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Harlem Bio Lab Sodium Acetylated Hyaluronate

Sodium Acetylated Hyaluronate (AcHA), is a specialty HA derivative which is synthesized from the Natural Moisturizing Factor Sodium Hyaluronate (HA) by acetylation reaction. The hydroxyl group of HA is partially replaced with acetyl group. It owns both lipophilic and hydrophilic properties. Sodium acetylated hyaluronate has the advantages of high skin affinity, efficient and lasting moisturizing, softening stratum corneum, strong skin softening, enhancing skin elasticity, improving skin roughness, etc. It is refreshing and non-greasy, and can be widely used in cosmetics such as lotion, mask and essence.

INCI Name: Sodium Acetylated Hyaluronate

Functions: Moisturizing Agent

Ingredient Origin: Fermentation

Labeling Claims: Allergen-free, Animal Products-free, BSE-free, CMR Substances-free, Clean at Sephora, Credo Clean Standard, GMO-free, Nanomaterials-free, Naturally Derived, Non-Carcinogenic, Not Listed In California Proposition 65, Not Tested on Animals, Odor-free, Palm Oil-free, Pesticide-free, SVHC Chemicals-free, TSE-free, Ulta Beauty's Conscious Beauty, Vegan

Certifications & Compliance: REACH Exempt (Europe)

Benefit Claims: Cell Regeneration, Easy To Handle, Hydrating, Improves Skin Elasticity, Long Lasting, Moist Feel, Moisture Retention, Moisturizing, Non-Greasy Feel, Penetrating, Refreshing, Repairing, Smoothing, Softening, Strengthening, Water Retention

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Knowde Enhanced TDS

Identification & Functionality

Ingredient Origin
Cosmetic Ingredients Functions

Features & Benefits

Functions of AcHA in Cosmetics
  • High Skin Affinity And Adsorption

Introduction of acetyl groups enhances the effectiveness of sodium hyaluronate . It owns both lipophilic and hydrophilic properties. AcHA can not only reduce water evaporation on the skin surface and increase internal water accumulation, but also penetrate into the epidermal hydration and soften the cuticle, so as to exert double moisturizing effect, improve the dry and rough state of the skin and make the skin soft and elastic.AcHA has excellent skin affinity, even after washing, can also be firmly adsorbed on the skin, play a lasting moisturizing, soft skin and other effects.

  • Superb Moisture Retention

AcHA can firmly adhere to the surface of the skin, reduce the loss of water on the surface of the skin, and increase the content of moisture of skin. It also can quickly penetrate into the stratum corneum, combine with the water in the stratum corneum, and hydrate to soften the stratum corneum. AcHA internal and external synergistic effect, play an efficient and lasting moisturizing effect, increase skin water content, improve skin rough, dry state, make skin full and moist.

  • Excellent In Improving Rough Skin

Since AcHA has both hydrophilic and hydrophobic properties, it has an exceptional affinity for the  stratum corneum, and can stay on the surface of the stratum corneum. Because of this unique character, more moisture evaporating from the stratum corneum is retained at the surface of the stratum corneum, resulting in an exceptional, long-lasting stratum corneum-softening effect. AcHA can promote cellular proliferation and repair damaged epidermal cells, thus strengthening the barrier function of stratum corneum, to effectively reduce water evaporation from inside, and improving the skin dryness and roughness.

  • Soften Stratum Corneum Effectively

AcHA has a special affinity to the stratum corneum, which can stay on the surface of the stratum corneum and produce a special and lasting softening effect of the stratum corneum, thus increasing the elasticity of the skin. After 4 weeks of continuous application of a facial cream containing AcHA, the skin elasticity of volunteers has significantly increased by 1.6 times and skin is softened.

Applications & Uses

Skin Care Applications
Use Level
0.01~0.1

Properties

Appearance
White powder and granules
Soluble in
water
Specifications
ValueUnitsTest Method / Conditions
pH6.0 - 7.5--
Inherent Viscosity19 - 26dl/g-
Puritymin. 93.0%HPLC
Light Transmittancemin. 99.0%-
Specific Rotation139 - 145°C-
Protein Contentmax. 0.05%-
Loss On Dryingmax. 8.0%-
Heavy Metal (Pb)max. 20ppm-
Total Bacteria Countmax. 10 cfu/g-
Yeast & Moldmax. 10 cfu/g-
StaphNegative--
Preudomonas AeruginosaNegative--
Sodium Chloride Contentmax. 0.5%-
Ethanol Contentmax. 0.05%-
Lead Contentmax. 20mg/kg-
Arsenic Contentmax. 2mg/kg-
Mercury Contentmax. 1mg/kg-
Cadmium Contentmax. 5mg/kg-
Acetyl Content23.8%-
Solubility
  • Soluble in alcohol-water mixture if the concentration of alcohol is below 50%
  • Limited solubility in alcohol-water mixture. Soluble in the mixture if the concentration of alcohol is more than 80%.

Regulatory & Compliance

Certifications & Compliance

Safety & Health

Safety

Avoid ingestion or direct contact by applying suitable protective measures and personal hygiene. For full safety information and necessary precaution, please refer to the respective Safety Data sheet.

Storage & Handling

Shelf Life
24.0
Stability and Storage
  • Storage: Store in originally sealed packaging in a cool and dry place.
  • Keep the package tightly closed. Once opened, use contents quickly. In order to avoid secondary microbial contamination, following opening containers should be handled with special care.