SEPPIC INC Madecassoside
Producer: SEPPIC INC
Madecassoside is a powerful soothing dermo-cosmetic active for atopic & psoriasis prone skin, made of highly purified Centella asiatica. It is an active ingredient for use in anti-aging, sensitive skin, very dry skin and mature skin applications. Madecassoside activates collagen expression, it provides normalization of hyperproliferation of keratinocytes, global anti-inflammatory properties and a visible effect on excessive desquamation.
Product Resources
Knowde Enhanced TDS
Identification & Functionality
INCI Name
Cosmetic Ingredients Functions
Technologies
Features & Benefits
Labeling Claims
Origin
Plant Origin
Applications & Uses
Markets
Bath & Shower Applications
Hair Care Applications
Treatment Products
Use Level
0.2-0.5%
Mode of action
- ECM restructuration (Col I & Col III up to +49%)
- Respect of essential cell functions (TNF-α & NFkB activation; SKALP: -60%; free radicals: -70%)
- Normalization of keratinocytes hyperproliferation
- Soothing effect (MMP-1: -61%)
Properties
Ingredient Origin
Physical Form
Physical Form
Powder
Soluble in
Water
Typical Properties
| Value | Units | Test Method / Conditions | |
| Purity | min. 95 | % | - |
Technical Details & Test Data
Efficacy Studies
- Itching sensation -65%
- Erythema reduction -25.7%
- Desquamation area reduction- 43.5%
- Efficacy on atopic / psioriasis-prone skin from D14:
- Soothing effect (Inflamm’Aging) / itching reduction up to 70%
- Anti-redness (erythema reduction up to -25,7%)
- Moisturizing effect (desquamation & PASI score reduction -43.5%)
- Smoothing effect (Roughness score)
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