Products in Cosmetic Actives: Anti-Wrinkle

Glacial Bay Organic Pure Marine Clay is a mineral-rich powder with natural cleansing, purifying, exfoliating, and oil absorption properties. It is ideally suited for use in various personal care and cosmetic applications. This ingredient is sustainably hand-harvested, solar dried, and powdered in British Columbia, Canada.

Trautec ReCol3 Powder - TTA1-01 is a synthetic recombinant human collagen. ‍Type III collagen is a structural protein that makes up the extracellular matrix (ECM) and provides space for cell growth with a supportive function. Type III collagen plays an important role in skin elasticity and moisturizing, and it also works significantly for scar healing and anti-aging. Trautec ReCol3 Powder - TTA1-01 was selected using highly bioactive fragments from the amino acid sequence of natural human Type III collagen, and genetic engineering techniques were used with eukaryotic yeast to construct an expression system by using biological fermentation technology.

Trautec ReCol3 Powder - TTA1-02 is a synthetic recombinant human collagen. ‍Type III collagen is a structural protein that makes up the extracellular matrix (ECM) and provides space for cell growth with a supportive function. Type III collagen plays an important role in skin elasticity and moisturizing, and it also works significantly for scar healing and anti-aging. Trautec ReCol3 was selected using highly bioactive fragments from the amino acid sequence of natural human Type III collagen, and genetic engineering techniques were used with eukaryotic yeast to construct an expression system by using biological fermentation technology.

Nuovo-Proline-16™ is a C16, C16 carboxyl derivative of the amino acid hydroxypro-line. Dipalmitoyl hydroxyproline promotes collagen synthesis and enhances skin tone. Additionally, it is an excellent moisturizer and functions as an anti-oxidant.

MacPeptide™ 3000 peptides synergize to promote synthesis of collagen and is an anti-wrinkle peptide solution that promotes collagen production, tightens the skin and reduces wrinkles. MacPeptide™ 3000 also provides moisturization and skin repair benefits.

MacDerma™ CSA can be obtained by the bark of willow trees. MacDerma™ CSA, or 2-hydroxyl-5-octanoyl benzoic acid is a lipophilized derivative of salicylic acid. The compound has corneolytic, anti-inflammatory, anti-microbial and anticomedonic activities.

MacPeptide™ Syn6 is an anti-wrinkle peptide solution that helps with wound recovery, smoothing lines and reducing wrinkles. MacPeptide™ Syn6 promotes synthesis of collagen, fibronectin, laminin and hyaluronic acid smoothing wrinkles and moisturizing the skin.

G-Hexuron is the stabilized form of Vitamin C that can be topically applied to the skin in advanced formulations specifically targeted for anti-aging and photo-protection benefits. G-Hexuron is the water soluble, Vitamin C, 2-derivative with superior formulation stability. G-Hexuron is both bioavailable and bioactive in its 2-glucoside form and has been shown to be more bio-persistent over time vs. Vitamin C. G-Hexuron is photo-protective, visibly lightens skin and possesses anti-aging properties similar to Vitamin C.

Macamin™ RL50DE is retinol and comes in three different forms: a pure crystalline form, a water miscible form, and an oil form both liquid forms are stabilized with DL Alpha Tocopherol. Retinol is a type of retinoid found in Vitamin A and when used in skin care formulations helps accelerate skin renewal, enhances collagen production, and reduces the appearance of wrinkles, uneven texture, and age spots.

MacPeptide™ Copper peptide solution contains the molecule consisting of GHK (Gly-L-His-L-Lys) and Cu and has both hair and skin benefits. MacPeptide™ Copper stimulates fibrolasts to produce collagen and mucopolysaccharide which leads to tighter, smoother skin reducing fine lines and wrinkles. It promotes the expression of hair growth factor by activating hair follicle tissues which regulates hair growth. MacPeptide™ Copper also scavenges for free radicals providing UV and anti-inflammatory protection.

Macamin™ RL50WME is retinol and comes in three different forms: a pure crystalline form, a water miscible form, and an oil form both liquid forms are stabilized with DL Alpha Tocopherol. Retinol is a type of retinoid found in Vitamin A and when used in skin care formulations helps accelerate skin renewal, enhances collagen production, and reduces the appearance of wrinkles, uneven texture, and age spots.

