Roquette
KLEPTOSE® HPB Parenteral Grade Hydroxypropyl Betadex
Brand: KLEPTOSE
Applications: Parenteral
Product Families: Modified & Controlled Release, Solvents & Solubilizers, Emulsifiers & Stabilizers
Chemical Family: Cyclodextrins
KLEPTOSE® HPB Hydroxypropyl beta-cyclodextrin parenteral grade materials that are used as encapsulating agents for Rx injectables. These are modified beta-cyclodextrins for parenteral use. Modified beta-cyclodextrins used in parenteral preparations provide active substance stabilization improvement against light and oxidation as well as enhancement of solubilization of active pharmaceutical ingredients. Molecular encapsulation with modified beta-cyclodextrins has become an accepted and useful tool for pharmaceutical developers. There are currently several pharmaceutical products containing modified cyclodextrin complexes on the market. Roquette has pioneered the industrial development of cyclodextrins with its KLEPTOSE® range of beta-cyclodextrins. Hydroxypropyl betacyclodextrin (HPBCD) is a white, amorphous powder. The HPBCD molecule is a torus shaped ring with a polar hydrophilic outside and an apolar hydrophobic cavity.
Roquette
PEARLITOL® 200 SD Mannitol - Pharma
Brand: PEARLITOL
Applications: Oral
Product Families: Binders & Disintegrants, Fillers & Diluents
PEARLITOL® Mannitol pharma range is used as a filler and filler/binder as well as a bulk sweetener. The PEARLITOL® range offers a unique blend of exceptional physical and chemical stability and no hygroscopicity. Using different texturizing technologies we have designed a crystalline range of directly compressible PEARLITOL® (SD, DC and C) with various particle size allowing you to find the right product. With great organoleptic, non-cariogenic and sugar-free properties PEARLITOL® is suitable to be used in formulation addressing all type of patient population including pediatric and diabetic. PEARLITOL® can be used in in various oral dosage forms in both pharmaceutical and nutraceutical applications including swallowable tablets, orally dispersible tablets, chewable tablets, effervescent tablets, lozenges, blends, granules, pellets premix and medicated confectionary.
Roquette
PEARLITOL® 100 SD Mannitol - Pharma
Brand: PEARLITOL
Applications: Oral
Product Families: Binders & Disintegrants, Fillers & Diluents
PEARLITOL® Mannitol pharma range is used as a filler and filler/binder as well as a bulk sweetener. The PEARLITOL® range offers a unique blend of exceptional physical and chemical stability and no hygroscopicity. Using different texturizing technologies we have designed a crystalline range of directly compressible PEARLITOL® (SD, DC and C) with various particle size allowing you to find the right product. With great organoleptic, non-cariogenic and sugar-free properties PEARLITOL® is suitable to be used in formulation addressing all type of patient population including pediatric and diabetic. PEARLITOL® can be used in in various oral dosage forms in both pharmaceutical and nutraceutical applications including swallowable tablets, orally dispersible tablets, chewable tablets, effervescent tablets, lozenges, blends, granules, pellets premix and medicated confectionary.
Roquette
Roquette Dextrose Anhydrous Biopharma
Applications: Other Pharmaceutical Manufacturing Applications
Product Families: Cell Culture Solutions
Dextrose Anhydrous BioPharma from Roquette is used upstream in the cell culture process as an energy and carbon source during the production of therapeutic proteins. Roquette's in-process quality controls ensure a consistent supply of raw materials and excipients to help bring your biologics to life. Through our integrated supply chain and rigorous quality systems, we reduce the risks associated in biopharmaceutical manufacturing. Dextrose Anhydrous BioPharma is a multi-compendial material - USP, EP, JP. We are ready to help you with your upstream application needs for cell culture ingredients.
