Products

KLEPTOSE® HPB Hydroxypropyl Betadex Cyclodextrin is a modified beta-cyclodextrin parenteral grade material that can be used as an encapsulating agent for Rx injectables. Benefits Improves stabilization of active substances against light and oxidation Enhances solubilization of active pharmaceutical ingredients Features White, amorphous powder Molecule is a torus-shaped ring with a polar hydrophilic outside and an apolar hydrophobic cavity

PEARLITOL® Mannitol is used in pharmaceutical and nutraceutical formulations as a filler, filler/binder and bulk sweetener in various oral dosage applications. Applications Swallowable, orally dispersible, chewable and effervescent tablets Lozenges Blends Granules Pellets premix Medicated confectionery Features Unique blend of exceptional physical and chemical stability and no hygroscopicity Directly compressible crystalline range with various particle sizes Great organoleptic, non-cariogenic and sugar-free properties Suitable for use in formulations addressing pediatric and diabetic patient populations

PEARLITOL® Mannitol pharma range is used in pharmaceutical and nutraceutical formulations as a filler, filler/binder and bulk sweetener in oral dosage form applications. Applications Swallowable, orally dispersible, chewable and effervescent tablets Lozenges Blends Granules Pellets premix Medicated confectionery Features Unique blend of exceptional physical and chemical stability and no hygroscopicity Directly compressible crystalline range with various particle sizes Great organoleptic, non-cariogenic and sugar-free properties Suitable for use in formulations addressing pediatric and diabetic patient populations

SOLUTAB® Croscarmellose sodium is used in pharmaceutical and nutraceutical applications as a superdisintegrant for various oral dosage forms. Applications Swallowable tablets Orally dispersible tablets Hard capsules Blends Granules Pellets premix Benefit Efficient disintegration at low use level Features Crosslinked carboxymethyl cellulose sodium Three grades are available Disintegration performance is obtained through the wicking and swelling capacity that can be maximized via the selection of its origin (wood or cotton) Can be adapted to wet and dry granulation or direct compression processes

LYCATAB® C partially pregelatinized starch is used in pharmaceutical and nutraceutical applications as a multifunctional for oral dosage forms. Applications gelatin capsules as a filler direct compression applications as a filler/binder swallowable tablets and hard capsules as a filler/binder/disintegrant Features Combines the disintegration power of starch granules with the high cohesion and good compressibility of pregelatinized starch Due to limited flow properties, often requires the use of additional excipients and production steps such as granulation or partial pregelatinization

XYLISORB® Xylitol powders can be used as a low calorie, sugar-free ingredient that provides high natural sweetness. A five-carbon polyol with a characteristic crystalline shape, it provides excipient benefits as a coating, filler and filler/binder and nutrient benefits as a bulk sweetener. It can be used: in pharmaceutical and nutraceutical oral dosage applications, including swallowable tablets and medicated confectioneries in formulations addressing all types of patient populations, including pediatric and diabetic

PEARLITOL® Mannitol pharma range is used in pharmaceutical and nutraceutical formulations as a filler, filler/binder and bulk sweetener in various oral dosage applications. Applications Swallowable, orally dispersible, chewable and effervescent tablets Lozenges Blends Granules Pellets premix Medicated confectionery Features Unique blend of exceptional physical and chemical stability and no hygroscopicity Directly compressible crystalline range with various particle sizes Great organoleptic, non-cariogenic and sugar-free properties Suitable for use in formulations addressing pediatric and diabetic patient populations

Maize Starch 5% native acts as a thickener, humectant and bulking agent for cakes, pastries, custards, fillings, sauces and other food applications. Benefits Shelf-life extension Texturizing Water retention

MICROCEL® Microcrystalline cellulose is used in pharmaceutical and nutraceutical applications as a filler/binder and fiber source in various oral dosage forms. Applications Swallowable tablets Hard capsules Blends Granules Pellets premix Features Available in a large range to meet different formulation, process and dosage form requirements Large surface area allows adsorption of particles or liquids and a certain capacity to act as a disintegrant Spray dried and offered from EXCiPACT (International Pharmaceutical Excipients Certification) certified plant

