Products in Pharmaceuticals & Nutraceuticals: Soft Gels

POLYSORB® 85/70/00 Partially dehydrated sorbitol liquid is a plasticizer in soft capsules and orally dissolving films. It can be used in pharmaceutical dosage forms.POLYSORB® 85/70/00 is an aqueous solution of D-sorbitol and 1.4- sorbitans that has been developed by Roquette as a plasticizer for soft gelatine capsule applications. The advantage of this product in soft gels relates to its remarkable compatibility with gelatin that ensures no migration over time thereby preventing any defects like graining when crystallizing plasticizers are used or leaching phenomena either into the filler media or at the surface of the soft gel.

PronovaPure® 360:240 TG EU is sourced from marine origin, qualifying as a natural-origin ingredient. Its primary function is as a dietary supplement. The product bears labeling claims such as being naturally derived, natural, and sustainable. It is available in capsule and liquid physical forms.

PronovaPure® 46:38 EE originates from marine sources and natural origins. This product is a light yellow concentrate of fish oil ethyl esters. Positioned within the healthcare and pharmaceutical markets, its primary function lies in the realm of dietary supplements. Labeling claims affirm its natural and sustainable properties. Available in capsules and liquid form, it complies with various certifications such as European Pharmacopeia (Ph. Eur.), FSSC 22000, Hazard Analysis Critical Control Point (HACCP), and cGMP.

Kolliphor® P 188 micro Geismar is a versatile product that caters to healthcare and pharmaceutical applications, supporting various drug delivery methods like creams, dispersions, emulsions, foams, injectables, soft gels, and transdermal patches.

Kolliphor® P 407 micro Geismar is specially designed for healthcare and pharmaceutical applications, this product is suitable for oral and topical use. Kolliphor® P 407 micro Geismar is utilized in formulations such as creams, dispersions, emulsions, foams, gels, and soft gels.

Kollidon® VA 64 Fine, a copovidone-based product, serves diverse functions in pharmaceuticals and nutraceuticals. As an anti-crystallizing agent, binder, dispersing agent, filler, film former, matrix forming agent, and moisture barrier coating, it plays a pivotal role in drug delivery and care solutions. Its applications extend to oral and topical healthcare formulations, as well as nutrition and well-being products in the food and nutrition industry. With a versatile physical form available as both powder and solid, Kollidon® VA 64 Fine embodies essential technologies for achieving optimal performance in pharmaceuticals and nutraceuticals.

PronovaPure® 460:180 EE presents as a light yellow concentrate of fish oil ethyl ester. The fish oil is sourced from anchovies, sardines, and mackerels belonging to the families Engraulidae, Clupeidae, Carangidae, and Scombridae. This product is rich in omega-3 fatty acids and is in the ethyl ester (EE) form. Its EPA (eicosapentaenoic acid expressed as EE) and DHA (docosahexaenoic acid expressed as EE) content stands at a minimum of 640 mg/g. The labeling claims highlight its non-GMO and halal attributes. It is available in the form of capsules and soft gels.

Kollisolv® MCT 70 is a versatile medium-chain triglyceride with applications in healthcare and pharma technologies. Serving as a lubricant, emollient, skin penetrant, cosolvent, and solvent, this liquid formulation excels in drug delivery and care solutions for both oral and topical applications. Ideal for pharmaceuticals and nutraceuticals, Kollisolv® MCT 70 stands as a reliable choice for enhancing product formulations.

Vegapure® 95 E plant sterol esters are acquired through the esterification process of free plant sterols with fatty acids derived from vegetable oil. This product appears as a yellow, viscous oily paste at ambient temperature and transforms into a clear oil with a typical fatty odor and taste above 50 °C. Additionally, tocopherol-rich extract and ascorbyl palmitate are incorporated as antioxidants. Functionally, it serves as a phytochemical. In its physical form, it manifests as a paste and is distinguished by its neutral taste. Vegapure® 95 E finds applications in various food and nutrition sectors, such as dairy products, dietary supplements, functional beverages, functional foods, and margarine.

