Nanovetores Tecnologia S.A. Symbiocaps LA

Symbiocaps LA is a encapsulated active ingredient in biopolymer particles with a diameter larger than 200nm. The encapsulation through the technology developed by Nanovetores allows the stabilization of sensitive components, therefore, complex of being formulated in their free form, providing to the product high efficiency in restoring immunity and moisturizing the skin, combating aging and protecting external aggressions, and contributing to the treatment of acne and rosacea.

INCI Name: Algin, Calcium Chloride, Lactobacillus, Potassium Sorbate, Sodium Benzoate

Functions: Anti-Acne Agent, Anti-Aging Agent, Anti-Inflammatory, Moisturizing Agent, Protective Agent

Labeling Claims: Clean at Sephora, Cruelty-Free, Halal, Not Tested on Animals

Certifications & Compliance: Halal, ISO 9001

Benefit Claims: Anti-Acne, Anti-Aging, Anti-Inflammatory, Couperose Reduction, Encapsulated Actives, Hydrating, Invigorating, Moisturizing, Oil Control, Pore Refining, Redness Reduction, Regenerating, Rejuvenating, Skin Microbiome, Softening, pH Balancing

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Knowde Enhanced TDS

Identification & Functionality

Carrier

Features & Benefits

Product Information

The human body is inhabited by a microscopic world living harmoniously, contributing to the proper functioning of our organism. Skin, for example, is inhabited by about a thousand different species of bacteria, keeping this ecosystem stable by controlling its pH and temperature. Changes in skin pH, for example, are associated with dermatological conditions such as dermatitis, Acne vulgaris and infections caused by Candida albicans.

Probiotics are living microorganisms that, when administered in enough quantity, provide a health benefit, according to the World Health Organization. These microorganisms have the smart ability to reconstruct and strengthen the skin barrier, protecting it from pathogenic (disease-causing) organisms through courses of action:

  • By antagonism; competing for nutrients or space (setting area) and producing antimicrobial substances such as lactic acid, for example.
  • Inhibiting pathogenic action; reducing damage resulting from the action of bacterial toxins. Here, the probiotic Lactobacillus Acidophilus stands out.Nanovetores Tecnologia S.A. Symbiocaps LA - Product Information

Figure 1: Schematic drawing representing the microbiota.

Bacteria belonging to the Lactobacillus genus have characteristics similar to lactic acid bacteria: Gram (+) bacilli or cocci. Lactobacilli are found in the mucosa of humans and animals, plants and in rich substrates containing available carbohydrates and in fermented foods.

Although the use of probiotics is already widespread in foods such as yogurts and food supplements, a new era of interest transforming the use of appropriate and beneficial probiotics in cosmetic products has emerged in the world of beauty and skin health. The benefits of using probiotics in the cosmetics industry are many and mainly focus on the well-being and appearance of the skin. There are many benefits of the continuous use of probiotics in cosmetics, such as intensive treatment of enlarged pores, invigorating skin hydration and high restoration of its immunity, which provides active protection against external aggressions. Other benefits of probiotics in cosmetic products include regulating the skin's pH, reducing the level of skin inflammation, regenerating cell metabolism and fighting the aging process; focused on softening and leaving the skin looking healthy and soft.

Current research on the complex interaction between the microbiota, barrier function and the innate immune system of the skin indicates that the skin microbiota plays a beneficial role, much like the intestinal microflora. Preservation of microflora, maintaining and/or restoring healthy skin microbiota has become the goal of modern therapies. Pre and probiotics have been suggested as important applications of such therapies and, in recent years, they have reached scientific popularity as safe and effective agents for regulating skin health and microenvironment.

The encapsulation of probiotics aims to promote greater protection of these microorganisms and their viability, ensuring their better performance in the skin.

Nanovetores Tecnologia S.A. Symbiocaps LA - Product Information - 1

Figure 2: Image of encapsulates LAs. Source: Nanovetores.

Product Features

Particle: Biopolymer

Release Trigger: Enzyme

  • Treatment of acne and rosacea
  • Pore minimization
  • Refreshing moisturizing of the skin
  • Prevents skin aging
  • Regulates pH and microbiota of the skin
  • Protection against external factors
Unique Benefits of Nanovectores Encapsulation Technology
  • Multifunctional Lipid Particles that promote hydration and extended effect
  • Active Ingredient Protection against oxidation resulted from interaction with external environment and other components of the cosmetic formulation
  • Monodispersity, that ensures control of the particle size, providing adequate permeation to its proposed action
  • Secure particles larger than 200nm, biocompatible and biodegradable
  • Enzymatic Specific Release Trigger, where enzymes present on the skin disintegrate particles, releasing the active ingredient specifically where it needs to act
  • Greater Permeation on the contact surface due to the small size of the capsule
  • Surface Charge Control of the particle, promoting greater affinity with the contact surface
  • Water Base. Active ingredients are manufactured without the use of organic solvents, ensuring safety for users and the environment
Encapsulated Active Ingredients Benefits
  • Stability Improvement
  • Use of sensitive active ingredients (without refrigeration)
  • Increased Solubility
  • Prolonged release
  • Increased effectiveness
  • Increased compability in the formulation
  • Occlusion of odors
  • Increased skin permeation
  • Reduced dose

Applications & Uses

Color Cosmetic Applications
Treatment Product Applications
Use level
2.0-15.0%
Recommended Uses

Primers, creams, serums, emulsions, gels

Properties

Physical Form
Odor
Characteristic
Appearance
Milky liquid
Typical Properties
ValueUnitsTest Method / Conditions
Relative Density0.9 - 1.1g/ml
pH Value3.5 - 6.5
pH Value Stability3.0 - 7.0

Regulatory & Compliance

Certifications & Compliance

Technical Details & Test Data

Efficacy Studies

Effectiveness Screening

Evaluated Product: Serum com Symbiocaps LA.

Goal: Determine the activity of the products regarding the potential of hydration, aging, reduction of acne, rosacea and dilated pores.

Source: Nanovetores – Study conducted with 13 volunteers, with ages between 18 and 48 years old, during 30 days using Serum with Symbiocaps LA, twice a day.

Potential Anti-aging

Nanovetores Tecnologia S.A. Symbiocaps LA Efficacy Studies - 1

Acne Reduction

Nanovetores Tecnologia S.A. Symbiocaps LA Efficacy Studies - 2

Effectiveness Screening

 

Rosacea Reduction

Nanovetores Tecnologia S.A. Symbiocaps LA Efficacy Studies - 3

Reduction of Pore Dilation

Nanovetores Tecnologia S.A. Symbiocaps LA Efficacy Studies - 4

Conclusion: By perceived efficacy during the sensory evaluation it was possible to conclude that there was significant improvement in hydration (average increase of 42.60%) and skin appearance, potential reduction of expression lines, as well as acne, rosacea and dilated pores.

Storage & Handling

Storage and Handling

Keep at room temperature between 20 AND 25 °C.