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SEPPIC INC Heterosides

Producer:  SEPPIC INC
Heterosides is a highly purified water-soluble extract of Centella asiatica for skin barrier function improvement. This product provides stratum corneum formation enhancement, tight junctions reinforcement, differentiation normalization and activation of the deeper layers of the epidermis. Its anti-wrinkle effect has been recently demonstrated on the crow’s feet. Significant TEWL reduction on volunteers with a dry skin has been also observed. This is a titrated blend of the glycosylated triterpens Asiaticoside and Madecassoside. This is an active ingredient for use in intense skin care applications for dry and dehydrated skin, as well as mature skin. It comes as a crystalline powder.
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Identification & Functionality

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Features & Benefits

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Product Benefits
  • TEWL reduction: -8% vs Placebo (D28)
  • Smoothing effect:-36% vs Placebo(D28)
  • Anti-wrinkle effect: -19% vs Placebo(D56)

Applications & Uses

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Mode of Action
  • Reinforce the "mortar" (Ceramides-2: +44%)
  • Strenghten the "brick" envelop (Involucrin, Loricrin, Filaggrin)
  • Boost cell cohesion (tight junctions)
  • Moisturize (AQP3: +29%) & soothe (PGE-2, IL-8, IL-1α)
  • It prevents dehydration by reactivating all the natural mechanisms that restructure and pamper the skin barrier
  • It erases fine lines and wrinkles by enhancing water retention and dermis scaffold

Properties

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Physical Form
Soluble in
Water
Typical Properties
ValueUnitsTest Method / Conditions
Active Contentmax. 70%-

