Knowde Enhanced TDS
Identification & Functionality
- Chemical Family
- Ingredient Origin
- Cosmetic Ingredients Functions
- Technologies
Features & Benefits
- Benefit Claims
- Labeling Claims
- Product Benefits
- Clinic anti-oxidant versus placebo (after day 28)
- Clinic anti-oxidant: +15% versus D0
- Reinforces the anti-oxidant capacity of the skin versus placebo
Applications & Uses
- Markets
- Applications
- Skin Care Applications
- Use Level
- 1%
- Mode of Action
Protect the genes of Eve
- Immediate (-100% versus control) & long lasting (-36% versus control) anti-oxidant, protecting the mitochondria
- More efficient than a seaweed extract
Ephemeral sourcing for anti-aging
- Mitochondrial DNA protection: +63% aconitase
- Protects cells from free radicals: +19% catalase
Properties
- Soluble in
- Fats and oils
Regulatory & Compliance
- Certifications & Compliance
Technical Details & Test Data
- Efficacy Tests
Ephemeral cells in the lifecycle of macroalgae
EPHEMER™ is a gametophyte extract taken from macroalgae cells grown in a laboratory and harvested at an ephemeral stage in the life cycle of Undaria Pinnatifida seaweed.
EPHEMER™ – First cosmetic active ingredient from macroalgae cell culture for a long anti-aging effect.
EPHEMER™ is a gametophyte extract taken from macroalgae cells grown in a laboratory and harvested at an ephemeral stage in the life cycle of Undaria Pinnatifida seaweed. This in-vitro cultivation of a cosmetic product is entirely unique.
Vitro & vivo results show Immediate & long term anti-oxidant efficacy.
After 1 hour, the anti-oxidant efficacy on the cellular free radicals is higher (-116% versus control) than a common sporophyte seaweed extract of Undaria Pinnatifida (-71% versus control) After 1 hour, the anti-oxidant efficacy on the mitochondrial free radicals is specific (-100% versus control). The common seaweed extract (sporophyte) of Undaria Pinnatifida has no efficacy.
After 5 days, EPHEMER™ confirms its anti-oxidant efficacy on the mitochondrial free radicals (-36% versus control). EPHEMER™ boosts the energetic yield.With EPHEMER™ after 5 days, the energetic yield is 24% higher on senescent cells versus non treated senescent cells.
After 8 days, EPHEMER™ preserves mitochondrial DNA, which is essential for proper mitochondrial function. Mitochondrial DNA are also called 'Eve's Genes' since they are inherited solely from the mother. After 8 days, increase of catalase, as a detoxifying enzyme that contributes to fight against a large spectrum of free radicals. This property has been confirmed through in-vivo testing.
After 28 days, IN VIVO the skin shows a better ability to fight free radicals, a cause of skin aging, versus placebo.
Sporophyte is the common macroalgae form. Gametophytes are cells liberated by the sporophytes in the reproduction lifecycle, as an ephemeral stage. Gametophytes are the Source of Life for the survival of the species. In the ocean, gametophytes are unstable and not available in large quantities. In photobiorectors, gametophytes are stable thanks to specific conditions.
Erwan Le Gélébart, R&D Project Manager at BiotechMarine: “This is a major innovation for the world of cosmetic active ingredients. Macroalgae cells have the amazing ability to transform light and minerals into organic molecules. This launch confirms the acceleration of Marine Biotechnologies development into SEPPIC.”