Roquette
SOLUTAB® A Croscarmellose Sodium - Pharma
Brand: SOLUTAB
Applications: Oral
Product Families: Binders & Disintegrants
SOLUTAB® Croscarmellose sodium is a superdisintegrant that provides an efficient disintegration at low level of use. Disintegration performance is obtained through the wicking and swelling capacity of SOLUTAB® that can be maximized via the selection of its origin (wood or cotton). Three grades are available to help you optimize your product selection. It is flexible as it is adapted to wet and dry granulation or direct compression processes. SOLUTAB® is a crosslinked carboxymethyl cellulose sodium. SOLUTAB® can be used in various oral dosage forms in both pharmaceutical and nutraceutical applications as an excipient including swallowable tablets, orally dispersible tablets, hard capsules, blends, granules and pellets premix.
Roquette
LYCATAB® C Partially Pregalatinized Starch - Pharma
Brand: LYCATAB
Applications: Oral
Product Families: Binders & Disintegrants, Fillers & Diluents
LYCATAB® C partially pregelatinized starch is used as a filler for gelatin capsules and filler/binder for direct compression. LYCATAB® C combines the disintegration power of starch granules with the high cohesion and good compressibility of pregelatinized starch. Native starch is a common excipient for tablet and capsule manufacture. Due to its limited flow properties, native starch often requires the use of additional excipients and production steps such as granulation. A simple physical modification of starch (a partial pregelatinization) helps overcome these difficulties and results in a multifunctional excipient. LYCATAB® C is used in oral dosage forms in both pharmaceutical and nutraceutical applications, mainly for swallowable tablets and hard capsules. It is used as a filler/binder/disintegrant.
Roquette
XYLISORB XTAB® 240 Xylitol - Pharma
Brand: XYLISORB XTAB
Applications: Oral
Product Families: Flavors & Taste Maskers, Binders & Disintegrants, Fillers & Diluents
XYLISORB® Xylitol powders can be used to provide excipient benefits including coatings, filler and filler/binder while providing nutrient benefits as a bulk sweetener. These benefits can be seen in various oral dosage forms in both pharmaceutical and nutraceutical applications including swallowable tablets and medicated confectionaries. Xylitol is a five-carbon polyol with a characteristic crystalline shape. XYLISORB® is particularly useful as a low calorie sugar-free ingredient that is known for its high natural sweetness. This makes it suitable to be used in formulation addressing all type of patient populations including pediatric and diabetic.
Roquette
PEARLITOL® 300 DC Mannitol - Pharma
Brand: PEARLITOL
Applications: Oral
Product Families: Binders & Disintegrants, Fillers & Diluents
PEARLITOL® Mannitol pharma range is used as a filler and filler/binder as well as a bulk sweetener. The PEARLITOL® range offers a unique blend of exceptional physical and chemical stability and no hygroscopicity. Using different texturizing technologies we have designed a crystalline range of directly compressible PEARLITOL® (SD, DC and C) with various particle size allowing you to find the right product. With great organoleptic, non-cariogenic and sugar-free properties PEARLITOL® is suitable to be used in formulation addressing all type of patient population including pediatric and diabetic. PEARLITOL® can be used in in various oral dosage forms in both pharmaceutical and nutraceutical applications including swallowable tablets, orally dispersible tablets, chewable tablets, effervescent tablets, lozenges, blends, granules, pellets premix and medicated confectionary.
Roquette
MICROCEL® MC-102 Microcrystalline Cellulose - Pharma
Brand: MICROCEL
Applications: Oral
Product Families: Binders & Disintegrants, Fillers & Diluents
MICROCEL® Microcrystalline cellulose is used as a filler/binder as well as a fiber source in various oral dosage forms in both pharmaceutical and nutraceutical applications. Microcrystalline cellulose has a long history of use in pharmaceutical dosage form and has had a significant role in the development of direct compression. Roquette offers a large range of MICROCEL® in order to meet different formulation, process and dosage form requirements. In addition to its nutrient and excipient properties, MICROCEL® has a large surface area allowing adsorption of particles or liquids and a certain capacity to act as a disintegrant. SD products are spray dried and offered from EXCiPACT (International Pharmaceutical Excipients Certification) certified plant. MICROCEL® can be used in swallowable tablets, hard capsules, blends, granules and pellets premix.
