Lonza

Lonzaserve® PC

Lonzaserve® PC is a synergistic preservative system with dual broad spectrum activity for maximum preservation. It is effective against formaldehyde and isothiazolinone resistant organisms, Gram-positive and Gram-negative bacteria, fungi and yeast over a broad pH range. It is a colorless liquid with a very safe toxicology profile that is compatible for use in most personal care formulations.

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Documents

Technical data sheet (TDS)
Product brochure
See all documents (3)

Properties

Features And Benefits
Summary
Aqueous, non-freezing blend
Colorless liquid preservative
Ultra-low free formaldehyde (< 0.09 %)
Broad spectrum efficacy
Ease of handling
Compatible and soluble in virtually all raw materials
Stable, synergistic, patented blend
Low isothiazolinone levels in end products (< 1 ppm)
Safe toxicology profile
Effective against formaldehyde and isothiazolinone resistant organisms
Neutral pH
Color stability
End Use Claims
Preservation
Regulatory Status
China Compliant
Regional Availability
North America
Europe
Product Characteristics
Physical Form
Liquid
Color
Colorless
Odor
Mild
Formulation Conditions
Use Level
0.05 – 0.2 %
Soluble in
Water
Ethanol (20 °C)
Application pH Range
3–9

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Technical product information

Key Attributes
  • Stable, synergistic, patented blend
  • Colorless liquid preservative
  • Low isothiazolinone levels in end products   (< 1 ppm)
  • Ultra-low free formaldehyde (< 0.09 %)
  • Safe toxicology profile
  • Broad spectrum efficacy
  • Neutral pH
  • Effective against formaldehyde and isothiazolinone resistant organisms
  • Color stability
  • Ease of handling
  • Compatible and soluble in virtually all raw materials
  • Aqueous, non-freezing blend
Compositional Breakdown

Applications
  • Anhydrous
  • Body wash
  • Conditioner
  • Cream
  • Deo/Anti-Perspirant
  • Eye creams/gels
  • Eye shadow
  • Face lotion
  • Face wipes
  • Facial cream
  • Foundation
  • Hair gel
  • Hand soap (non anti-bac)
  • Lotion
  • Makeup remover
  • Mascara
  • Oil in Water
  • Powder
  • Shampoo
  • Sun Care
  • Toner
  • Water in Oil
Efficacy

Studies were run using different concentrations of Lonzaserve® PC in various formulations to see efficacy against various bacteria, yeast and fungi. All samples were inoculated at the beginning of the study, sampled at 7, 14, 21 and 28 days.

Anionic Protein Shampoo

pH: 7

Test Results

Percent of Lonzaserve® PC required to achieve < 10 cfu/g ofmixed bacteria in anionic shampoo

Percent of Lonzaserve® PC required to achieve < 10 cfu/g ofmixed fungi in anionic shampoo

Non-Ionic Cream

pH: 6

Test Results

Percent of Lonzaserve® PC required to achieve < 10 cfu/g of mixed bacteria in a nonionic cream

Percent of Lonzaserve® PC required to achieve < 10 cfu/g of mixed fungi in a nonionic cream

Formulation Recommendations
  • Readily soluble in aqueous phase, as well as in polar organic solvents
  • Reducing agents, amines and strong nucleophiles will reduce activity of MCI/MI
  • When used with amines, pH should be below 6 before addition
  • Surfactants should be checked for residual bisulfite before addition
  • Should be added during the cool down phase of processing, at temperature of 50°C or below
  • pH: 3–9
Global Regulatory

Europe

  • Not permitted for leave-on products. Maximum use level of 0.0015 % CMI/MI for rinse-off applications

Japan

  • Max use level of 0.3 % DMDMH and 0.01 % CMI/MI for rinse-off
  • Not permitted for leave-on due to CMI/MI

US

  • Max use level of 0.6 % DMDMH and 0.00075 % CMI/MI for leave-on
  • Max use level of 0.6 % DMDMH and 0.0015 % CMI/MI for rinse-off

Other Products within this Brand (2)

Complete your formula with these ingredients

Branded product

Lonzaserve® ID

INCIs: Methylchloroisothiazolinone Methylisothiazolinone DMDM Hydantoin

Categories: Microbial Control & Preservation

412 Mt. Kemble Avenue
Morristown, NJ 07960
United States