Regulatory & Compliance

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Certifications & Compliance

Packaging & Availability

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Most Viewed Documents

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Brochure
ADIPOLESS™, ADIPOSLIM™, ALARIANE®, AMBRE OCEANE® SPE, AMONYL™ 675SB, Antileukine™ 6, AQUAXYL™, BIOENERGIZER™ P BG PF, BIOEXTENDER® SPE, BIOPLASMA™ BG 40, BIOPLASMA™ FA, BIORESTORER™ PF, SEPPIC INC BLUE SEAKALE HC, BLUE SEAKALE SC™, CAPIGEL™ 98, CELTOSOME™ Crithmum Maritimum, CELTOSOME™ Eryngium Maritimum, CERAMOSIDES™ HP, Cire De Lanol CTO™, CODIAVELANE™ BG PF, CONTACTICEL™, EASYNOV™, EMOGREEN™ L15, EMOGREEN™ L19, EMOSMART™ C28, EMOSMART™ L15, EMOSMART™ L19, EMOSMART™ V21, EPHEMER™, ESCULANE™, FLUIDANOV™ 20X, FLUIDIPURE™ 8G, GELALG™ SPE, SEPPIC INC GULF STREAM SEA WATER, SEPPIC INC INULA HC, SEPPIC INC INULA SC, Juvenessence™, KALPARIANE™, LANOL™ 1688, LANOL™ 2681, LANOL™ 37T, LANOL™ 99, LIPACIDE™ C8G, LIPACIDE™ UG, MONTANE™ 20, MONTANE™ 481 VG, MONTANE™ 60, MONTANE™ 70, MONTANE™ 80 VG, MONTANE™ 83 VG, MONTANOV™ 14, MONTANOV™ 202, MONTANOV™ 68 MB, MONTANOV™ 82, MONTANOV™ L, MONTANOV™ S, MONTANOX™ 20 DF, MONTANOX™ 60 DF, MONTANOX™ 80 VG DF, NATIVE ESSENCE™, OLEAPHYCOL™ FV, OLEAPHYCOL™ LD, Oligogeline™ PF, OLIGOPHYCOCORAIL® SPE, ORAMIX™ CG110, ORAMIX™ L 30, ORAMIX™ NS10, ORONAL™ LCG/E OD, TECA™, PHLOROGINE™ BG PF, PHYCOBOREANE™ 2C, PHYCOCORAIL™, PHYCOL™ CC BG PF, PHYCOL™ CM BG PF, PHYCOL™ EC BG PF, PHYCOL™ FV BG PF, PHYCOL™ LD BG PF, PHYCOL™ PC BG PF, PHYCOL™ UL BG PF, PHYCOL™ UP BG PF, PHYTO-AGE™, PROTEOL™ APL EF, PROTEOL™ OAT PF, RHODYSTEROL™ S, Rosabora™, SCULPTOSANE™, SEA LAVENDER HC®, SEPPIC INC SEA LAVENDER SC, SEA MAYWEED SC™ SC, SEA SATIN™, SEA STARWORT BG®, SEA STARWORT OIL®, SEAMOSS™ BG PF, Sel Grain™, SENSANOV™ WR, SEPICALM™ S WP, SEPICALM™ VGWP, SEPICAP™ MP, SEPICIDE™ HB, SEPICIDE™ LD, SEPICLEAR™ G7, SEPICONTROL™ A5, SEPIFEEL™ ONE, SEPIGEL 305™, SEPILIFT™ DPHP, SEPIMAT™ H10, SEPIMAT™ H10 FW, SEPIMAT™ HBV, SEPIMAT™ P, SEPIMAT™ SB, SEPIMAX™ ZEN, SEPINOV™ EMT 10, SEPINOV™ WEO, SEPIPLUS™ 265, SEPIPLUS™ 400, SEPIPLUS™ S, SEPIPRESS™ M, SEPITONIC™ M3.0, SEPITONIC™ M4, SEPIWHITE™ MSH, SEPIWHITE™ MSH QD, SEPPIC™ Ambiaty Extract, SEPPIC™ AMINAT - G, SEPPIC™ Asiaticoside, SEPPIC INC Micro Algue 80, SEPPIC INC Spiruline Ap, SESAFLASH™, SIMULGEL™ 600, SIMULGEL™ EG, SIMULGEL™ EPG, SIMULGEL™ FL, SIMULGEL™ I-NS 100, SIMULGEL™ NS, SIMULGEL™ SMS 88, SIMULQUAT™ HC 305, SIMULSOL™ 1292 DF, SIMULSOL™ 1293, SIMULSOL™ 165, SIMULSOL™ 220 TM, SIMULSOL™ 58, SIMULSOL™ 68 PHA, SIMULSOL™ 98, SIMULSOL™ CS, SOLAGUM™ AX, SOLAGUM™ TARA, SUPERPHYCO-D™ BG PF, TALADVANCE™, THALASSINE 2G® Thalassine 2G®, TIMECODE™, VOLUFORM™, SEPPIC INC Asiatic acid, SEPPIC INC Embelia Extract, SEPPIC INC Heterosides, SEPPIC INC Madecassoside, SAKADIKIUM™, EQUIBIOME™, SEPILIFE™ NUDE, XYLISHINE™, AMBRE OCEANE® 2C, AMONYL™ 380 BA, SEPPIC INC Flakes of Chondrus Crispus, LANOL™ 14M, LANOL™ P, ORAMIX™ GB 10, SEPIVITAL™, SUBLIGANA™
