Products in Pharmaceuticals & Nutraceuticals: Injectables

LYCADEX® PF is a pyrogen-free dextrose monohydrate that can be used: as isotonic agent in Rx excipients and in injectable applications including large volume parenteral, total parenteral nutrition as a carbohydrate source and osmotic agent for hemodialysis and peritoneal dialysis

PEARLITOL® PF is a pyrogen-free mannitol that is used for parenteral preparations and Rx injectables. Applications Osmotic diuretic agent in small and large volume parenteral injectables Isotonic agent and bulking agent for freeze-dried powder for Rx injection or infusion Pharmaceutical API used to reduce elevated pressure in the brain (cerebral oedema) and in the eyes (note: production has to comply with the internationally accepted GMP standards)

KLEPTOSE® HPB Oral Grade is a solubilizer and stabilizer for pharmaceutical and nutraceutical oral dosage applications. Applications Swallowable, chewable and effervescent tablets Lozenges Hard and soft capsules Orally dissolving films Blends Granules Pellets premix Medicated confectionary Syrups Suspensions Liquids Cream Paste Semi-solids Benefits Improves the solubility of poorly soluble compounds Can be used for taste masking of bitter or unpleasant active ingredients

KLEPTOSE® HPB Biopharma Hydroxypropyl Betadex Cyclodextrin is a low endotoxin grade materials that provides protein stabilization for biopharmaceutical downstream applications. With a hydrophobic internal cavity and hydrophilic exterior, KLEPTOSE® HPB BioPharma can encapsulate molecules, forming inclusion complexes where lipophilic compounds are non-covalently bound within the cavity. It is suitable for use in biopharmaceutical manufacturing and as an excipient for injectable dosage forms. Benefits Unique ability to encapsulate and shield water insoluble materials can be utilized to shield exposed hydrophobic residues on aggregation-prone proteins, thereby modulating protein aggregation Shows promise as a multifunctional excipient suitable for biopharma applications Can serve as a tool to synergistically complement biotherapeutic formulations Multicompendial material (EP, USP, JP) Features Starch derivative Cyclic oligosaccharide with a bucket-like structure

NEOSORB® PF pyrogen-free sorbitol is used: as a carbohydrate source and osmotic diuretic agent in large-volume parenteral injectables as an isotonic agent for Rx injectables as an irrigating fluid for surgical procedures, to prevent intra- and extra-cellular dehydration

Kolliphor® P 188 micro Geismar is a versatile product that caters to healthcare and pharmaceutical applications, supporting various drug delivery methods like creams, dispersions, emulsions, foams, injectables, soft gels, and transdermal patches.

Kolliphor® EL, a versatile pharmaceutical ingredient, boasts PEG-35 castor oil as its key component. Functioning as a plasticizer, gelling agent, matrix-forming agent, nonionic surfactant, emulsifier, and solubilizer, it finds applications in healthcare and pharma for drug delivery and care solutions. Ideal for ophthalmic, oral, parenteral, and topical applications, this liquid formulation seamlessly integrates into pharmaceutical and nutraceutical technologies. Offering a reliable solution across diverse domains, Kolliphor® EL stands out for its efficacy and adaptability in the realms of pharmaceuticals and nutraceuticals.

Kolliphor® ELP is a versatile pharmaceutical excipient featuring PEG-35 castor oil. With its roles as a plasticizer, gelling agent, matrix-forming agent, nonionic surfactant, emulsifier, and solubilizer, it plays a pivotal role in various pharmaceutical and nutraceutical applications. In healthcare and pharma, Kolliphor® ELP excels in drug delivery and care solutions, with applications in ophthalmic, oral, parenteral, and topical formulations. Presented in a convenient paste form, Kolliphor® ELP embodies cutting-edge technologies to meet the dynamic needs of the pharmaceutical industry.

Kollidon® 17 PF, a polyvinylpyrrolidone (PVP) belonging to pharmaceutical and nutraceutical technologies, serves as an anti-crystallizing agent, dispersant, solubilizer, solvent, and stabilizer. This powder form excels in healthcare and pharmaceutical applications, specifically in drug delivery and care solutions for ophthalmic and parenteral uses. With its versatile properties, Kollidon® 17 PF ensures efficient performance in preventing crystallization, dispersing substances, enhancing solubility, acting as a solvent, and providing stabilization, making it an invaluable component in pharmaceutical formulations.