Maxomega™ EPA 96 EE is an oil containing a minimum of 96% of the primary omega-3 acid eicosapentaenoic acid (EPA) in ethyl ester (EE) form. It serves as an active ingredient in pharmaceutical preparations intended for oral application, subject to approval by the relevant medicinal authority for specific indications. Due to its susceptibility to oxidation upon exposure to air, it is packaged in nitrogen-purged drums. This oil is well-suited for use as the sole filling material in soft gelatin capsules.

Kollisolv® PEG 400, a polyethylene glycol, serves as a solubilizer and solvent in pharmaceuticals and nutraceutical technologies. Ideal for healthcare and pharma applications, it facilitates drug delivery and care solutions. With versatility for both oral and topical use, this liquid product offers a reliable solution for enhancing solubility in various formulations.

Kolliphor® EL, a versatile pharmaceutical ingredient, boasts PEG-35 castor oil as its key component. Functioning as a plasticizer, gelling agent, matrix-forming agent, nonionic surfactant, emulsifier, and solubilizer, it finds applications in healthcare and pharma for drug delivery and care solutions. Ideal for ophthalmic, oral, parenteral, and topical applications, this liquid formulation seamlessly integrates into pharmaceutical and nutraceutical technologies. Offering a reliable solution across diverse domains, Kolliphor® EL stands out for its efficacy and adaptability in the realms of pharmaceuticals and nutraceuticals.

Kolliwax® CSA 50 is a versatile product in the field of pharmaceuticals and nutraceuticals. Cetearyl alcohol, its key component, serves as a matrix-forming agent, co-emulsifier, and viscosity modifier. Available in bead and solid forms, it finds application in healthcare and pharma for drug delivery and care solutions, catering to oral, rectal, and topical needs. Benefit from its advanced technologies for seamless integration into various formulations, ensuring optimal performance.

Kollisolv® PEG 300, a polyethylene glycol, serves as a versatile solvent, solubilizer, carrier, and suppository base in pharmaceuticals and nutraceuticals. With applications in drug delivery and care solutions, it is employed orally, rectally, and topically. Ideal for pharmaceutical manufacturing, it contributes to API manufacturing, excipients, and coatings. Available in a liquid form, Kollisolv® PEG 300 plays a crucial role in enhancing the efficacy and formulation flexibility in the healthcare and pharma industry.

Vegapure® 95 FF plant sterol esters are obtained through the esterification process of free plant sterols with fatty acids derived from vegetable oil. At ambient temperature, Vegapure® 95 FF appears as a viscous oily paste, transitioning into a clear oil with a typical fatty odor and taste when above 50 °C. Additionally, tocopherol-rich extract and ascorbyl palmitate are included as antioxidants. Specifically formulated for functional food and functional beverages, with a focus on margarine and dairy products as primary categories, Vegapure® 95 FF exhibits almost neutral taste and odor, making it an ideal form for integrating plant sterols into food applications.

Kollicoat® MAE 100 P is available in powder form, plays a multifaceted role as an enteric coating system, filler, film former, matrix-forming agent, and solubilizer. Its versatile applications span various dosage forms, including tablets, pellets, capsules, soft gels, and dispersions in the healthcare and pharma markets, particularly in oral drug delivery solutions.

Xangold® 15% OLV EU is a dark reddish-brown suspension that contains natural mixed carotenoid esters derived from marigold flowers (Tagetes erecta). These flowers used in manufacturing Xangold® 15% OLV EU are certified organic. This product is applicable to dietary supplements, various food products, and beverages. It functions as a phytochemical, and its active component is lutein. It bears labeling claims as plant-based, natural, organic, kosher, and naturally derived. Additionally, it holds certifications and compliance with EU standards, JECFA (FAO/WHO), and organic certification.

Kollicoat® MAE 30 DP is a methacrylic acid ethyl acrylate copolymer (1:1) designed for pharmaceutical and nutraceutical applications. As an enteric coating system and film manufacturer, it excels in drug delivery and care solutions within the healthcare and pharma industries. Available in a dispersion form, Kollicoat® MAE 30 DP is specifically tailored for oral applications, showcasing its versatility in providing effective and reliable solutions in pharmaceutical and nutraceutical technologies.

