Products in Cosmetic Ingredients: Anti-Aging Agent

Gamma-AminoButyric Acid (GABA) is a non-protein amino acid, due to all its benefits; it works as an ideal anti-aging agent ingredient. It can penetrate the skin and relax tense muscles thereby significantly reducing expression lines to achieve a fresher younger looking skin. GABA is known to act as a wound healer as well. Being a neurotransmitter inhibitor is what allows for its topical muscle tone which is mostly compared to “Botox-like” effect. Research in this topical application suggests that it then improves the skin barrier. There are GABA receptors on the skin surface. The inhibitory or excitability of GABA receptor controls the relaxation and tension of the expression muscles. GABA can quickly penetrate into the skin and activate the GABA receptors, then the tense expression muscles are relaxed, the expression lines are stretched.

Glyceryl glucoside is a conjugated molecule of glycerol and glucose and was originally found to be critical for cyanobacteria survive in extreme conditions. Recently, many scientific reports suggested the key role of glyceryl glucoside in induction of aquaporin-3 protein, which is an essential protein in water molecule transport across the skin cell membrane. Glyceryl glucoside is becoming the new molecule for next generation of moisturizing ingredient.

Ascorbyl Glucoside is a derivate of ascorbic acid commonly known as Vitamin C. This stable form of Vitamin C is combined with glucose and has formidable antioxidant and works well with replenishing ingredients to preserve key substances the skin needs as to achieve a smoother, brighter and younger look. Additionally, it is an essential discoloration inhibitor.

Mandelic acid is larger than Glycolic acid, the most popular alpha hydroxyl acid, which makes it better tolerated on the skin. Mandelic acid belongs to a group of AHAs known as aromatic alpha hydroxyl acids, and is the smallest aromatic AHA. Mandelic acid has long been used in the medical community as an antibacterial, particularly in the treatment of urinary tract infections, as well as an oral antibiotic.

iSun L 150 is a broad spectrum UV absorber, absorbing UVB as well as UVA rays. UV radiation is an important cause of premature aging of the skin and in the development of melanoma and other forms of skin cancer.

Ferulic acid is a phenolic derivative found in the cell walls of plants such as wheat, rice, peanuts, oranges and apples. It seems to be particularly abundant in coffee and amaranth. It is an antioxidant that can seek and destroy several different types of free radical - ‘superoxide’, ‘hydroxyl radical’, and nitric oxide. Ferulic acid is suggested to suppress melanin generation by antagonizing tyrosine because its chemical structure is similar to tyrosine. Synergizes with other antioxidants especially vitamins C and E. When used with these vitamins, prevents them from breaking down or becoming ineffective. This super antioxidant has also been shown to protect against a variety of cancers, bone degeneration, and menopausal symptoms such as hot flashes.

Glycolic acid is used in the pharmaceutical industry as a skin care agent. Glycolic acid derived from plants – such as sugar cane, pineapple and sugar beets - its botanical properties help to treat skin conditions such as Psoriasis and Seborrheic keratosis.

Ceramide is the main component of the stratum corneum of the epidermis layer of human skin. Together with cholesterol and saturated fatty acids, ceramide creates a water-impermeable, protective organ to prevent excessive water loss due to evaporation as well as a barrier against the entry of microorganisms. The stratum corneum is composed of 50% ceramides, 25% cholesterol, and 15% free fatty acids. With aging there is a decline in ceramide and cholesterol in the stratum corneum of humans, which leads to dry skin and irritation. iActive Cerasterol is a complex of Ceramide NP, Cholesterol and Sphingolipids present in human skin. This product helps to repair the skin barrier function, improve skin hydration and reduce TEWL.

Polyglutamic Acid (PGA) is classified as a long lasting natural moisturizer with whitening properties. This multi-functional and biodegradable polymer is water soluble. PGA has proven to be a better moisturizer than that of hyaluronic acid and collagen protein as it restores skin elasticity and smooth skin wrinkles. Additionally, this anionic amino acid can it provide smoothness, silkiness, protection against external aggressions and provide soothing response against allergies and inflammations.