Kollidon® 12 PF is available in powder form, serves as an anti-crystallizing agent, dispersant, solubilizer, solvent, and stabilizer. Positioned in the healthcare and pharma markets, it is suitable for injectables and carries the labeling claim of being pyrogen-free. Particularly applicable in ophthalmic and parenteral drug delivery and care solutions.

BTC Europe GmbH Dexpanthenol Ph.Eur. serves as an active pharmaceutical ingredient applicable for topical, oral, and injectable use. It demonstrates high hygroscopicity, enabling easy dissolution in water for producing liquid or semi-solid formulations. Dexpanthenol plays a vital role in enhancing wound healing, promoting epithelization, and exhibiting anti-inflammatory properties, thus finding application in local treatments. It is available in various dosage forms, such as spray, tablets, creams, ointments, eye drops, gels, syrups, capsules, soft gels, injectables, and foams, with health benefits emphasizing its anti-inflammatory attributes.

PhytoChol® Inject ensures a dependable supply of synthetic cholesterol. Tailored for injectable drug delivery and biopharmaceutical cell culture, Evonik offers two specialized grades. These grades meet the distinct requirements of each application, providing a secure and stable source for pharmaceutical and biopharmaceutical needs. With PhytoChol® Inject, Evonik delivers a versatile solution for applications demanding synthetic cholesterol, ensuring reliability and adherence to specific industry standards.

Omega-3-acid triglycerides (CN 600 TG) is a pale-yellow liquid comprised of a minimum of 30 per cent eicosapentaenoic acid (EPA) and a minimum of 20 per cent docosahexaenoic acid (DHA) presented as triglycerides (Ph. Eur. 1352 current ed.). The content of EPA and DHA triglycerides is a minimum 50 per cent and the content of total omega-3-acid triglycerides is a minimum 60 per cent. Tocopherol is added as an antioxidant. CN 600 TG is a concentrated and purified fish oil made from body oil of wild fatty fish. Alpha-tocopherol is added as antioxidant. No other additives. CN 600 TG is intended for use as an ingredient in finished formulations intended for parenteral use, for the supply of omega-3 fatty acids and energy when prescribed by a physician.

Kolliphor® HS15 is a yellowish white paste at room temperature that becomes a liquid at approximately 30°C. It dissolves in water, ethanol and 2-propanol to form clear solutions. Its solubility in water decreases with increasing temperatures. It is insoluble in liquid paraffin.

Kolliphor® ELP is a white to yellowish paste or cloudy liquid. It is a non-ionic solubilizer made by reacting castor oil with ethylene oxide in a molar ratio of 1:35. This is followed by a purification process. Kolliphor® ELP forms clear solutions in water and also dissolves in a wide range of organic solvents, such as ethanol, n-propanol, isopropanol, ethyl acetate, chloroform, carbon tetrachloride, trichloroethylene, toluene and xylene.

Kolliphor® P 188 Micro Geismar is supplied as white to slightly yellowish microbeads. It is readily soluble in water and ethanol and other mainly polar solvents. It is insoluble in ether, paraffin and fatty oils.

PhytoChol® Biopharma is a plant-based cholesterol offering essential benefits in pharmaceutical manufacturing. Categorized under healthcare and pharma, specifically pharmaceutical processing, it finds applications in injectables. With its identification as a plant-origin ingredient, PhytoChol® Biopharma serves as a cell culture nutrient in pharmaceutical and nutraceutical functions. Embrace the advantages of this bio-friendly solution, supported by labeling claims of being plant-based. Choose PhytoChol® Biopharma for a reliable and sustainable source of cholesterol in pharmaceutical applications.

ADM Dextrose Monohydrate is produced through the enzymatic hydrolysis of starch, followed by purification, concentration, crystallization, and drying. It is a white calibrated powder with a refreshing sweet taste and bland odor, complying with EU and manufacturing country directives and regulations on foods and food ingredients, considered Non GMO. Dextrose, also known as glucose, is a simple sugar derived from various botanical sources like corn, wheat, fruits, and honey. It is widely used in a variety of products, including pharmaceutical applications, owing to its versatile functionality and benefits beyond sweetness.

CERELOSE® Anhydrous Dextrose - USP Grade - 025020 is a white crystalline powder with Exceptional purity made particularly for the pharmaceutical industry. This high-quality dextrose is made under cGMP and used as an active ingredient for parenteral applications. The product will contain less than 1.25 units of endotoxin per gram by LAL test. Therefore, it meets the requirements of the United States Pharmacopeia, USP.