SEPPIC Beauty Care Brochure
Brochure
Products: ADIPOLESS™, ADIPOSLIM™, ALARIANE®, AMBRE OCEANE® SPE, AMONYL™ 675SB, Antileukine™ 6, AQUAXYL™, BIOENERGIZER™ P BG PF, BIOEXTENDER® SPE, BIOPLASMA™ BG 40, BIOPLASMA™ FA, BIORESTORER™ PF, SEPPIC INC BLUE SEAKALE HC, BLUE SEAKALE SC™, CAPIGEL™ 98, CELTOSOME™ Crithmum Maritimum, CELTOSOME™ Eryngium Maritimum, CERAMOSIDES™ HP, Cire De Lanol CTO™, CODIAVELANE™ BG PF, CONTACTICEL™, EASYNOV™, EMOGREEN™ L15, EMOGREEN™ L19, EMOSMART™ C28, EMOSMART™ L15, EMOSMART™ L19, EMOSMART™ V21, EPHEMER™, ESCULANE™, FLUIDANOV™ 20X, FLUIDIPURE™ 8G, GELALG™ SPE, SEPPIC INC GULF STREAM SEA WATER, SEPPIC INC INULA HC, SEPPIC INC INULA SC, Juvenessence™, KALPARIANE™, LANOL™ 1688, LANOL™ 2681, LANOL™ 37T, LANOL™ 99, LIPACIDE™ C8G, LIPACIDE™ UG, MONTANE™ 20, MONTANE™ 481 VG, MONTANE™ 60, MONTANE™ 70, MONTANE™ 80 VG, MONTANE™ 83 VG, MONTANOV™ 14, MONTANOV™ 202, MONTANOV™ 68 MB, MONTANOV™ 82, MONTANOV™ L, MONTANOV™ S, MONTANOX™ 20 DF, MONTANOX™ 60 DF, MONTANOX™ 80 VG DF, NATIVE ESSENCE™, OLEAPHYCOL™ FV, OLEAPHYCOL™ LD, Oligogeline™ PF, OLIGOPHYCOCORAIL® SPE, ORAMIX™ CG110, ORAMIX™ L 30, ORAMIX™ NS10, ORONAL™ LCG/E OD, TECA™, PHLOROGINE™ BG PF, PHYCOBOREANE™ 2C, PHYCOCORAIL™, PHYCOL™ CC BG PF, PHYCOL™ CM BG PF, PHYCOL™ EC BG PF, PHYCOL™ FV BG PF, PHYCOL™ LD BG PF, PHYCOL™ PC BG PF, PHYCOL™ UL BG PF, PHYCOL™ UP BG PF, PHYTO-AGE™, PROTEOL™ APL EF, PROTEOL™ OAT PF, RHODYSTEROL™ S, Rosabora™, SCULPTOSANE™, SEA LAVENDER HC®, SEPPIC INC SEA LAVENDER SC, SEA MAYWEED SC™ SC, SEA SATIN™, SEA STARWORT BG®, SEA STARWORT OIL®, SEAMOSS™ BG PF, Sel Grain™, SENSANOV™ WR, SEPICALM™ S WP, SEPICALM™ VGWP, SEPICAP™ MP, SEPICIDE™ HB, SEPICIDE™ LD, SEPICLEAR™ G7, SEPICONTROL™ A5, SEPIFEEL™ ONE, SEPIGEL 305™, SEPILIFT™ DPHP, SEPIMAT™ H10, SEPIMAT™ H10 FW, SEPIMAT™ HBV, SEPIMAT™ P, SEPIMAT™ SB, SEPIMAX™ ZEN, SEPINOV™ EMT 10, SEPINOV™ WEO, SEPIPLUS™ 265, SEPIPLUS™ 400, SEPIPLUS™ S, SEPIPRESS™ M, SEPITONIC™ M3.0, SEPITONIC™ M4, SEPIWHITE™ MSH, SEPIWHITE™ MSH QD, SEPPIC™ Ambiaty Extract, SEPPIC™ AMINAT - G, SEPPIC™ Asiaticoside, SEPPIC INC Micro Algue 80, SEPPIC INC Spiruline Ap, SESAFLASH™, SIMULGEL™ 600, SIMULGEL™ EG, SIMULGEL™ EPG, SIMULGEL™ FL, SIMULGEL™ I-NS 100, SIMULGEL™ NS, SIMULGEL™ SMS 88, SIMULQUAT™ HC 305, SIMULSOL™ 1292 DF, SIMULSOL™ 1293, SIMULSOL™ 165, SIMULSOL™ 220 TM, SIMULSOL™ 58, SIMULSOL™ 68 PHA, SIMULSOL™ 98, SIMULSOL™ CS, SOLAGUM™ AX, SOLAGUM™ TARA, SUPERPHYCO-D™ BG PF, TALADVANCE™, THALASSINE 2G® Thalassine 2G®, TIMECODE™, VOLUFORM™, SEPPIC INC Asiatic acid, SEPPIC INC Embelia Extract, SEPPIC INC Heterosides, SEPPIC INC Madecassoside, SAKADIKIUM™, EQUIBIOME™, SEPILIFE™ NUDE, XYLISHINE™, AMBRE OCEANE® 2C, AMONYL™ 380 BA, SEPPIC INC Flakes of Chondrus Crispus, LANOL™ 14M, LANOL™ P, ORAMIX™ GB 10, SEPIVITAL™, SUBLIGANA™
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