Tri-Solve® is a skin barrier recovery agent obtained by encapsulation by high pressure homogenization of Trehalose, Ceramides and Cholesterol into a lipophilic vesicles constituted by Lecithin. It is the best combination of ingredients likely to be close to the composition of the cutaneous hydrolipid mantle, repairing it in case of damage. Enriched by a wetting agent such as trehalose, able to increase the rate of hydration in the stratum corneum. Specifically designed for skin disequilibrium and dryness.

INCI Name: Ceramide NS, Cholesterol, Hydrogenated Lecithin, Trehalose

Functions: Emollient, Moisturizing Agent, Skin Barrier Protectant

Ingredient Origin: Plant Origin

Labeling Claims: Clean at Sephora, Credo Clean Standard, Preservative-free, Ulta Beauty's Conscious Beauty

Certifications & Compliance: Halal

Benefit Claims: Barrier Function Improvement, Emolliency, Encapsulated Actives, Moisturizing, Tewl Reduction

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Knowde Enhanced TDS

Identification & Functionality

Carrier
Ingredient Origin
Origin

Gel obtained by encapsulation by high pressure homogenization of Trehalose and Ceramides into lipophilic vesicles constituted by Lecithin and Cholesterol.

Features & Benefits

Product Features
  • Triple action in skin barrier recovery: recovery, fortifying, hydration enhancement
  • Reduces TEWL (Trans Epidermal Water Loss) promoting water retention 
  • Effective hydrating properties
  • Assures long lasting hydration
  • Restores skin barrier reducing the TEWL  and increases hydration 

Indications

  • For all disorders related to damaged skin barrier (atopic dermatitis, contact and allergic dermatitis, psoriasis).
  • Moisturizing, softening, protective gel 
  • Skin protection (detergents, creams, gels), dry and hyperkeratosis skin conditions. TEWL reduction

Applications & Uses

Sun Care Applications
Use Level
1-3%
Suggested Use Levels
  • Softening gel-emulsions:  from 1% to 3%
  • Moisturizing Gels:  from 1% to 3%
  • W/O emulsions : from 1% to 3%
  • Skin recovery barrier cream : from 1% to 3%

Properties

Odor
Characteristic
Appearance
Viscous gel
Dispersible in
Water
Typical Properties
ValueUnitsTest Method / Conditions
Dry Residue (at 105°C)77.00-87.00%
pH (solution)4.50 - 7.50
Viscosity (at 25°C in aqueous solution)100.00 - 200.00nm
Microbiological Values
ValueUnitsTest Method / Conditions
Bacteria Countmax. 100CFU/ml
Yeasts And Molds Countmax. 10CFU/ml

Regulatory & Compliance

Certifications & Compliance

Technical Details & Test Data

Efficacy Tests

In Vivo Tests

1.  Skin moisturization (corneometer)

Sinerga S.p.A. Tri-Solve Efficacy Tests - 1

2% Trisolve is able to effcetively improve skin hydartion up to 40% more than Placebo.

2. TEWL Reduction Efficacy

Sinerga S.p.A. Tri-Solve Efficacy Tests - 2

2% Trisolve is able to reduce up to 15,1% skin TEWL in comparision to placebo.

 

Mechanism of Action

Sinerga S.p.A. Tri-Solve Mechanism of Action

Tri-Solve Composition fosters the restoration of the physiological hydro-lipidic film.

Safety & Health

Toxicological Information
  • Oral acute toxicity: ≥ 5000 mg/kg
  • Skin irritation in vitro: minimum irritant
  • Eye Irritation in vitro mild irritant
  • Skin irritation in vivo: not irritant

Packaging & Availability

Country Availability
Regional Availability
  • Canada
  • Europe
  • North America
  • USA

Storage & Handling

Storage and Handling

Keep product in a cool place away from light. Store in an air-tight container. Do not store when temperature could be higher then 25°-30°C. When stored at 2-8°C shelf-life will be enhanced and before use in final form it suggested to keep at Room Temperature.