Roquette
PEARLITOL® 50 C Mannitol - Pharma
Brand: PEARLITOL
Applications: Oral
Product Families: Flavors & Taste Maskers, Binders & Disintegrants, Fillers & Diluents
PEARLITOL® Mannitol pharma range is used as a filler and filler/binder as well as a bulk sweetener. The PEARLITOL® range offers a unique blend of exceptional physical and chemical stability and no hygroscopicity. Using different texturizing technologies we have designed a crystalline range of directly compressible PEARLITOL® (SD, DC and C) with various particle size allowing you to find the right product. With great organoleptic, non-cariogenic and sugar-free properties PEARLITOL® is suitable to be used in formulation addressing all type of patient population including pediatric and diabetic. PEARLITOL® can be used in in various oral dosage forms in both pharmaceutical and nutraceutical applications including swallowable tablets, orally dispersible tablets, chewable tablets, effervescent tablets, lozenges, blends, granules, pellets premix and medicated confectionary.
Roquette
NEOSORB® XTAB P200 SD Sorbitol Powder - Pharma
Brand: NEOSORB® XTAB
Applications: Oral
Product Families: Flavors & Taste Maskers, Binders & Disintegrants, Fillers & Diluents
NEOSORB® Sorbitol pharma provides key functional properties of a filler and filler/binder as well as a bulk sweetener. Our sorbitol range has excellent tableting properties, as well as being non-cariogenic, non-acidogenic and sugar-free. These properties make it suitable to be used in formulation addressing all type of patient population including pediatric, diabetic. It can be used in pharmaceutical and nutraceutical formulations, in different types of powder blends, premixes, granules, pellets, swallowable tablets, chewable tablets, effervescent tablets and medicated confectionary. In coating/film forming applications it is a plasticizing agent well adapted to starches.
Roquette
LYCATAB® PGS Pregelatinized Starch - Pharma
Brand: LYCATAB
Applications: Oral
Product Families: Binders & Disintegrants, Fillers & Diluents
LYCATAB® PGS is a natural pregelatinized maize starch that has been specially developed as a binder for wet granulation. This excipient is dispersible and partially soluble in cold water and ready for use. The properties of LYCATAB® PGS result from a combination of the natural binding properties of pregels starches and a controlled manufacturing process. The latter ensure this natural origin excipient of high stability reproducible binding properties during granulation and dissolution profile of actives in the final forms. LYCATAB® PGS can be used in granules and swallowable forms in both pharmaceutical and nutraceutical applications.
Roquette
Roquette 400L-NF Corn Starch - Pharma
Applications: Oral
Product Families: Binders & Disintegrants, Fillers & Diluents
Oxidized maize starch is well known as a disintegrant filler and binder (once cooked) in nutraceutical and pharmaceutical dosage forms. It is used in a variety of dosage forms including swallowable tablets, hard capsules, blends, granules and pellets premix.
Roquette
MICROCEL® MC-101 Microcrystalline Cellulose - Pharma
Brand: MICROCEL
Applications: Oral
Product Families: Binders & Disintegrants, Fillers & Diluents
MICROCEL® Microcrystalline cellulose is used as a filler/binder as well as a fiber source in various oral dosage forms in both pharmaceutical and nutraceutical applications. Microcrystalline cellulose has a long history of use in pharmaceutical dosage form and has had a significant role in the development of direct compression. Roquette offers a large range of MICROCEL® in order to meet different formulation, process and dosage form requirements. In addition to its nutrient and excipient properties, MICROCEL® has a large surface area allowing adsorption of particles or liquids and a certain capacity to act as a disintegrant. SD products are spray dried and offered from EXCiPACT (International Pharmaceutical Excipients Certification) certified plant. MICROCEL™ can be used in swallowable tablets, hard capsules, blends, granules and pellets premix.
