipase. Due to the similarity with tri-glycerides, these esters also bypass the stomach and the end result is like that of a coated butyrate. Unlike organic acids, esters are not pH dependent.
  • Either of the two variants of butyric acid – Coated Sodium Butyrate or Esterified Butyrin serve as a good substitute for antibiotic growth promoters (AGPs). In today’s highly genetic potential of production in birds, coupled with restricted usage of antibiotics - these multifunctional molecules serve as a boon to the industry. The critical factor is the form in which butyric acid is being supplemented. This will determine the profits it will carry, right from the start till the end of rearing.

Packaging & Availability

Packaging Type
Packaging Information
  • Standard 25 kg export worthy bags on wooden fumigated pallets.
  • Other net weights (1 kg*, 5 kg*, 10 kg, 20 kg, 750-1000 kg, bulk) on demand.

*Marked unit packs are packed in an outer carton up to max. 25 kg.

Storage & Handling

Shelf Life
2 Years
Storage Conditions

2 years when stored in a cool, well ventilated and dry environment out of direct sunlight in unopened packing.