METOLOSE® SR 90SH-15000SR

1 of 32 products in this brand
METOLOSE® SR 90SH-15000SR provides a genuine consistency in Sustained release (matrix tablets). It can be used for semi solid drug products.

Chemical Name: Hydroxypropyl Methylcellulose

Functions: Binder, Controlled Release Agent, Sustained Release Agent

Dosage Form: Tablets

Labeling Claims: BSE-free, Kosher, Non-GMO, Solvent-free, TSE-free

Certifications & Compliance: DMF Type IV, European Pharmacopeia (Ph. Eur.), FDA Compliant, GMP, Generally Recognized As Safe (GRAS), JECFA (FAO/WHO), Japan Pharmacopeia (JP), Kosher, The Food Allergen Labeling & Consumer Protection Act of 2004 (FALCPA), United States Pharmacopeia (USP)

    Knowde Enhanced TDS

    Identification & Functionality

    CAS No.
    9004-65-3
    EC No.
    618-389-6
    Structure

    METOLOSE® SR 90SH-15000SR - Structure

     

    Features & Benefits

    Features
    • For Hydrophilic matrix formulation of API and METOLOSE® SR to extend the dissolution. The dosage forms can be obtained by direct compression or granulation process.
    • METOLOSE® SR has specifications of particle size which can be suitable for sustained release application.
    • Dissolution profile can be easily adjusted by selecting appropriate grade.
    • Recommendable amount of METOLOSE® SR is more than 20% in the formulation in order to form the stable gel layer.

    Applications & Uses

    Dosage Form

    Properties

    Physical Form
    Typical Properties
    ValueUnitsTest Method / Conditions
    Hydroxypropoxy Content8.5 - 10.5%
    Methoxy Content22.0 - 24.0%
    Viscosity11250 - 21000
    Particle Size Distribution
    ValueUnitsTest Method / Conditions
    Particle Size at D2020 - 40µm
    Particle Size at D5050 - 80µm
    Particle Size at D80100 - 160µm
    Note

    *Values in the table are viscosities of 2 w/w % aqueous solution at 20°C

    Regulatory & Compliance

    Packaging & Availability

    Package
    • Packaging material: Double-layered polyethylene bag in fiber drum
    • Net weight: Depending on grades

    Storage & Handling

    Storage

    Keep dry. Store away from excess heat and sunlight. Store in sealed containers.