CELLETS

PHARMATRANS SANAQ AG Brand

Products:10

Pellets made of Microcristalline Cellulose for retard formulations and innovative drug delivery. According to monographs of Microcrystalline Cellulose (Ph. Eur., USP-NF). DMF N° 18519 since July 15, 2005.

A homogeneous distribution of the active agend and the controlled release are two fundamental advantages of this dosage form.

Multiple dosage form mean more reliable formulations thanks to the homogeneous concentration of highly active agents. CELLETS® support this pioneering development. We can supply this innovative pellet in almost any particle size starting from 100 µm micropellets.

View All CELLETS Products

Knowde Brand Summary

Identification

Pharma & Nutraceuticals Functions

Features & Benefits

Applications & Uses

Application Format
Bath & Shower Applications
Home Care Applications

Knowde Brand Highlights

Cellets. The safe and easy way to multi-particular dosage forms

Multi-particular dosage forms have striking advantages compared to monolithic dosage forms, such as:

  • low variability of gastric emptying
  • low dependency on nutrition state
  • low risk of localized high drug concentrations in the GI
  • reduced risk of sudden dose dumping
  • lower intra- and inter-individual variability
  • high control on time and place of drug delivery

Altogether, this means higher safety and better compliance for your patients, and added-value for your products.
However, historically the way to successful formulation of multiparticular dosage forms was bumpy.
But: Cellets with their unique features NOW offer streamlined formulation and processing opportunities, making formulator’s life easier, and your patient ́s lives more safe.

Advantages
  • Micropellets (100 – 200 µm) for highly active low dosage API.
  • Perfect tool for combinatory and controlled release products.
  • Wide range of particle size fractions with uniform spherical shape and structure.
  • Narrow particle size distribution within each fraction.
  • CELLETS® are made under GMP conditions using MCC from certified suppliers only.
  • Formulation of sensitive actives due to the inertness of MCC.
  • High abrasion resistance improves the coating process.
  • Excellent compactability due to the high plasticity of the CELLETS®, for formulation of multidosage tablets.
  • Higher payload permits smaller capsule sizes.
 
Processing Advantages

The specific manufacturing process of Cellets provides mechanically extremely stable cores.
Low friability and solubility facilitates the layering process and improves the yield while the extreme hardness of the core makes Cellets a perfect carrier for later tabletting.
Cellets 100 provide the same core quality in sphericity and stability as coarse fractions and therefore grant comparable content uniformity and constant release profiles.

Content Uniformity and Controlled Release

The homogeneous distribution of APIs in multiparticular dosage forms make high demands on core material characteristics:

  • narrow particle size distribution
  • even and dense surface
  • perfect sphericity
  • low friability
  • inertness

Altogether, this means higher safety and better compliance for your patients, and added-value for your products.

Neutral Cores

As an inert odorless and tasteless excipient MCC is extremely versatile.
Cellets are made from certified MCC and pure water allowing you to multiply the benefits of neutral pellets with the unbeatable properties of MCC.

The Advantages at a Glance
  • Micropellets (100 μm - 200 μm) for highly active low dosage API
  • Perfect tool for combinatory and controlled release products.
  • Wide range of particle size fractions with uniform spherical shape and structure.
  • Narrow particle size distribution within each fraction.
  • Cellets® are made under GMP conditions with MCC from certified suppliers.
  • Quality analysed according to Ph. EU., USP/NF and JPE.
  • Formulation of sensitive actives due to the inertness of MCC.
  • Cellets® are water insoluble.
  • High abraison resistance improves and simplifies the coating process.
  • Ideal for capsules.
  • Cellets® show excellent compactability due to the high plasticity of Cellets®.
  • Higher payload permits smaller capsule sizes.