Cupper Gluconate is used in anti-deficiency human (rheumatic and inflammatory diseases, viral and infectious states and influenza) or veterinary therapeutic, alone or in association with other trace-elements, orally or by injection.

AllanChem Ammonium Chloride is an odorless, high-quality, inorganic crystalline powder used as a flour treating agent, viscosity modifier, fragrance ingredient, and buffering agent. It is used in pharmaceutical manufacturing, parenteral drug delivery and care solutions, bakery applications, and skin care applications.

These functional lipid excipients act as solubilizers and emulsifiers in oral drug delivery systems. CAPMUL excipients are recognized as the ideal starting point when formulating BCS Class II & IV (poorly water soluble) and BCS Class III & IV (poorly permeable) molecules. Lipid-based drug delivery systems may be formulated as liquid or semi-solid formulations for oral dosage forms. It is manufactured in USA.

Capmul® MCM C8 is composed of mono and diglycerides of medium chain fatty acids (mainly caprylic). It is an excellent solvent for many organic compounds, including steroids. It is also a useful emulsifier for water-oil systems. It is manufactured in USA.

Drakeol® 600 MIN OIL USP is a white oils are among the most versatile products in the world, making them a standard preference across diverse industries. Due to their extreme purity, white oils provide an effective use as a base, emollient, lubricant, release agent, binder, or excipient in multiple product applications.

Drakeol® 7 LT MIN OIL NF is a white oils are among the most versatile products in the world, making them a standard preference across diverse industries. Due to their extreme purity, white oils provide an effective use as a base, emollient, lubricant, release agent, binder, or excipient in multiple product applications.

Drakeol® 350 MIN OIL USP is a white oils are among the most versatile products in the world, making them a standard preference across diverse industries. Due to their extreme purity, white oils provide an effective use as a base, emollient, lubricant, release agent, binder, or excipient in multiple product applications.

Peneteck® LT MIN OIL NF is a white oils are among the most versatile products in the world, making them a standard preference across diverse industries. Due to their extreme purity, white oils provide an effective use as a base, emollient, lubricant, release agent, binder, or excipient in multiple product applications.

Drakeol® 15 LT MIN OIL NF is a white oils are among the most versatile products in the world, making them a standard preference across diverse industries. Due to their extreme purity, white oils provide an effective use as a base, emollient, lubricant, release agent, binder, or excipient in multiple product applications.

Vitamin ETPGS (NF Grade) is a water soluble form of Vitamin E suitable for nutraceutical, pharmaceutical and personal care from a natural source. Vitamin E Tocopheryl Polyethylene Glycol Succinate (TPGS) is widely used as an excipient in drug formulations and is rapidly expanding into the beverage and functional food markets. Structure - property relationship suggests that it uniquely meets the need for enhancing drug solubility, permeability, safety and enhancing the bioavailability.

Drakeol® 21 MIN OIL USP is a white oils are among the most versatile products in the world, making them a standard preference across diverse industries. Due to their extreme purity, white oils provide an effective use as a base, emollient, lubricant, release agent, binder, or excipient in multiple product applications.

Drakeol® 10 B LT MIN OIL NF is a white oils are among the most versatile products in the world, making them a standard preference across diverse industries. Due to their extreme purity, white oils provide an effective use as a base, emollient, lubricant, release agent, binder, or excipient in multiple product applications.

Drakeol® 6VR LT MIN OIL NF is a white oils are among the most versatile products in the world, making them a standard preference across diverse industries. Due to their extreme purity, white oils provide an effective use as a base, emollient, lubricant, release agent, binder, or excipient in multiple product applications.

Drakeol® 10 LT MIN OIL NF is a white oils are among the most versatile products in the world, making them a standard preference across diverse industries. Due to their extreme purity, white oils provide an effective use as a base, emollient, lubricant, release agent, binder, or excipient in multiple product applications.

Drakeol® 34 MIN OIL USP is a white oils are among the most versatile products in the world, making them a standard preference across diverse industries. Due to their extreme purity, white oils provide an effective use as a base, emollient, lubricant, release agent, binder, or excipient in multiple product applications.

Drakeol® 19 MIN OIL USP is a white oils are among the most versatile products in the world, making them a standard preference across diverse industries. Due to their extreme purity, white oils provide an effective use as a base, emollient, lubricant, release agent, binder, or excipient in multiple product applications.