Roquette
NEOSORB® XTAB P300 SD Sorbitol - Pharma
Brand: NEOSORB® XTAB
Applications: Oral
Product Families: Flavors & Taste Maskers, Formulation & Processing Aids
NEOSORB® XTAB 300S is a directly compressible sorbitol powder for very hard sugar-free tablets with high flavor load. NEOSORB® XTAB sorbitol delivers a smooth, hard and uniform colored surface as well as a clean, cooling effect. Dental plaque, a sticky bacterial film that develops on dental enamel, reoccurs after every meal. Those microorganisms feed on sugar fermentation, produced by destructive acids attacking tooth enamel. NEOSORB® XTAB directly compressible polyol do not produce acids nor cause tooth decay as the oral bacteria do not metabolize them. Additionally, European regulation recognizes the nutritional benefits of polyols (Maintenance of Tooth Mineralization, Toothfriendly generic EU claims).
Roquette
NEOSORB® P 300 C Sorbitol - Pharma
Brand: NEOSORB® P
Applications: Oral
Product Families: Binders & Disintegrants, Fillers & Diluents
NEOSORB® Sorbitol pharma provides key functional properties of a filler and filler/binder as well as a bulk sweetener. Our sorbitol range has excellent tableting properties, as well as being non-cariogenic, non-acidogenic and sugar-free. These properties make it suitable to be used in formulation addressing all type of patient population including pediatric, diabetic. It can be used in pharmaceutical and nutraceutical formulations, in different types of powder blends, premixes, granules, pellets, swallowable tablets, chewable tablets, effervescent tablets and medicated confectionary. In coating/film forming applications it is a plasticizing agent well adapted to starches.
Roquette
GLYCOLYS® Low Solvent Sodium Starch Glycolate - Pharma
Brand: GLYCOLYS
Applications: Oral
Product Families: Binders & Disintegrants
GLYCOLYS® Sodium starch glycolate provides pharmaceutical and nutraceutical manufacturers with a range of superdisintegrants for different formulation needs. Our GLYCOLYS® product provides this benefit for swallowable tablets, orally dispersible tablets and hard capsules. Roquette has been producing sodium starch glycolate for more than 20 years. We have developed different grades of GLYCOLYS® to meet specific needs, such as withstanding high shear granulation, acidic conditions or with a low organic solvent content.
Roquette
XYLISORB® 300 Xylitol - Pharma
Brand: XYLISORB
Applications: Oral
Product Families: Binders & Disintegrants, Pharmaceutical Coatings, Flavors & Taste Maskers
XYLISORB® Xylitol powders can be used to provide excipient benefits including coatings, filler and filler/binder while providing nutrient benefits as a bulk sweetener. These benefits can be seen in various oral dosage forms in both pharmaceutical and nutraceutical applications including swallowable tablets and medicated confectionaries. Xylitol is a five-carbon polyol with a characteristic crystalline shape. XYLISORB® is particularly useful as a low calorie sugar-free ingredient that is known for its high natural sweetness. This makes it suitable to be used in formulation addressing all type of patient populations including pediatric and diabetic.
Roquette
LYCADEX® PF Dextrose Monohydrate Pyrogen Free
Brand: LYCADEX
Applications: Parenteral, Dialysis
Product Families: Formulation & Processing Aids, Active Pharmaceutical Ingredients (APIs)
LYCADEX® PF is a dextrose monohydrate pyrogen-free that is a physiological sugar used to provide excipient and API benefits. As an excipient it is an isotonic agent and as an API it can be used as carbohydrate source, and an Osmotic Agent . These benefits are possible in injectable applications including large volume parenteral, total parenteral nutrition and Rx excipients. In Dialysis it can be used as osmotic agent for hemodialysis and peritoneal dialysis. With LYCADEX® PF, Roquette has pioneered the development of this level of quality in a pyrogen-free dextrose monohydrate product that has set a standard recognized around the world.
