Knowde Enhanced TDS
Identification & Functionality
- Carrier
- Ingredient Origin
- Cosmetic Ingredients Functions
- Technologies
- Product Families
- Origin
- DermalRx® Acetygen® is a botanical extract that combats the environmental stressors that can gradually deteriorate skin through epigenetic modulation of genes essential for youthful skin.
Features & Benefits
- Benefit Claims
- Labeling Claims
- Benefits & Claims
- Multi-functional “pro-health” skincare active derived from an unique combination of Agrimonia eupatoria and Ampelopsis grossedentata
- Senolytic activity to battle the tissue-aging effects of senescent cells via p53 phosphorylation
- Anti-aging efficacy via broad-spectrum, multi-level epigenetic control
- Enhanced gene expression for broad anti-aging benefits of ECM regeneration & protection
- Anti-inflammatory & antioxidant activities
Applications & Uses
- Markets
- Skin Care Applications
- Sun Care Applications
- Use Level
- 1 - 3%
- Applications
- Skin health and wellness via regulation of natural skin repair mechanisms
- All anti-aging products targeting oxidative, environmental, and inflammatory damage
- Soothing and calming products for damaged skin
- Moisturizing, repair, and maintenance creams, lotions, and serums for skincare
- Adjuvant therapy to bolster proprietary actives and products
- Compatibility and Formulation
- DermalRx® Acetygen® is water miscible and compatible with most conventional ingredients used in skincare products. Add during the last steps of processing when the batch temperature is below 50°C.
Properties
- Physical Form
Regulatory & Compliance
- Certifications & Compliance
- Regulatory Information
- This product has not been tested on animals, and our company adheres to the written provisions of such animal rights organizations as Leaping Bunny and Cruelty/Free International.
- This product contains no animal products. It is manufactured using only plant based or synthetically derived (non-animal origin) materials and is thereby declared a Vegan Product.
- All materials used to produce this product are procured using sustainable sourcing practices.
- This product is manufactured in accordance with the current Good Manufacturing Practices (cGMP) requirements established by the U.S. Food and Drug Administration (FDA) for cosmetics. Furthermore, Biocogent, LLC, and this production facility(ies), are registered as cosmetic manufactures with the FDA.
- REACH compliance: All of the ingredients (substances) used in the manufacture of this product (mixture)are either registered under REACH, or qualify for an Article 2 (low volume of less than 1 metric ton), Annex IV or Annex V exemption, making our product REACH compliant.
- Proposition 65 compliance: Based upon Biocogent LLC’s knowledge of our business operations and chemical formulations, no chemicals listed by the State of California Environmental Protection Agency are used in our products, or as a processing aid for any product manufactured in our facility.
Technical Details & Test Data
- Test Data
DermalRx® Acetygen® Inhibition of Histone Deacetylation (HDAC)
DermalRx® Acetygen® acts as an HDAC inhibitor, preserving histone acetylation to reduce gene silencing and enhance the expression of beneficial genes.
Safety & Health
- Safety
- Human Repeat Insult Patch Testing (HRIPT) under semi-occlusive conditions indicated that DermalRx® Acetygen® is not a primary skin irritant or a primary skin sensitizer when tested neat. Ocular irritation testing predicted that DermalRx® Acetygen® would be a Minimal/Mild ocular irritant when tested at 3%.
Storage & Handling
- Shelf Life
- 18 Months
- Storage Condition
- DermalRx® Acetygen® should be stored at room temperature (18-25°C) in original packaging away from heat and light.