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Cosmocil® CQ

Cosmocil® CQ is a mild, water-soluble, broad spectrum, fast-acting bactericide that is heat and UV stable. A 20% aqueous solution of poly(hexamethylenebiguanide) hydrochloride, also known as PHMB, it is an effective preservative for make-up removers, moisturizing toners, facial cleansers, wet wipes and also offers antibacterial and deodorant properties.

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Technical data sheet (TDS)
Product brochure
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Properties

Features And Benefits
Summary
Clear, Colorless
Highly Water-soluble
Fast-acting and strong antibacterial efficacy
High activity vs. tough gram (negative) organisms e.g.Pseudomonas
Chemically stable and non-volatile
Zero VOC
Effective and stable over a broad pH range (3-10)
UV stable
Odorless and non-foaming
Broad global acceptance
Non-sticky feel on the skin
Free from smell and taste
End Use Claims
Anti-microbial
Regional Availability
North America
Europe
Asia Pacific
Regulatory Status
REACH Listed (Europe)
China Compliant
Product Characteristics
Origin
Chemical Synthesis
Physical Form
Liquid
Color
Colorless
Odor
Odorless
Appearance
Clear
Formulation Conditions
Use Level
0.2-1.5%
Soluble in
Water
Miscible In
Water
Ethanol
Glycerin
Propylene glycol
Application pH Range
3–10

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Technical product information

Key Attributes
  • Fast-Acting and Trusted Antibacterial
  • Clear, colorless, highly water-soluble
  •  Fast-acting and strong antibacterial efficacy
  • High activity vs. tough Gram (negative) organisms e.g. Pseudomonas
  • Chemically stable and non-volatile
  • Zero VOC
  • Effective and stable over a broad pH range (3-10)
  • UV stable
  • Odorless and non-foaming
  • Broad global acceptance
  • Non-sticky feel on the skin
Description

Cosmocil® CQ is a broad spectrum, fast-acting antibacterial. A 20% aqueous solution of poly(hexamethylenebiguanide) hydrochloride, also known as PHMB, Cosmocil® CQ is an effective preservative for personal care formulations, active against a wide range of both Gram-positive and Gram-negative bacteria.

Compositional Breakdown

 

Applications
  • Baby care
  • Baby wipes
  • Body wash
  • Conditioner
  • Cream
  • Deo/ Anti-perspirant
  • Eye creams/gels
  • Eye shadow
  • Face lotion
  • Face wipes
  • Facial cream
  • Foundation
  • Hair gel
  • Hand soap (non anti-bac)
  • Lipstick/gloss
  • Lotion
  • Make-up remover
  • Mascara
  • Oil in Water
  • Oral care (as preservative, not the active)
  • Powder
  • Shampoo
  • Suncare
  • Toner
  • Water in Oil
Efficacy

Microbiological Challenge Studies

Studies were run on three formulas at two concentrations of Cosmocil® CQ. The protocols used were the CTFA challenge test (56-day study with reinoculation at Day 28) and the EP challenge test (28-day).

Skin Cleanser Formulation

Skin Cleanser Test Result pH 6.7 – 28-day EP protocol : 0.4% Cosmocil® CQ

Lotion Formulation

Lotion Test Results pH 5.4 – 56-day CTFA protocol : 0.5% Cosmocil® CQ

Lotion Test Results pH 7.6 – 56-day CTFA protocol: 0.5% Cosmocil® CQ

Lotion Test Results 56-day CTFA protocol : Unpreserved control

Make-Up Remover Formulation

Make-Up Remover Test Results pH 5.5-56-day CTFA protocol: 0.5% Cosmocil® CQ

Make-Up Remover Test Results pH 7.8-56-day CTFA protocol: 0.5% Cosmocil® CQ

Make-Up Remover Test Results 56-day CTFA protocol: Unpreserved control

Global Regulatory

Europe

  • Polyaminopropyl biguanide is listed on the Annex V to Regulation
    EC/1223/2009 – formerly Annex VI to Council Directive 76/768/EEC
    relating to preservatives for use in cosmetic products
  • Max authorized use level of 0.1% PHMB as a preservative

Japan

  • Approved for all categories of cosmetic products (leave-on, rinse-off
    and mucous contact) at a maximum dosage of 0.1% PHMB

United States

  • Allowed for Personal Care Products
Formulation Recommendations
  • If additional antifungal activity is required, Cosmocil® CQ can be
    formulated alongside the likes of sorbic acid, benzoic acid or IPBC
  • Since the active agent PHMB is cationic, the compatibiility and
    efficacy in anionic systems may be impacted

Other Products within this Brand (2)

Complete your formula with these ingredients

Branded product

Cosmocil® PG Antimicrobial

INCIs: Polyaminopropyl Biguanide

Categories: Functional Actives Microbial Control & Preservation

412 Mt. Kemble Avenue
Morristown, NJ 07960
United States