Macamin™ NC (Niacinamide) is vitamin B3, an essential nutrient. It provides both nutritional and topical benefits. As a skin care active, niacinamide can improve the appearance of hyperpigmented skin, reduce redness, fine lines and wrinkles, smooth skin texture and enhance skin barrier properties.

MacDerma™ ALA is found in healthy foods such as spinach, chard, collard greens and broccoli, foods often deficient in standard American diets. It is an antioxidant that is found in every human cell. MacDerma™ ALA at 5 % has been shown to reduce fine lines caused by sun damage.

MacPeptide™ AH8 is an anti-wrinkle peptide solution that improves skin elasticity by restoring the skin’s natural water barrier. It helps bind water to the skin improving dry skin. MacPeptide™ AH8 penetrates skin’s layers to reduce the appearance of wrinkles on the face. It is considered a neurotransmitter-inhibiting peptide because it may have the ability to target expression wrinkles.

Macamin™ RL is retinol and comes in three different forms: a pure crystalline form, a water miscible form, and an oil form - both liquid forms are stabilized with DL Alpha Tocopherol.Retinol is a type of retinoid found in Vitamin A and when used in skin care formulations helps accelerate skin renewal, enhances collagen production, and reduces the appearance of wrinkles, uneven texture, and age spots.

Lonza® Bioactive Functional called XPressEV™, designed to help reduce the visible effects of chronological aging leading to the appearance of firmer and “fitter” skin. XPressEV™ BioActive has been created using cutting edge technology: Supercritical CO2 extraction, which is a more environmentally friendly process than traditional extraction techniques. XPressEV™ BioActive contains extract of Morus Nigra which is rich in anti-oxidants (obtained using the Supercritical CO2 process) and Pearl extract (a biomineralized product with cosmetic beneficial properties). China approved preservative-free anti aging active.

Texiterra™ Seabuckthorn Fruit Pulp Oil is a cold pressed natural oil with a deep red color, due to its high carotene content. It is rich in omega 7 along with vitamin A and is considered an effective anti-ageing oil, reducing wrinkles and boosting collagen production. The product naturally comforts dry skin and can also deliver strength and shine to skin.

NaturePep® Ganoderma reduces crow’s feet wrinkles and roughness for smoother-looking skin. Repairs dermal degradation and prevents skin’s oxidative & cellular damage caused by aging, UV, environmental stress, and pollutants. Decreases melanin concentration on dark spots for an even skin complexion. INCI: Hydrolyzed Ganoderma Lucidum (Mushroom) Extract Suggested use level: 1 - 5%; add in the water or cool-down phase, when less than 40°C. For a formulation, the ideal pH range is 4.0 - 7.0. This product is gluten-free and non-GMO.

Fision® Instant Lift - Fast-acting, on-demand anti-aging. Uniform film provides even coverage throughout the skin. Instantly improves skin firmness, reduces the appearance of wrinkles, and smooths skin. It gives your skin instagratification for younger-looking skin. INCI: Water, Hydrolyzed Soy Protein, Acacia Senegal Gum, Xanthan Gum Suggested use level: 3 - 5%; add in the water or cool down phase. Incorporate at temperatures below 40°C. For a formulation, the ideal pH range is 4.5 - 7.0. This product is gluten-free, non-GMO, and Ecocert/Cosmos approved. Alternative Fision® SoyLift and Fision® SkinLift. These are no longer being promoted (slightly different INCI). Sold to existing customers only.

Fision® WrinkleFix fixes your wrinkles by protecting, fortifying, and renewing your skin. It is perfect for all skin types, including sensitive skin. Visibly minimizes deep wrinkles and fine lines. Reduces age spots for a more even complexion. Significant changes in wrinkles can be seen after 56 days giving brighter, and younger skin. INCI: Water, Hydrolyzed Rice Protein, Hydrolyzed Pea Protein, Glycine, Proline, Hydrolyzed Sodium Hyaluronate Suggested use level: 1 - 5%; add in the water or cool down phase. Incorporate at temperatures below 40°C. For a formulation, the ideal pH range is 4.0 - 7.0. This product is gluten-free and non-GMO.