Roquette
PEARLITOL® PF Mannitol Pyrogen Free - Pharma
Brand: PEARLITOL
Applications: Oral, Parenteral
Product Families: Formulation & Processing Aids, Carriers & Bulking Agents, Active Pharmaceutical Ingredients (APIs)
Chemical Family: Sugars, Sugar Alcohols
PEARLITOL® PF, a mannitol pyrogen-free from Roquette, is used for parenteral preparations and Rx injectables. As an API it serves as an osmotic diuretic agent in small and large volume parenteral injectables. As an excipient it is used for Rx injectables as an isotonic agent and a bulking agent for freeze dried powder for injection or infusion. Mannitol pyrogen free is also used to reduce elevated pressure in the brain (cerebral oedema) and in the eyes. In these critical solutions, mannitol acts as a pharmaceutical active ingredient and its production has to comply with the internationally accepted GMP standards. Due to its physical and chemical properties mannitol is the choice excipient for freeze-dried powder for injection or infusion.
Roquette
XYLISORB XTAB® 400 Xylitol - Pharma
Brand: XYLISORB XTAB
Applications: Oral, Excipients & Coatings, Nutraceuticals & Supplements
Product Families: Flavors & Taste Maskers, Fillers & Diluents, Binders & Disintegrants
Chemical Family: Sugars, Sugar Alcohols
XYLISORB® Xylitol powders can be used to provide excipient benefits including coatings, filler and filler/binder while providing nutrient benefits as a bulk sweetener. These benefits can be seen in various oral dosage forms in both pharmaceutical and nutraceutical applications including swallowable tablets and medicated confectionaries. Xylitol is a five-carbon polyol with a characteristic crystalline shape. XYLISORB® is particularly useful as a low calorie sugar-free ingredient that is known for its high natural sweetness. This makes it suitable to be used in formulation addressing all type of patient populations including pediatric and diabetic.
Roquette
KLEPTOSE® HPB Oral Grade Hydroxyprpyl Betadex - Pharma
Brand: KLEPTOSE
Applications: Parenteral, Topical, Oral
Product Families: Solvents & Solubilizers, Emulsifiers & Stabilizers, Flavors & Taste Maskers
Chemical Family: Cyclodextrins
KLEPTOSE® HPB ORAL GRADE can be used to provide excipient benefits in many oral dosage applications. Hydroxypropyl beta-cyclodextrin can improve the solubility of poorly soluble compounds and can be used for taste masking of bitter or unpleasant active ingredients. It can also act as a stabilizer in these applications. Roquette has pioneered the industrial development of cyclodextrins with its KLEPTOSE® range of hydroxypropyl beta-cyclodextrins. These products are used in various oral dosage forms in both pharmaceutical and nutraceutical applications including swallowable tablets, chewable tablets, effervescent tablets, lozenges, hard capsules, soft capsules, orally dissolving films, blends, granules, pellets premix, medicated confectionary, syrups, suspensions, liquids, cream, paste and semi-solids.
Roquette
KLEPTOSE® Linecaps 17 Pea Maltodextrin - Pharma
Brand: KLEPTOSE
Applications: Topical, Excipients & Coatings, Oral
Product Families: Solvents & Solubilizers, Modified & Controlled Release, Flavors & Taste Maskers
Chemical Family: Carbohydrates
KLEPTOSE® LINECAPS Pea Maltodextrin can provide various benefits to pharma oral dosage and nutraceutical forms including acting as a solubilizer, stabilizer and taste-making agent. It can be used in swallowable tablets; chewable tablets; effervescent tablets; losenges; hard capsules; soft capsules; coatings; orally dissolving films; blends, granules, pellets premix; medicated confectionary; syrups, suspensions and liquids; and creams, paste and semi-solids.