Kollicoat® Smartseal 30 D is a revolutionary pharmaceutical and nutraceutical solution. This dispersion, crafted from a copolymer of methylmethacrylate and diethylaminoethylmethacrylate, offers a natural and synthetic blend. It excels as a film former, matrix-forming agent, moisture barrier coating, and taste-masking agent. With origins rooted in plants and vegetables, it caters to the healthcare and pharma industries, specializing in drug delivery and care solutions, particularly in oral applications.

Kolliphor® RH 40, a solubilizer, emulsifier, surfactant, and solvent, utilizes PEG-40 Hydrogenated Castor Oil technology for pharmaceuticals and nutraceuticals. Ideal for healthcare and pharma applications, it excels in drug delivery and care solutions across ophthalmic, oral, and topical domains. Presenting as a versatile paste, Kolliphor® RH 40 enhances formulation efficacy in various medical contexts.

Kolliphor® ELP is a versatile pharmaceutical excipient featuring PEG-35 castor oil. With its roles as a plasticizer, gelling agent, matrix-forming agent, nonionic surfactant, emulsifier, and solubilizer, it plays a pivotal role in various pharmaceutical and nutraceutical applications. In healthcare and pharma, Kolliphor® ELP excels in drug delivery and care solutions, with applications in ophthalmic, oral, parenteral, and topical formulations. Presented in a convenient paste form, Kolliphor® ELP embodies cutting-edge technologies to meet the dynamic needs of the pharmaceutical industry.

Tonalin® TG 80 is a clear, fully transparent, colorless to slightly yellow oil at room temperature with a characteristic taste and odor. It consists of glycerides, typically containing 80% conjugated linoleic acid. Sourced from safflower oil, Tonalin® TG 80 comprises a 50:50 ratio of the active conjugated linoleic acid isomers (C18:2 c9, t11, and C18:2 t10, c12). Its primary function lies in fatty acids and lipids. The product is labeled as non-GMO, halal, and kosher and is appreciated for its neutral taste.

Kollicoat® MAE 100-55 is a versatile pharmaceutical and nutraceutical ingredient. Comprising Acrylates Copolymer and Methacrylic Acid Ethyl Acrylate Copolymer in a 1:1 ratio, it excels as an enteric coating system, filler, film former, matrix-forming agent, and solubilizer. In powder form, this technology caters to oral drug delivery and care solutions. Ideal for healthcare and pharma applications, Kollicoat® MAE 100-55 ensures efficient and reliable performance in diverse formulations.

Tonalin® FFA 80 is a clear, fully transparent, colorless to slightly yellow liquid oil at room temperature with a characteristic taste and odor. It primarily consists of free fatty acids, with approximately 80% being conjugated linoleic acid. The product is packaged in inert gas to maintain its integrity. Labeling claims affirm it as Halal and Kosher. Tonalin® FFA 80 is designed for incorporation into dietary supplements and is particularly suitable for use in dosage forms like soft gelatin capsules, which protect against oxidation for the product.

Kollisolv® P124 Geismar is tailored for healthcare and pharmaceutical applications, this versatile product is well-suited for oral and topical usage. Kollisolv® P124 Geismar is utilized in various forms like capsules, creams, emulsions, foams, gels, soft gels, and tablets.

BTC Europe GmbH Ibuprofen 38, in powder form, caters to oral and topical drug delivery solutions. The versatile dosage forms include suspensions, creams, gels, and soft gels. As a sustainable and chromate-free product, it functions as an anti-inflammatory agent. With health benefits such as analgesic, anti-inflammatory, antipyretic, and pain reduction, it serves the healthcare and pharma markets using direct compression manufacturing technology.