PEARLITOL® Mannitol pharma range is used in pharmaceutical and nutraceutical applications as a filler, filler/binder and bulk sweetener for various oral dosage forms. Applications Swallowable, orally dispersible, chewable and effervescent tablets, Lozenges Blends Granules Pellets premix Medicated confectionery Benefit Suitable for use in formulations addressing all types of patient populations, including pediatric and diabetic Features Directly compressible Unique blend of exceptional physical and chemical stability No hygroscopicity Organoleptic, non-cariogenic and sugar-free properties

LYCATAB® PGS is used in pharmaceutical and nutraceutical applications as a binder for wet granulation. Features Natural pregelatinized maize starch resulting from a combination of the natural binding properties of pregels starches and a controlled manufacturing process Dispersible and partially soluble in cold water and ready for use High-stability reproducible binding properties during granulation and dissolution profile of actives in final forms Can be used in granules and swallowable forms

NEOSORB® Sorbitol pharma is used in pharmaceutical and nutraceutical formulations as a filler, filler/binder and bulk sweetener for oral dose applications. It can also be used as a plasticizing agent well-adapted to starches in coating/film forming applications. Applications Powder blends Premixes Granules Pellets Swallowable, chewableand effervescent tablets Medicated confectionary Features Excellent tableting properties Non-cariogenic Non-acidogenic Sugar-free Suitable for use in formulations addressing pediatric and diabetic patient populations

Roquette 400L-NF Corn Starch is an oxidized maize starch that can be used as a disintegrant filler and binder (once cooked) in a variety of nutraceutical and pharmaceutical dosage forms, including swallowable tablets, hard capsules, blends, granules and pellets premix. Benefits Acrylamide-free BSE-free Halal and Kosher certified Melamine-free TSE-free Vegan

MICROCEL® Microcrystalline cellulose is used in both pharmaceutical and nutraceutical applications as a filler/binder and fiber source in various oral dosage forms. Applications Swallowable tablets Hard capsules Blends Granules Pellets premix Features Available in a large range to meet different formulation, process and dosage form requirements Large surface area allows adsorption of particles or liquids and a certain capacity to act as a disintegrant Spin flash-dried

Tooth-friendly NEOSORB® XTAB 300S is a directly compressible sorbitol powder for very hard sugar-free tablets with high flavor load. Benefits Delivers a smooth, hard and uniform colored surface. Provides a clean, cooling effect. Does not produce acids or cause dental plaque or tooth decay. Nutritional benefits (maintenance of tooth mineralization, tooth-friendly generic EU claims) recognized by European regulations.

NEOSORB® Sorbitol pharma is used in pharmaceutical and nutraceutical formulations as a filler, filler/binder and bulk sweetener in various oral dosage applications, and as a plasticizing agent well-adapted to starches in coating/film forming applications. Applications Swallowable, orally dispersible, chewable and effervescent tablets Lozenges Blends Granules Pellets premix Medicated confectionery Features Excellent tableting properties Great organoleptic, non-cariogenic and sugar-free properties Suitable for use in formulations addressing pediatric and diabetic patient populations

GLYCOLYS® Low Solvent Sodium Starch Glycolate is a superdisintegrant for pharmaceutical and nutraceutical swallowable tablets, orally dispersible tablets and hard capsules. Features Different grades designed to meet specific needs: Withstanding high shear granulation Acidic conditions Low organic solvent content

XYLISORB® Xylitol powders can be used in pharmaceutical and nutraceutical applications as a filler, filler/binder and bulk sweetener that provides nutrient benefits. Applications Swallowable tablets Medicated confectionaries Features Five-carbon polyol with a characteristic crystalline shape Low calorie sugar-free ingredient with high natural sweetness Suitable for use in formulations addressing pediatric and diabetic patient populations

NEOSORB® XTAB 300S is a directly compressible sorbitol powder that can be used for very hard, sugar-free tablets with high flavor load. Benefits Delivers a smooth, hard and uniform colored surface Provides a clean, cooling effect Does not produce acids or cause dental plaque or tooth decay Nutritional benefits (maintenance of tooth mineralization, tooth-friendly generic EU claims) recognized by European regulations Features Non-cariogenic Sugar-free

