Knowde Enhanced TDS
Identification & Functionality
- Ingredient Origin
- Cosmetic Ingredients Functions
- Technologies
- Product Families
- Origin
- Holy Basil OSE is a proprietary extract of Ocimum sanctum that’s optimized for high concentrations of components with strong anti-inflammatory and skin-soothing activities.
Features & Benefits
- Benefit Claims
- Labeling Claims
- Benefits & Claims
- Plant-derived active produced from Holy Basil (Tulsi)
- Contains ursolic acid and other pentacyclic triterpenoids including betulinic acid and oleanolic acid
- Provides antioxidant activity against environmental stress
- Protects Extracellular Matrix via inhibition of proteolytic stress
- Modulates COX-2 activity
- Inhibits production of inflammatory mediators: IL-1α, IL-6, IL-8, TNF-α, MCP-1 and NF-κB
- Inhibits the inflammatory effects of urban air pollution
Applications & Uses
- Markets
- Skin Care Applications
- Sun Care Applications
- Use Level
- 0.5 - 2%
- Applications
- De-stressing anti-aging regimens targeting oxidative and proteolytic damage (pollution, UV exposure, etc.)
- Soothing and calming products for sensitive skin
- Formulas to treat mild-to-moderate blemishes in young and adult consumers
- Emulsions, creams and lotions
- Face and body oils
- Anhydrous color treatments
- Pre- and post-sun skin care
- Compatibility and Formulation
- Holy Basil OSE is not miscible in water but it can be added to a number of glycolic and oil systems (see miscibility chart). It is compatible with most conventional ingredients used in skin/hair care products. Add in the last step of formulation when temperature is below 50°C.
Regulatory & Compliance
- Certifications & Compliance
- Regulatory Information
- This product has not been tested on animals, and our company adheres to the written provisions of such animal rights organizations as Leaping Bunny and Cruelty/Free International.
- This product contains no animal products. It is manufactured using only plant based or synthetically derived (non-animal origin) materials and is thereby declared a Vegan Product.
- All materials used to produce this product are procured using sustainable sourcing practices.
- This product is manufactured in accordance with the current Good Manufacturing Practices (cGMP) requirements established by the U.S. Food and Drug Administration (FDA) for cosmetics. Furthermore, Biocogent, LLC, and this production facility(ies), are registered as cosmetic manufactures with the FDA.
- REACH compliance: All of the ingredients (substances) used in the manufacture of this product (mixture)are either registered under REACH, or qualify for an Article 2 (low volume of less than 1 metric ton), Annex IV or Annex V exemption, making our product REACH compliant.
- Proposition 65 compliance: Based upon Biocogent LLC’s knowledge of our business operations and chemical formulations, no chemicals listed by the State of California Environmental Protection Agency are used in our products, or as a processing aid for any product manufactured in our facility.
Technical Details & Test Data
- Test Data
Holy Basil OSE Inhibition of IL-6
Holy Basil OSE significantly reduced IL-6, a cytokine typically elevated with inflammation.
Holy Basil OSE Inhibition of DPM 2.5-Induced IL-1α
Holy Basil OSE dose-dependently reduced levels of IL-1α in the presence of diesel particulate matter (DPM).
Safety & Health
- Safety
- Human Repeat Insult Patch Testing (HRIPT) under semi-occlusive conditions indicated that Holy Basil OSE is not a primary skin irritant or a primary skin sensitizer when tested neat.
Storage & Handling
- Shelf Life
- 18 Months
- Storage Condition
- Holy Basil OSE should be stored at room temperature in original packaging away from heat and light.