CELLETS® 500 has shorter and more stable layering process with high yields due to low friability and non-solubility in comparison to standard starter cores.

Chemical Name: Cellulose, Microcrystalline

CAS Number: 9004-34-6

Functions: Carrier, Controlled Release Agent

Dosage Form: Capsules, Pellets, Sachets, Tablets

Labeling Claims: BSE-free, Naturally Derived, TSE-free

Certifications & Compliance: European Pharmacopeia (Ph. Eur.), Japan Pharmacopeia (JP), National Formulary (NF), United States Pharmacopeia (USP)

Synonyms: Crystalline cellulose, Micro Fibril Cellulose, Pyrocellulose

Similar Products

  • TypeDocument Name
View All Documents

Knowde Enhanced TDS

Identification & Functionality

Pharma & Nutraceuticals Functions
CAS No.
9004-34-6
EC No.
232-674-9

Features & Benefits

Product Highlights
  • Produced of pure MCC
  • Highly spherical and narrow particle size for reproducible production and content uniformity.
  • Shorter and more stable layering process with higher yield due to lower firability non solubility in comparision with standard starter core.

Applications & Uses

Home Care Applications
Applications
  • These are used as neutral starter cores for controlled release formulations.
  • Used in capsule and tablet formulations.
     

Properties

Physical Form
Odor
Odorless
Appearance
White or nearly white or beige, hard and almost spherical particles
Insoluble in
Water, Ethanol, Acetone, Toluene, Diluted acids Ph.Eur., Sodium hydoxide solution (50 g/l)
Physico-Chemical Properties
ValueUnitsTest Method / Conditions
Particle Size500 – 710μmCellets Standard
Loss on Dryingmax. 7.0%Ph. EUR / USP/NF / JP / JPE
Bulk Density7.95 - 8.05g/cm³Ph. EUR / USP/NF / JP
Friability0%Cellets Standard
Swelling Indexmax. 2ml/gCellets Standard
Sphericity Degree (average)max. 0.9Cellets Standard
pH Value5.0 - 7.5Ph. EUR / USP/NF / JP / JPE
Conductivitymax. 75μS/cmPh. EUR / USP/NF / JP / JPE
Ether Soluble Substancesmax. 0.05%Ph. EUR / USP/NF / JP / JPE
Water Soluble Substancesmax. 0.25%Ph. EUR / USP/NF / JP / JPE
Residue on Ignitionmax 0.1%Ph. EUR / USP/NF
Microbiological Values
ValueUnitsTest Method / Conditions
TAMCmax. 1000CFU/gPh. EUR / USP/NF / JP / JPE
TYMCmax. 100CFU/gPh. EUR / USP/NF / JP / JPE
E. Coli, Ps. Aeruginosa,st. AureusNegative in 10 g samplePh. EUR / USP/NF / JP / JPE
Salmonella SpeciesNegative in 10 g samplePh. EUR / USP/NF / JP / JPE
Composition
ValueUnitsTest Method / Conditions
Heavy Metals10ppmJP / JPE

Regulatory & Compliance