Ceramide is the main component of the stratum corneum of the epidermis layer of human skin. Together with cholesterol and saturated fatty acids, ceramide creates a water-impermeable, protective organ to prevent excessive water loss due to evaporation as well as a barrier against the entry of microorganisms.The stratum corneum is composed of 50% ceramides, 25% cholesterol, and 15% free fatty acids. With aging there is a decline in ceramide and cholesterol in the stratum corneum of humans, which leads to dry skin and irritation. iActive Ceramide is an oil soluble complex of Ceramide 1, Ceramide 2, Ceramide 3, Ceramide 4 and Ceramide 6 present in human skin. This product helps to repair the skin barrier function, improve skin hydration and reduce TEWL. It is also effective for improving hair hydrophobicity and smoothness.

iSun Sucrapeptide is 100% natural sunscreen obtained by extraction from the roasted coffee biomass of the Arabica species. iSun Sucrapeptide is composed of a mixture of melanoidins, which are still formed in the coffee bean when it is submitted to roasting.

Sea Satin™ is an oil soluble marine plant extract based off Beta Maritima better known as the Sea Beet. Known for its ability to provide treatment from the root to the tip of the hair, Sea Satin® increases the volume, shine, silky feel and, suppleness. With protection from oxidative stress and other factors which cause hair aging, hair loss and scalp irritation, Sea Satin™ restructures the hair.

ANTILEUKINE™ 6 is a global anti-aging and defense shield that reduces the release of inflammation mediators. It is also a DNA protector after UVA/UVB exposure. It comes from a golden seaweed: Laminaria ochroleuca.

Juvenessence™ is an anti-aging active ingredient that is a downregulator of progerin for mature skin: -79%. It assures a detoxifying action through proteasome stimulation. It is a skin protector that reverses the age effects. It comes from the Arctic winged kelp Alaria esculenta. It lives in extreme conditions in agitated but transparent waters where sea pressure can exceed 6T/m².

Thalassine 2™ G is a Sea chamomile extract with unique skin relaxing properties. Its targeted action on substance P and acetylcholine help quickly reduce the appearance of expression lines and wrinkles. Thalassine 2G® is water soluble and preservative free.

Bioplasma FA is a combination of plankton extract from the Sahel region of Africa combined with arginine ferulate. The combination of the Plankton extract with the arginine offer 2 mechanisms to provide optimal cell detoxification.

VOLUFORM™ is the Aminovector™ solution for lifting the skin. Derived from Isoleucine, an essential amino acid known for its ability to support tissue repair and lift vital proteins on the skin. VOLUFORM™ is a natural alternative to lipofilling as it has the ability to fill wrinkles and reshape volume of the cheeks. The “volufirming technology” works to: plump, targeting the adipocytes for cellular volume and firm, targeting the fibroblasts to restore the dynamic contractile strength. Facial skin has improved elasticity. Also effective for bust volume for push up effect.

Heterosides is a highly purified water-soluble extract of Centella asiatica for skin barrier function improvement. This product provides stratum corneum formation enhancement, tight junctions reinforcement, differentiation normalization and activation of the deeper layers of the epidermis. Its anti-wrinkle effect has been recently demonstrated on the crow’s feet. Significant TEWL reduction on volunteers with a dry skin has been also observed. This is a titrated blend of the glycosylated triterpens Asiaticoside and Madecassoside. This is an active ingredient for use in intense skin care applications for dry and dehydrated skin, as well as mature skin. It comes as a crystalline powder.

AQUAXYL™, the power of a patented sweetened combination, optimizes the skin's hydrous flow. Its mechanism of action identified by cosmetogenomics, controls water circulation and reserves. “Anti-dehydration shield” action: Aquaxyl reinforces the synthesis of essential lipids and proteins involved in the organization of the corneus layer.

Concentrated extract of sugars from the rhizomes of Hedychium coronarium, SAKADIKIUM™ offers wide skin benefits. It acts as a multiprotector when exposed to blue light, UV and pollution.

Extracted from a rare halophytic plant: Crithmum maritimum (or sea fennel) which can be found in salty soils on the Brittany coasts. It offers a global protection, oxygenation and radiance for beautiful skin.

Triple action cell chrono-energizing and anti-free radical agent designed for skin and hair care. SEPITONIC™ M3 is active at all age for vitality, skin aging prevention and protection against stress and pollution. SEPITONIC™ M3.0 visibly improves skin texture and reduces deep wrinkles by increasing the oxygen immediately available to the skin + 14% after 30min. SEPITONIC™ M3.0 stimulates energy release with +34% ATP synthesis after 6hrs & 24hrs

BIOPLASMA™ BG: detoxifying & anti-stress. BIOPLASMA™ BG is an extract from Scenedesmus Sahel culture. The Scenedesmus is a phytoplankton constituted of unicellular algae, also known as microalgae from the desert. Thanks to an original morphological & pigmentary equipment, Scenedesmus Sahel resists despite of the strong irradiation. If phytoplankton protects itself from UV, it might contribute to protect the skin against oxydation.