BTC Europe GmbH Ibuprofen 25, available in powder form, is designed for oral and topical drug delivery solutions. Its versatile dosage forms include suspensions, creams, gels, and soft gels. The product, labeled as sustainable and chromate-free, functions as an anti-inflammatory agent. With health benefits encompassing analgesic, anti-inflammatory, antipyretic, and pain reduction, it caters to the healthcare and pharma markets, utilizing direct compression manufacturing technology.

BTC Europe GmbH Dexpanthenol Ph.Eur. serves as an active pharmaceutical ingredient applicable for topical, oral, and injectable use. It demonstrates high hygroscopicity, enabling easy dissolution in water for producing liquid or semi-solid formulations. Dexpanthenol plays a vital role in enhancing wound healing, promoting epithelization, and exhibiting anti-inflammatory properties, thus finding application in local treatments. It is available in various dosage forms, such as spray, tablets, creams, ointments, eye drops, gels, syrups, capsules, soft gels, injectables, and foams, with health benefits emphasizing its anti-inflammatory attributes.

BTC Europe GmbH Ibuprofen 70, available in powder form, targets oral and topical drug delivery solutions. The product comes in a range of dosage forms, including tablets, creams, gels, and soft gels. Labeled as sustainable and chromate-free, it functions as an anti-inflammatory agent. Health benefits include analgesic, anti-inflammatory, antipyretic, and pain reduction. The product caters to the healthcare and pharma markets, utilizing both direct compression and wet granulation manufacturing technologies.

BTC Europe GmbH Ibuprofen 50, presented in powder form, is tailored for oral and topical drug delivery solutions. Its dosage forms include tablets, creams, gels, and soft gels. Labeled as sustainable and chromate-free, this product functions as an anti-inflammatory agent. Health benefits include analgesic, anti-inflammatory, antipyretic, and pain reduction. Targeting the healthcare and pharma markets, it employs both direct compression and wet granulation manufacturing technologies.

Kollisolv® PEG 400 LA is a colorless, tasteless liquid, that dissolves readily in water, ethanol, acetone, glycols, and chloroform. Kollisolv® PEG 400 LA diverse solubility makes it ideal for various pharmaceutical and cosmetic applications, excluding solubility in ether, paraffin, oils, or fats.

Kolliphor® ELP is a white to yellowish paste or cloudy liquid. It is a non-ionic solubilizer made by reacting castor oil with ethylene oxide in a molar ratio of 1:35. This is followed by a purification process. Kolliphor® ELP forms clear solutions in water and also dissolves in a wide range of organic solvents, such as ethanol, n-propanol, isopropanol, ethyl acetate, chloroform, carbon tetrachloride, trichloroethylene, toluene and xylene.

Kolliphor® P 407 Micro Geismar is supplied as white to slightly yellowish microbeads. It is readily soluble in water and ethanol and other mainly polar solvents. It is insoluble in ether, paraffin and fatty oils. It offers effective content uniformity, solubilization and increase oral bioavailability of bioactive

Kolliphor® P 188 Micro Geismar is supplied as white to slightly yellowish microbeads. It is readily soluble in water and ethanol and other mainly polar solvents. It is insoluble in ether, paraffin and fatty oils.

Kollicoat® Smartseal 30 D is insoluble in water (neutral pH) and dissolves quickly under protonation at pH-values of 5.5 and below due to the defined number of basic functional groups. It is a co-polymer comprising methyl methacrylate (MMA) and diethylaminoehtylmethacrylate (DEAEMA) in the ratio 6:4. Kollicoat Smartseal 30 D is an aqueous polymer dispersion (latex) with a faint characteristic odor. It contains approx. 0.6 % macrogol cetostearylether 20 and approx. 0.8% sodium laurylsulfate.

Maxomega EPA 96 EE is a clear, colorless-to-faint-yellow liquid containing a minimum of 96 % (w/w) EPA EE. Tocopherol is added as an antioxidant. Eicosapentaenoic acid ethyl ester is a highly concentrated, unsaturated oil. It oxidizes readily in contact with air and is, therefore, filled in drums purged with nitrogen. It is well suited for use in soft gelatin capsules as the sole fill material.