TAP® 700

Identification & Functionality

Chemical Name

Tartaric Acid

Food Ingredients Functions

Acidulant,

Buffers & pH Stabilizer,

Sequestering Agent

Pharma & Nutraceuticals Functions

Buffers & pH Stabilizer,

Solubilizer

CAS No.

526-83-0

EC No.

610-885-0

Technologies

Food Ingredients,

Pharmaceuticals & Nutraceuticals

Product Families

Pharmaceuticals & Nutraceuticals — Excipients

Formulation & Processing Aids,

Solvents & Solubilizers

Food Ingredients — Functional Additives

Acidulants & Acidity Regulators,

Antioxidants & Preservatives

Features & Benefits

Labeling Claims

BSE-free,

Non-Irritant,

Non-Toxic,

TSE-free

Food Ingredients Features

Solubilizing

Characteristics

• Certain API show pH dependent solubilty which can be a hurdle in the fomulation of extended release dosage foms.
• TAP acts as a pH modifier for substances (weakly basic drugs) with a poor solubility in higher pH that occur in the lower GIT.
• TAP enhances the solublity in this environment.

Applications & Uses

Markets

Food & Nutrition,

Healthcare & Pharma

Applications

Food & Nutrition — Beverage

Other Non-Alcoholic Beverages

Healthcare & Pharma — Drug Delivery & Care Solutions

Oral,

Parenteral,

Topical

Food & Nutrition — Food

Confectionery

Food & Nutrition — Nutrition & Well Being

Nutraceuticals & Supplements

Dosage Form

Granules,

Tablets

Food & Nutrition Applications

Confectionery Products

Properties

Physical Form

Pellets,

Solid

Appearance

White or nearly white or beige particles

Chemical Properties

	Value	Units	Test Method / Conditions
Appearance of Solution	Clear and not more intensely colored than the reference solution Y	—	Ph. EUR
Water Content	max. 0.5	%	Ph. EUR
Loss on Drying	max. 0.5	%	USP/NF
Calcium Content	max. 200	ppm	Ph. EUR
Chloride Content	max. 100	ppm	Ph. EUR
Specific Optical Rotation	12.0 - 12.8	—	Ph. EUR / USP/NF
Limit of Oxalate	No Turbidity	—	USP/NF
Residue on Ignition	max. 0.05	%	Ph. EUR / USP/NF
Sulfate Content	No Turbidity	—	USP/NF
Arsenic Content	max. 1	ppm	JP
Assay Content	99.7 - 100.5	%	USP/NF

Typical Properties

	Value	Units	Test Method / Conditions
Bulk Density	0.80 - 1.1	g/ml	Ph. EUR
Particle Size	600 - 800	µm	Ph. EUR
A Solution Strongly Acidic	Strongly Acidic	—	Ph. EUR
B Reactions of Tartrates	Positive	—	Ph. EUR / USP/NF

Microbiological Values

	Value	Units	Test Method / Conditions
Total Aerobic Microbial Count	max. 1000	CFU/g	Ph. EUR/ USP/NF/JP
Total Yeast and Mold Count	max. 100	CFU/g	Ph. EUR/ USP/NF/JP
Escherichia Coli (in 1 g Sample)	Absent	—	Ph. EUR/ USP/NF/JP

C Infrared Absorption

IR-spectrum (ATR) equivalent reference standard

Regulatory & Compliance

Certifications & Compliance

European Pharmacopeia (Ph. Eur.),

Japan Pharmacopeia (JP),

National Formulary (NF),

REACH (Europe),

United States Pharmacopeia (USP)

Grade

Pharma Grade