Blue Seakale SC is an oil soluble marine plant extract from derived from Crambe maritime also known as Sea Kale. Blue Seakale SC works to stimulate cell renewal and protect epidermal stem cells and integral parts of the epidermis from external stresses such as UV.

AMBRE OCEANE™ SPE is an active ingredient that comes from Pelvetia canaliculata, a brown seaweed whose main components are sugars. Pelvetia canaliculata lives on the upper part of the beach, where the tides cover not on a daily basis but each two weeks. Pelvetia is exceptionally resistant to water shortage and has the capacity to retain water thanks to polysaccharides.

EPHEMER™ is an oil soluble brown algae extract which is the world’s 1st technology of macroalgae cell culture. EPHEMER™ has the ability to provide an immediate (24 hours) and long lasting (8 days) antioxidant effect on cells proven through in-vivo testing after 28 days. The mitochondrial DNA where the maternal genes are located is protected. After 2 months (in-vivo) the microrelief and roughness on the skin is reduced.

An oily active from the Sea Lanvender marine plant, or Immortal Blue, SEA LAVENDER SC, provides to the skin the soothing effect of Lavender, but also the anti aging properties of this immortal plant: it stimulates the synthesis of collagen, GAGs & hyaluronic acid, boosts cell renewal and cell communication. The skin is refilled and rejuvenated, with a significant improvement of moisturization in vivo.

ASPAR’AGE™ is an extract of Asparagopsis armata, a red seaweed that contains Mycosporine-like aminoacids (MAA). It contributes into the regulation of the effect of “Senescence Messaging Secretome” in order to reduce contagious aging effect on young cells.

CERAMOSIDES™ HP acts as a high-performance anti-aging shield. Ceramides are rich in omega 3, 6 and 9 and moisturize and protect the skin from losing its elasticity and firmness. Pores are tightened and skin texture is visibly refined. This unique patented complex is naturally biomimetic for perfect skin.

SEPILIFT™ DPHP is a Lipoaminoacid hydroxyproline biovector with anti-aging properties, moisturizing, firming and restructuring. It moisturizes and smoothes the signs of age (effectiveness proven in vivo :reduction of wrinkles : -32% versus placebo). It firms the tissues by stimulating the contraction of collagen fibers, by protecting the skin fibers from enzymatic lysis and by protecting frmo free radicals. Multiple modes of action against the markers of skin aging. Effectiveness proven on volunteers compared to a recognized anti-aging reference product.

CELTOSOME™ Eryngium Maritimum is an exclusive marine plant stem cell culture designed to help boost the regeneration of aging skin. Its specific activity targeting the Epidermal-Dermal Junction helps increase elastin and collagen synthesis and regulate epidermis renewal for a plumped, firmed, more radiant looking skin. This all natural ingredient in powder form is 100% active, solvent and preservative free, and compliant with Ecocert and Cosmos.

TIMECODE™ is the best ally against inflamm’aging, it targets the aging key markers. Lifted and firmed up, the skin reveals a new radiance! Proven effect after 1 month and a half of application compared to a recognized market reference product.

Madecassoside is a powerful soothing dermo-cosmetic active for atopic & psoriasis prone skin, made of highly purified Centella asiatica. It is an active ingredient for use in anti-aging, sensitive skin, very dry skin and mature skin applications. Madecassoside activates collagen expression, it provides normalization of hyperproliferation of keratinocytes, global anti-inflammatory properties and a visible effect on excessive desquamation.

SEA MAYWEED SC™ regulates the sensation of discomfort and local inflammation. Its properties come from Matricaria maritima (also named "scentless Chamomille") that is mainly located on the top of sandhills. It is distinguished by its white daisy-like flowers & its finely divided fern-like leaves.

KALPARIANE™ helps improve the firmness of the skin. It comes from Alaria esculenta, a brown algae exposed to stresses from the ocean's waves and from living in a light-deficient environment. To counterbalance these stresses, the algae has adapted to survive, achieving molecules rich in nutrients ideal for skin nutrition, protection, and suppleness. KALPARIANE™ has superior anti-aging action, maintaining cell communication at the epidermic level by activating connections 43 for an optimum keratogenesis.

Optimum Life Angelica To look beautiful, skin has to be healthy, and therefore functioning correctly. By strengthening skin cells’ vital functions, Optimum Life Angelica - active angelica plant cells - maintains their overall long-term capacity to function correctly, despite the damaging effects of natural aging and environmental stress. For balanced, radiant, younger-looking skin.