NaturePep® Teff – Invigorate skin’s foundation by stimulating collagen and HA production. We have clinical results showing a reduction in neck sagginess after just 28 days. We also have clinical results showing that it diminishes nasolabial fold volume and wrinkle depth. NaturePep® Teff penetrates the skin and reverses fatigue by making the skin more elastic. INCI: Hydrolyzed Eragrostis Tef Seed Extract Suggested use level: 1 - 5%; add in the water or cool down phase, when less than 40°C. For a formulation, the ideal pH range is 4.0 - 6.0. This product is gluten-free and non-GMO.

NaturePep® Sacha Inchi reduces facial sagginess for contoured skin. Restructures skin by increasing dermal density. Has shown statistically significant clinical results after 21 & 28 days. Helps reduce wrinkles. Patented pending formulation is the only water-soluble version of this ingredient available. INCI: Hydrolyzed Plukenetia Volubilis Seed Extract Suggested use level: 1 - 5%; add in the water or cool down phase, when less than 40°C. For a formulation, the ideal pH range is 4.0 - 8.0. This product is gluten-free, non-GMO, and Ecocert/Cosmos approved.

DermalRx® KBGA (R10017) is a proprietary blue-green algal extract with a unique combination of naturally-occurring repair active components for skin and hair moisturization and nourishment. Derived from Aphanizomenon flos-aquae (AFA), DermalRx® KBGA is rich in essential amino acids and fatty acids, proteins, antioxidants, and a full spectrum of minerals.Backed with comprehensive efficacy assays, DermalRx® KBGA increases the skin’s ability to maintain moisture at the skin barrier while protecting collagen and other extracellular matrix components (ECM, the structural foundation of the skin) from oxidative and proteolytic stress. With optimized bioactivity and bioavailability, DermalRx® KBGA addresses dry and damaged skin with applications in anti-aging and anti-wrinkle products, and nourishing, moisturizing skin and hair formulations. 

Pleiotanicals® Volpura® EP (R10098) is an Echinacea purpurea extract to address the signs of aging by supporting the skin’s natural plumping processes. Volpura® EP activates adipogenesis (fat production) within the skin to combat the appearance of wrinkles and sagging from deep within the tissue. Volpura® EP restores fuller, youthful-looking skin by activating an adipogenic modulator that increases the number and size of fat-producing cells. Clinical studies demonstrate that Volpura® EP improves skin mechanical properties with volumizing, anti-wrinkle activity reported after use on the face and hands for 12 weeks. Volpura® EP is recommended for anti-wrinkle, anti-aging, firming, plumping, topical contouring, and volumizing products, as well as regimens to address age-related lipoatrophic disorders.

Cogesome® RL (R10115) is a novel and proprietary pro-liposome formulation that encapsulates retinol (vitamin A) for superior penetration into the skin, improved stability, and optimal miscibility in aqueous systems. The power of retinol is undisputed, accelerating epidermal renewal and enhancing collagen and hyaluronic acid production to reduce the appearance of fine lines, wrinkles, and other signs of aging and improve the skin’s overall appearance. Properly managed retinol is one of the skin’s best supporters, contributing to a healthy glow and youthful appearance.Ex vivo data demonstrate how Cogesome® RL rapidly penetrates the skin, enhancing the penetration and delivery of retinol from the skin’s surface deep into the skin to maximize efficacy. Cogesome® RL significantly reduces biofilm-forming skin resident Cutibacterium acnes, a microbial culprit of blemish flare-ups and skin inflammation. Cogesome® RL is well suited for applications in anti-aging, anti-wrinkle, and anti-blemish formulas, skin exfoliating and resurfacing products, and regimens targeting sun damage and hyperpigmentation.

DermalRx® SRC (R10001) is a yeast-derived oligopeptide that promotes skin renewal by stimulating natural exfoliation via gentle and selective desquamation. Clinical testing demonstrates that DermalRx® SRC enhances exfoliation to reduce skin roughness and improve the appearance of wrinkles in four weeks. DermalRx® SRC gently loosens coarse keratinized cells at the surface, delivering results for applications in anti-aging, anti-wrinkle, anti-blemish, skin brightening, and exfoliation products. DermalRx® SRC is clinically demonstrated to restore skin texture and radiance with documented improvements in the appearance of hyperpigmentation, wrinkles, and other signs of aging. DermalRx® SRC is a selective exfoliant for safe, effective skin renewal.

