Products in Solvents & Solubilizers: Injectables

KLEPTOSE® HPB Oral Grade is a solubilizer and stabilizer for pharmaceutical and nutraceutical oral dosage applications. Applications Swallowable, chewable and effervescent tablets Lozenges Hard and soft capsules Orally dissolving films Blends Granules Pellets premix Medicated confectionary Syrups Suspensions Liquids Cream Paste Semi-solids Benefits Improves the solubility of poorly soluble compounds Can be used for taste masking of bitter or unpleasant active ingredients

Kolliphor® P 188 micro Geismar is a versatile product that caters to healthcare and pharmaceutical applications, supporting various drug delivery methods like creams, dispersions, emulsions, foams, injectables, soft gels, and transdermal patches.

Kolliphor® EL, a versatile pharmaceutical ingredient, boasts PEG-35 castor oil as its key component. Functioning as a plasticizer, gelling agent, matrix-forming agent, nonionic surfactant, emulsifier, and solubilizer, it finds applications in healthcare and pharma for drug delivery and care solutions. Ideal for ophthalmic, oral, parenteral, and topical applications, this liquid formulation seamlessly integrates into pharmaceutical and nutraceutical technologies. Offering a reliable solution across diverse domains, Kolliphor® EL stands out for its efficacy and adaptability in the realms of pharmaceuticals and nutraceuticals.

Kolliphor® ELP is a versatile pharmaceutical excipient featuring PEG-35 castor oil. With its roles as a plasticizer, gelling agent, matrix-forming agent, nonionic surfactant, emulsifier, and solubilizer, it plays a pivotal role in various pharmaceutical and nutraceutical applications. In healthcare and pharma, Kolliphor® ELP excels in drug delivery and care solutions, with applications in ophthalmic, oral, parenteral, and topical formulations. Presented in a convenient paste form, Kolliphor® ELP embodies cutting-edge technologies to meet the dynamic needs of the pharmaceutical industry.

Kollidon® 17 PF, a polyvinylpyrrolidone (PVP) belonging to pharmaceutical and nutraceutical technologies, serves as an anti-crystallizing agent, dispersant, solubilizer, solvent, and stabilizer. This powder form excels in healthcare and pharmaceutical applications, specifically in drug delivery and care solutions for ophthalmic and parenteral uses. With its versatile properties, Kollidon® 17 PF ensures efficient performance in preventing crystallization, dispersing substances, enhancing solubility, acting as a solvent, and providing stabilization, making it an invaluable component in pharmaceutical formulations.

Kollidon® 12 PF is available in powder form, serves as an anti-crystallizing agent, dispersant, solubilizer, solvent, and stabilizer. Positioned in the healthcare and pharma markets, it is suitable for injectables and carries the labeling claim of being pyrogen-free. Particularly applicable in ophthalmic and parenteral drug delivery and care solutions.

Kolliphor® ELP is a white to yellowish paste or cloudy liquid. It is a non-ionic solubilizer made by reacting castor oil with ethylene oxide in a molar ratio of 1:35. This is followed by a purification process. Kolliphor® ELP forms clear solutions in water and also dissolves in a wide range of organic solvents, such as ethanol, n-propanol, isopropanol, ethyl acetate, chloroform, carbon tetrachloride, trichloroethylene, toluene and xylene.

Kolliphor® HS15 is a yellowish white paste at room temperature that becomes a liquid at approximately 30°C. It dissolves in water, ethanol and 2-propanol to form clear solutions. Its solubility in water decreases with increasing temperatures. It is insoluble in liquid paraffin.

Kolliphor® P 188 Micro Geismar is supplied as white to slightly yellowish microbeads. It is readily soluble in water and ethanol and other mainly polar solvents. It is insoluble in ether, paraffin and fatty oils.

These functional lipid excipients act as solubilizers and emulsifiers in oral drug delivery systems. CAPMUL excipients are recognized as the ideal starting point when formulating BCS Class II & IV (poorly water soluble) and BCS Class III & IV (poorly permeable) molecules. Lipid-based drug delivery systems may be formulated as liquid or semi-solid formulations for oral dosage forms. It is manufactured in USA.

Vitamin ETPGS (NF Grade) is a water soluble form of Vitamin E suitable for nutraceutical, pharmaceutical and personal care from a natural source. Vitamin E Tocopheryl Polyethylene Glycol Succinate (TPGS) is widely used as an excipient in drug formulations and is rapidly expanding into the beverage and functional food markets. Structure - property relationship suggests that it uniquely meets the need for enhancing drug solubility, permeability, safety and enhancing the bioavailability.

Cyclolab Gamma-cyclodextrin is 8 linked D-glucopyranose units. Its unique functional characteristics make it useful for filtering out cholesterol molecules, which get trapped in the cyclodextrin rings.

Huangshan Bonsun Pharmaceuticals Polyvinylpyrrolidone K15 is a White or milky white hygroscopic powder; colorless, non-toxic, non-irritating; -easily soluble in water and a variety of organic solvents, insoluble in acetone, ether; with excellent solubility, film-forming properties, physiological compatibility, Chemical stability and adhesion.

NKY Pharma NKY 2P is completely miscible with most solvents including water, alcohol, diethyl ether, chloroform, benzene acetate and carbon disulfide; Exist as liquid above250C; Used as an intermediate in the manufacture of polymers such as polyvinylpyrrolidone and polypyrrolidone, and the raw material of acetamide pyrrolidone (piracetam) andγamino-butyric acid.

KoVidone® K17 are an essential ingredient to formulating highly effective pharmaceutical products. The polymers are produced in a state of the art manufacturing facility operating under full cGMP compliance. In addition, all physical handling and packaging of powders is conducted in class-D clean rooms with specific attention placed on reducing the risk of any potential particulate/foreign matter contamination. KoVidone® K series products possess excellent binding, film-forming, dispersing and thickening properties and are widely used.

Cyclolab Alpha-cyclodextrin is a hexasaccharide derived from glucose. It is related to the β- (beta) and γ- (gamma) cyclodextrins, which contain seven and eight glucose units, respectively. All cyclodextrins are white, water-soluble solids with minimal toxicity.

KoVidone® K12 are an essential ingredient to formulating highly effective pharmaceutical products. The polymers are produced in a state of the art manufacturing facility operating under full cGMP compliance. In addition, all physical handling and packaging of powders is conducted in class-D clean rooms with specific attention placed on reducing the risk of any potential particulate/foreign matter contamination. KoVidone® K series products possess excellent binding, film-forming, dispersing and thickening properties and are widely used.