Knowde Enhanced TDS
Identification & Functionality
- Chemical Family
- Chemical Name
- INCI Name
- Ingredient Origin
- Cosmetic Ingredients Functions
- CAS No.
- 36062-04-1
- EC No.
- 609-201-3
- Technologies
- Product Families
- Product Details
Product code : 2028
Category : Intended for Cosmeceutical application
Solvent used in manufacture : Acetone, Isopropyl alcohol
Molecular Formula : C21H24O6
Chemical Name : Tetrahydrodiferuloylmethane
Synonyms : 1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione
Excipient used : None
Features & Benefits
- Labeling Claims
- Product Highlights
Traditional medicinal knowledge supports the usage of turmeric as topically application to improve skin health, helps to relieve pain and inflammation. The rhizome contains many bioactive phenolic compounds known as Curcuminoids, out of which the most abundant one is Curcumin.
The colorless derivative of Curcumin is Tetrahydrocurcumin (SabiWhite®). It is a potent inhibitor of melanogenesis and its activity was found to be several fold greater than kojic acid, glabridin, other synthetic and natural extracts. It also provides antioxidant protection benefiting skin tone, texture and integrity.
Applications & Uses
- Markets
- Applications
- Skin Care Applications
- Recommended Uses & Known Application
SabiWhite® offers effective topical antioxidant protection in a holistic way. The in vitro studies revealed that SabiWhite® offers effective topical antioxidant “bioprotectant” action, efficiently helps to prevent the formation of free radicals, while quenching pre-formed ones as well. This dual action protects the skin cells from damage by UV radiation. In a randomized, double-blind, placebo-controlled study in 50 human subjects, 0.25% SabiWhite® cream was found to be effective and safe alternative to 4% hydroquinone cream in depigmenting formulation. SabiWhite® is safe for topical use with no irritant or sensitization side effects.
Properties
- Appearance
- Off white to creamy white powder
- Insoluble in
- Water
- Soluble in
- Acetone
- Chemical Properties
- Physical Properties
- Other Properties
- Microbiological Values
| Value | Units | Test Method / Conditions | |
| Tetrahydrocurcumin Content (HPLC - on dry basis) | 96.0 - 102.0 | % w/w | SLL/STP-T-006 |
| Value | Units | Test Method / Conditions | |
| Loss on Drying (Dried at 60°C, Under Vacuum) | max. 1.0 | % w/w | USP <731> |
| Loose Bulk Density | 0.30 - 0.60 | g/ml | USP <616> |
| Sieve Test (Passes Through #20 Mesh) | min. 100 | % w/w | USP <786> |
| Sieve Test (Passes Through #40 Mesh) | min. 90 | % w/w | USP <786> |
| Melting Range | 85 - 100 | °C | USP <741> |
| Sieve Test (Passes Through #80 Mesh) | min. 80 | % w/w | USP <786> |
| Residue on Ignition | max. 1.0 | % w/w | USP <281> |
| Tapped Bulk Density | 0.40 - 0.90 | g/ml | USP <616> |
| Value | Units | Test Method / Conditions | |
| Arsenic Content | max. 1 | ppm (μg/g) | USP <2232> |
| Cadmium Content | max. 1 | ppm (μg/g) | USP <2232> |
| Lead Content | max. 3 | ppm (μg/g) | USP <2232> |
| Mercury Content | max. 0.1 | ppm (μg/g) | USP <2232> |
| Value | Units | Test Method / Conditions | |
| Coliforms Count | max. 10 | cfu/g | BAM 2001, 8th Edition, Chapter 4 |
| Escherichia Coli | Negative | per 10g | USP <62> |
| Pseudomonas Aeruginosa | Negative | per 10g | USP <62> |
| Salmonella | Negative | per 10g | USP <62> |
| Staphylococcus Aureus | Negative | per 10g | USP <62> |
| Total Aerobic Microbial Count | max. 5000 | cfu/g | USP <61> |
| Total Yeasts and Molds Count | max. 100 | cfu/g | USP <61> |
Regulatory & Compliance
Packaging & Availability
- Regional Availability
Storage & Handling
- Shelf Life
- 5 Years
- Storage Condition
- Store at room temperature.