Roquette
Roquette Dextrose Anhydrous C - Pharma
Applications: Oral, Nutraceuticals & Supplements
Product Families: Other Nutraceutical Ingredients, Fillers & Diluents, Binders & Disintegrants
Chemical Family: Carbohydrates
Dextrose Anhydrous provides key excipient and nutrient benefits as a filler and a carbohydrate source. This product has a natural low water content compared to dextrose monohydrate thereby provide superior stability. It is a sugar carbohydrate used for pharma oral dosage and nutraceutical forms. Glucose or dextrose is the monomer of natural starch polymer. This monomer is also the natural physiological sugar in the human body. Dextrose anhydrous is available as a range of products to meet the diverse requirements of manufacturers. Dextrose anhydrous can provide benefit to swallowable tablets, chewable tablets, effervescent tablets and medicated confectionaries. As an excipient it can be used as a filler. As a nutrient it is a carbohydrate source.
Roquette
PEARLITOL® Flash Mannitol - Pharma
Brand: PEARLITOL
Applications: Oral, Nutraceuticals & Supplements
Product Families: Fillers & Diluents, Binders & Disintegrants
Chemical Family: Sugars, Sugar Alcohols
PEARLITOL® Flash provides excipient functional properties of filler/binder as well as some disintegrant benefit to your orally dispersable tablets. PEARLITOL® Flash offers excellent chemical inertness, consistent rapid disintegration whatever the compression force making tablet formulation surprisingly simple. It is a compound of mannitol and starch adapted to direct compression formulation.PEARLITOL® Flash can be used in nutraceutical and pharma oral dosage forms including fast disintegrating tablets and orally dispersible tablets.
Roquette
PEARLITOL® 25 C Mannitol - Pharma
Brand: PEARLITOL
Applications: Oral, Nutraceuticals & Supplements
Product Families: Flavors & Taste Maskers, Fillers & Diluents, Binders & Disintegrants
Chemical Family: Sugars, Sugar Alcohols
PEARLITOL® 25 C Mannitol is dedicated to nutraceutical and pharmaceutical oral dosage applications needing the benefit of a filler as well as a bulk sweetener. It is a sugar-free and non-cariogenic excipient with very high physical and chemical stability and no hygroscopicity.
Roquette
KLEPTOSE® HPB Biopharma Hydroxypropyl Betadex
Brand: KLEPTOSE
Applications: Parenteral
Product Families: Modified & Controlled Release, Emulsifiers & Stabilizers
Chemical Family: Cyclodextrins
Roquette offers two hydroxypropyl betacyclodextrin, low endotoxin grade materials that provide protein stabilization for your biopharmaceutical downstream applications. These are cyclic oligosaccharides with a bucket-like structure. With a hydrophobic internal cavity and hydrophilic exterior, these starch derivatives can encapsulate molecules, forming inclusion complexes where lipophilic compounds are non-covalently bound within the cavity.Their unique function to encapsulate and shield water insoluble materials can be utilized to shield exposed hydrophobic residues on aggregation-prone proteins, thereby modulating protein aggregation. Widely used in the formulation of small molecules, highly soluble betacyclodextrin derivatives like our KLEPTOSE® HP BioPharma and KLEPTOSE® HPB BioPharma show promise as a multifunctional excipient suitable for biopharma applications.Representing a promising class of excipients that can reduce protein aggregation induced by physical stress, cyclodextrins can serve as an alternative option to currently used excipients, or a tool to synergistically complement your biotherapeutic formulations. These materials are suitable for use in biopharmaceutical manufacturing and as an excipient for injectable dosage forms. Contact us today at Roquette to talk to us about these multicompendial materials - EP, USP and JP.
Roquette
Roquette POWDERED NF CORN STARCH
Applications: Oral, Nutraceuticals & Supplements
Product Families: Fillers & Diluents, Binders & Disintegrants
Chemical Family: Non-Ionics
Native starches are well known as disintegrants, fillers and binders (once cooked) in both pharmaceutical and nutraceutical applications. They are used in a variety of dosage forms including swallowable tablets, hard capsules, blends, granules and pellets premix. Roquette provides native starches of different plant origins: maize, wheat and potato. They also provide more specific grades like extra white maize starch, overdried starches, pea starch and potato starch.
