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Pleiotanicals® Volpura® EPO (R10125)

Pleiotanicals® Volpura® EPO (R10125) is a plant-derived active ingredient extracted from Echinacea purpurea, known for its abundance in various active compounds, notably fatty acid alkylamides. This ingredient demonstrates the ability to activate PPAR-γ, which serves as the master regulator of adipogenesis. Its benefits lie in enhancing fat production by stimulating the differentiation of pre-adipocytes into adipocytes. This property makes it suitable for incorporation into formulations targeting anti-wrinkle effects, particularly for addressing expression lines in the forehead and nasolabial fold areas. Additionally, it finds application in facial contouring, re-firming, and plumping regimens aimed at addressing age-related lipoatrophy.

Brand: Pleiotanicals (9 products)

INCI Name: Caprylic/Capric Triglyceride, Echinacea Purpurea Extract, Squalane

Ingredient Origin: Natural Origin, Plant Origin

Labeling Claims: Naturally Derived, Plant-Based, Preservative-free

Benefit Claims: Anti-Aging, Anti-Inflammatory, Anti-Sagging, Anti-Wrinkle, Calming, Compatibility, Fine Lines Reduction, Firming, Formula Stability, Healthy-Looking Skin, Improves Skin Elasticity, Plumping, Promotes Youthful Skin, Reduces Crow’s Feet, Rejuvenating, Skin Strengthening Effect, Smooths Wrinkles, Soothing, Suitable for Sensitive Skin, Volumizing, Wrinkle Prevention, Wrinkle Refinement

Enhanced TDS

Enhanced TDS

Knowde-enriched technical product data sheet

Identification & Functionality

Cosmetic Ingredients Functions

Features & Benefits

Key Benefits

Benefit Claims:

  • Activates PPAR-γ, the master regulator of adipogenesis.
  • Increases fat production by stimulating pre-adipocyte differentiation into adipocytes.
  • Inhibits inflammation through the modulation of TNF-α and COX-2 activity.
  • Increased expression of six genes important for skin strength and health.

Clinical trial results showed:

  • Improvements of aging parameters in all three photographed areas: crow’s feet, nasolabial fold & forehead.
  • 44% increase in elasticity.
  • 14% increase in firmness.
  • Noticeable plumping effects on the face & back of the hands.
Compatibility Information
  • Volpura® EPO is compatible with most conventional ingredients used in skincare products.
  • Volpura® EPO has proven efficacy and stability in formulations requiring elevated temperatures up to 85°C for 6 hours.

Applications & Uses

Use Level
1 - 3 %
Applications
  • Volumizing and plumping formulas
  • Hot pour/hot cast products: Lipsticks, lip balms, lip glosses
  • Anti-wrinkle formulations for expression lines in the forehead and the nasolabial fold area
  • Facial contouring, re-firming, and plumping regimens to treat age-related lipoatrophy
  • Eye (peri-orbital lines) and lip contour products
  • Rejuvenating skin care products for neck and décolletage
  • Breast volumizing and buttocks sculpting formulations
  • Anti-aging hand creams
  • BB creams, CC creams, and color formulations
  • Soothing and calming for sensitive skin
  • Rejuvenating skin care products for neck and décolletage
  • Breast volumizing and buttocks sculpting formulations
  • Anti-aging hand creams
  • BB creams, CC creams, and color formulations
  • Soothing and calming for sensitive skin

Properties

Physical Form
Solubility
Appearance
Transparent liquid
Odor
Characteristic
Soluble in
Oil
Specifications
ValueUnitsTest Method / Conditions
Specific Gravity0.82 - 0.84--
Refractive Index1.44 - 1.46--

Technical Details & Test Data

Change in Appearance Comparison

Diminished appearance of facial wrinkles:

 - 2

Volpura® EPO is clinically proven to reduce the appearance of fine lines and wrinkles.

Heat Stability Comparison

Heat stability by alkylamide:

 - 1

Safety & Health

Safety Information
  • Human Repeat Insult Patch Testing (HRIPT) under semi-occlusive conditions indicated that Volpura® EPO is not a primary skin irritant or a primary skin sensitizer at recommended use levels.
  • Ocular irritation testing predicted that Volpura® EPO would be a Minimal ocular irritant at recommended use levels.

Storage & Handling

Shelf Life
12 months
Storage Conditions
  • Volpura® EP should be stored at room temperature in original packaging, protected from light.
  • Protect from extended cold storage and freezing.