KLEPTOSE® HPB Oral Grade Hydroxypropyl Betadex - Pharma

1 of 15 products in this brand

KLEPTOSE® HPB ORAL GRADE is a solubilizer and stabilizer for pharmaceutical and nutraceutical oral dosage applications.

Applications

  • Swallowable, chewable and effervescent tablets
  • Lozenges
  • Hard and soft capsules
  • Orally dissolving films
  • Blends
  • Granules
  • Pellets premix
  • Medicated confectionary
  • Syrups
  • Suspensions
  • Liquids
  • Cream
  • Paste
  • Semi-solids

Benefits

  • Improves the solubility of poorly soluble compounds
  • Can be used for taste masking of bitter or unpleasant active ingredients

Chemical Name: (2-Hydroxypropyl)-β-cyclodextrin

CAS Number: 128446-35-5

Functions: Solubilizer, Stabilizer, Taste Masker

Dosage Form: Capsules, Creams, Films, Granules, Injectables, Orally Disintegrating Tablets (ODTs), Powder & Powder Blends, Suspension, Syrups, Tablets

Labeling Claims: Acrylamide-free, BSE-free, Halal, Kosher, Non-GMO, TSE-free, Vegan

Synonyms: 2-Hydroxypropyl-Beta-Cyclodextrin, beta-Cyclodextrin 2-Hydroxypropyl Ethers, HPBCD, HPbetaCD, HPCD, Hydroxypropyl Betadex, Hydroxypropyl-Beta-Cyclodextrin

Knowde Enhanced TDS

Identification & Functionality

Chemical Family
Pharma & Nutraceuticals Functions
CAS No.
128446-35-5
EC No.
603-269-8

Features & Benefits

Applications & Uses

Properties

Physical Form
Appearance
White or almost white amorphous or crystalline powder
Typical Properties
ValueUnitsTest Method / Conditions
Conductivitymax. 200micros/cmEP / NF
Loss on Dryingmax. 10.0%EP / NF
Molar Substitution0.40 - 1.50EP / NF
Particle Size (Residue on 315 micron)min. 50%Sieve
Particle Size (Residue on 315 micron)max. 20%Sieve
Propylene Oxide (Monitoring Plan)max. 0.0001%NF
Physico-Chemical Properties
ValueUnitsTest Method / Conditions
Molar Substitution0.62EP / NF
Microbiological Values
ValueUnitsTest Method / Conditions
Escherichia coliNot detetcedper 10gEP
SalmonellaNot detectedper 10gEP
Total Aerobic Microbial Countmax. 1000CFU/gEP / NF
Total Yeasts and Moulds Countmax. 100CFU/gEP / NF

Regulatory & Compliance

Chemical Inventories
Conformity

Conforms to the requirements of the current monograph 

  • European Pharmacopeia (EP) HYDROXYPROPYLBETADEX (1804) 
  • National Formulary from USP-NF HYDROXYPROPYL BETADEX

Technical Details & Test Data

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Packaging & Availability

Packaging Information
  • ROQ Product Code: 346112
  • Article (SKU) Code: 346112102
  • Package Size & Type: 2 kg HDPE bottle

Storage & Handling

Shelf Life
5 Years
Storage and Handling

The product durability may vary according to packaging type and manufacturing plant. Proper information is shown on labeling and CoA. - We recommend to preserve the product in its unopened original packaging, preferably protected from wide variations of temperature and humidity. - Upon opening, use the product as quickly as possible to prevent moisture regain.