XYLISORB® Xylitol powders are used in coatings for pharmaceutical and nutraceutical formulations, and as a filler, filler/binder and bulk sweetener that provides nutrient benefits. Applications Swallowable tablets Medicated confectionery Features Five-carbon polyol with a characteristic crystalline shape Low-calorie, sugar-free ingredient with high natural sweetness Suitable for use in formulations addressing pediatric and diabetic patient populations

LYCASIN® Maltitol liquids are used as vehicle and humectant for syrups, suspensions and as sweetener in lozenges and medicated confectionary. LYCASIN® has taste and sweetness properties ideal for the preparation of sugar-free syrups made for pediatric and diabetic population.

PEARLITOL® 25 C Mannitol is a filler and bulk sweetener that can be used for pharmaceutical oral dosage applications. Benefits BSE-free Halal and Kosher certified Melamine-free Non-carcinogenic Non-hazardous Sugar-free TSE-free Vegan Features High physical and chemical stability Cooling effect Non-cariogenic Low hygroscopicity

PEARLITOL® CR-H - HYPROMELLOSE – MANNITOL is a combination of hypromellose (HPMC) and mannitol that offers excipient functional properties for tablet formulations. It serves as a binder while also providing controlled release characteristics. Specifically designed for direct compression formulations, Pearlitol® CR-H is suitable for use in oral tablets for both pharmaceutical and nutraceutical applications that require controlled properties.

PEARLITOL® Flash is used in nutraceutical and pharma oral dosage forms as a filler/binder for orally dispersable tablets. Applications Fast disintegrating tablets Orally dispersible tablets Benefits Excipient functional properties Disintegrant benefit Simplifies tablet formulation Features Compound of mannitol and starch adapted to direct compression formulation Excellent chemical inertness Consistent rapid disintegration under any compression force

KLEPTOSE® HPB Biopharma Hydroxypropyl Betadex Cyclodextrin is a low endotoxin grade materials that provides protein stabilization for biopharmaceutical downstream applications. With a hydrophobic internal cavity and hydrophilic exterior, KLEPTOSE® HPB BioPharma can encapsulate molecules, forming inclusion complexes where lipophilic compounds are non-covalently bound within the cavity. It is suitable for use in biopharmaceutical manufacturing and as an excipient for injectable dosage forms. Benefits Unique ability to encapsulate and shield water insoluble materials can be utilized to shield exposed hydrophobic residues on aggregation-prone proteins, thereby modulating protein aggregation Shows promise as a multifunctional excipient suitable for biopharma applications Can serve as a tool to synergistically complement biotherapeutic formulations Multicompendial material (EP, USP, JP) Features Starch derivative Cyclic oligosaccharide with a bucket-like structure

KLEPTOSE® LINECAPS Pea Maltodextrin Cyclodextrin can be used as a solubilizer, stabilizer and taste-making agent in pharma oral dosage applications. Applications Swallowable, chewable and effervescent tablets Lozenges Hard and soft capsules Orally dissolving films Blends Granules Pellets premix Medicated confectionery Syrups Suspensions Liquids Cream Paste Semi-solids

KLEPTOSE® HPB Oral Grade is a solubilizer and stabilizer for pharmaceutical and nutraceutical oral dosage applications. Applications Swallowable, chewable and effervescent tablets Lozenges Hard and soft capsules Orally dissolving films Blends Granules Pellets premix Medicated confectionary Syrups Suspensions Liquids Cream Paste Semi-solids Benefits Improves the solubility of poorly soluble compounds Can be used for taste masking of bitter or unpleasant active ingredients

Roquette Pea Starch N735 is a versatile ingredient that serves as an anti-caking agent, binder, carbohydrate source, and texturizing agent. Available in powder form, this neutral-scented, white to off-white powder effortlessly enhances your formulations. It offers alcohol solubility and a neutral taste.