DermalRx® SRC-R (R10099) is a yeast-derived oligopeptide that promotes skin renewal by stimulating natural exfoliation via gentle and selective desquamation. Clinical testing demonstrates that DermalRx® SRC-R enhances exfoliation to reduce skin roughness and improve the appearance of wrinkles in four weeks. DermalRx® SRC-R gently loosens coarse keratinized cells at the surface, delivering results for applications in anti-aging, anti-wrinkle, anti-blemish, skin brightening, and exfoliation products. DermalRx® SRC-R is clinically demonstrated to restore skin texture and radiance with documented improvements in the appearance of hyperpigmentation, wrinkles, and other signs of aging. DermalRx® SRC-R is a selective exfoliant for safe, effective skin renewal.

GelcoPEP® PLUS Hydrolyzed Collagen is a spray-dried powder designed for nutraceutical applications. With non-irradiated features, it offers benefits such as supporting bone health and joint support. Ideal for dietary supplements, dry mixes, and powdered beverages, this collagen powder enhances products with protein enrichment for overall health and healthy-looking skin. Available in convenient sachet dosage forms.

GelcoPEP® CHD Hydrolyzed Collagen is a spray-dried powder suitable for various applications in the nutraceuticals segment. With non-irradiated features, this collagen product is available in sachets and capsules, making it versatile for health and wellness supplements, dietary supplements, cereal bars, wine, beer, protein bars, candies, powdered mixes, tea, energy drinks, cookies, chocolates, and promoting healthy-looking skin. It comes with health benefits, supporting bone health and joint function.

Glycotensyl® is an optimized combination of two polysaccharides, namely marine alginate and biotech biosaccharide gum-4. It is dissolved in a mixture of water and vegetable propanediol. This solution instantly smooths the skin and makes it look younger, more radiant, and sublime.

Viniderm® is an extract of grape juice from Languedoc-Roussillon, rich in polyphenols, including a rare one: δ-viniferine. This extract is obtained by enzymatic bioconversion from resveratrol, inspired by a naturally occurring reaction catalyzed by the fungus Botrytis cinerea. It has preventive, curative, and anti-aging properties.

Heliopure® Skinn is a concentrated form of fucoxanthin, a carotenoid obtained through the extraction of the microalgae Phaeodactylum tricornutum. This potent ingredient is stabilized in organic jojoba oil (Simmondsia chinensis). The microalgae are cultivated in a meticulously controlled environment, utilizing Blue Technology, and exposed to natural sunlight by Algatech, an entity of the Solabia Group known for its expertise in biotechnology. Heliopure® Skin offers a unique and valuable solution for skincare applications.

FucoLife GR® is a low molecular weight polysaccharide (mean molecular weight: 11 kDa) obtained through controlled bacterial fermentation of non-GMO vegetable substrates. It contains galacturonic acid, L-fucose, and D-galactose, and is available as a powder (with a non-GMO maltodextrin carrier).

Resistress® is an extract of Sophora japonica flowers, enriched through enzymatic bioconversion into quercetin dimers. The dimerization of quercetin, a process enabled by Laccase Technology (a Solabia Patent), increases its biological activity. This makes Resistress® capable of preventing skin burnout by stimulating the systems of defense and repair, thereby fighting against premature aging, which is the main consequence of skin burnout.

Glycolift® is obtained through the optimization of the interactive properties of the polysaccharide Glycofilm®, combined with alginate, vegetable propanediol, and gluco-oligosaccharides. This product has a triple action toning effect that is anti-aging, shields against pollution, and protects the skin's microbiome.

Peptiskin® is a solution containing 40% (w/w) dry extract comprised of L-lysine and L-arginine oligopeptides with a degree of polymerization (DP) ranging from 2 to 7. It is obtained through a biotechnological process of solvent-free, enzymatic synthesis and functions as a global anti-aging peptide, acting on intrinsic skin aging.