NEOSORB® BioPharma Low endotoxin grade sorbitol provides protein stabilization in your biopharmaceutical downstream applications. Known for its high water solubility, it is a proven formulation aid for biopharmaceuticals. Sorbitol is used as an excipient in over 35 commercial mAbs, therapeutic proteins and vaccines. Roquette's in process quality controls ensure a consistent supply of raw materials and excipients to help bring your biologics to life. Through our integrated supply chain and rigorous quality systems, we reduce the risks associated in biopharmaceutical manufacturing. NEOSORB® BioPharma is suitable for use in biopharmaceutical manufacturing and as an excipient for injectable dosage forms. Contact us today to talk about our multi-compendial materials - EP, JP, and USP.

PEARLITOL® 200 GT-EXP is a direct compression excipient specifically formulated to enhance the manufacturing process of tablets. This exceptional excipient is designed to address key challenges such as capping, while improving flowability and tabletability. PEARLITOL® 200 GT-EXP is a granulated form of mannitol known for its outstanding physical and chemical stability. With its high API compatibility and non-hygroscopic nature, it ensures consistent quality and performance in pharmaceutical formulations. As a non-cariogenic and non-acidogenic sugar-free sweetener, it is suitable for various patient populations, including pediatric and diabetic individuals. PEARLITOL® 200 GT-EXP finds application in a wide range of dosage forms, including tablets (lozenges, swallowable, orally dispersible, chewable, and effervescent) as well as powder blends (sachets, oral stick packs, and hard gelatin capsules).

StarLac® Co-processed lactose starch is a filler/binder with strong disintegrant properties. The co-processing offers superior benefit compared to a blend of lactose and starch. It allows to improve the performance (hardness, friability, disintegration time) of your formulation. Specifically designed for direct compression applications, StarLac® is also an excellent filler/binder in dry granulation processes. StarLac® can be used in various oral dosage forms in pharmaceutical applications including granules, swallowable tablets, orally dispersible tablets and hard capsules.

NEOSORB® 70/02 B is a liquid sorbitol with crystalline properties. This versatile solution serves as a potent bulk sweetener for liquid dosage forms and a humectant for semi-solids. Comprising sorbitol and hydrogenated oligomers, NEOSORB® 70/02 B provides an ideal alternative to sucrose, aligning with organoleptic and health needs. It's sugar-free, low-calorie, non-cariogenic, and suitable for diabetics, making it a smart choice for your formulation needs.

PEARLITOL® PF is a pyrogen-free mannitol that is used for parenteral preparations and Rx injectables. Applications Osmotic diuretic agent in small and large volume parenteral injectables Isotonic agent and bulking agent for freeze-dried powder for Rx injection or infusion Pharmaceutical API used to reduce elevated pressure in the brain (cerebral oedema) and in the eyes (note: production has to comply with the internationally accepted GMP standards)

PEARLITOL® Mannitol pharma range is used as a filler and filler/binder. The PEARLITOL® range offers a unique blend of exceptional physical and chemical stability and no hygroscopicity. Using different texturizing technologies we have designed a crystalline range of directly compressible PEARLITOL® with various particle size allowing you to find the right product. With great organoleptic, non-cariogenic and sugar-free properties PEARLITOL® is suitable to be used in formulation addressing all type of patient population including pediatric and diabetic. PEARLITOL® can be used in in various oral dosage forms in both pharmaceutical and nutraceutical applications including swallowable tablets, orally dispersible tablets, chewable tablets, effervescent tablets, lozenges, blends, granules, pellets premix and medicated confectionary

Dextrose Anhydrous is a sugar carbohydrate used for as a filler and a carbohydrate source in pharma oral dosage and nutraceutical forms, including swallowable tablets, chewable tablets, effervescent tablets and medicated confectionaries. Features Monomer of natural starch polymer that is also the natural physiological sugar in the human body Provides key excipient and nutrient benefits Natural low water content compared to dextrose monohydrate t High stability Available as a range of products to meet application requirements of manufacturers

LYCADEX® PF is a pyrogen-free dextrose monohydrate that can be used: as isotonic agent in Rx excipients and in injectable applications including large volume parenteral, total parenteral nutrition as a carbohydrate source and osmotic agent for hemodialysis and peritoneal dialysis