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Vazguard® is a standardized extract from Bergamot - Citrus bergamia Risso et Poiteau, exclusively sourced from a specific part of Southern Italy, in the Phytosome® form. It is effective thanks to the power of its unique mix of polyphenols and, in particular, a high concentration of flavonoids found in bergamot juice, albedo, and flavedo.

Ingredient Name: Bergamot Extract

Active Component: Flavonoids, Polyphenols

Functions: Phytochemical

Ingredient Origin: Natural Origin, Plant Origin

Labeling Claims: Naturally Derived, Plant-Based

Knowde Enhanced TDS

Identification & Functionality

Active Component
Ingredient Name
Pharma & Nutraceuticals Functions
Plant Source

Fruit juice

Features & Benefits

Product Overview
  • Citrus bergamia Risso et Poiteau, the scientific name of Bergamot, has been endemic in the Mediterranean area for several centuries and currently its production is limited to the Calabria region (Southern Italy).
  • Vazguard® is a standardized extract from Bergamot in Phytosome® formulation. Its BFC - Bergamot Polyphenolic Fraction - has shown to support health in case of challenges related to metabolic syndrome - sustained by inner abdominal fat - like high blood sugar, fatty liver, abnormal cholesterol or triglyceride levels, commonly associated to lack of physical activity, overweight, unhealthy diet and irregular life-style.
VAZGUARD® Features and Benefits
  • VAZGUARD® is the Bergamot Polyphenolic Fraction (BPF) formulated with Phytosome® delivery system (patent pending2) to optimize the biological absorption of polyphenols, which are normally characterized by poor solubility in both water and organic solvents.
  • The raw material is sourced only from a very small and specific part of the southern italian Calabria region, and Indena extensively characterized it from the phytochemical point of view: VAZGUARD® retains the same, unique phytochemical profile of the natural bergamot juice, its standardization in guaiacyl bioflavonoids is unique to Italian bergamot that outperforms all others Citrus flavonoids as antioxidants.
  • VAZGUARD® proved to be extremely effective in supporting health in case of challenges related to metabolic syndrome - sustained by inner abdominal fat - like high blood sugar, fatty liver, abnormal cholesterol or triglyceride levels, commonly associated to lack of physical activity, overweight, unhealthy diet and irregular life-style.
  • In a randomized, double-blind, placebo controlled human study, VAZGUARD®:
    • significantly optimize abdominal fat by -12% significant results could be observed within 1 month;
    • the optimization of abdominal fat translated into a global improvement of the glycolipidemic profile;
    • the LDL/HDL cholesterol was significantly optimized
    • exerted a significant beneficial effect on insulin resistence parameters (HOMA), thus suggesting a beneficial effect on appetite control;;the LDL/HDL cholesterol was significantly optimized
    • the supplementation also supported the normalization of liver function as reflected by transaminases levels.
  • In a recent investigation, VAZGUARD® showed potential efficacy in decreasing Firmicutes and Bacteroidetes, the intestinal microbiota associated with obesity, diabetes and cardiovascular risk.
Health Benefits

Abdominal fat shield, Cardiovascular Health, Healthy blood triglyceride levels, Healthy glucose metabolism, Triglycerides control

Applications & Uses

Food & Nutrition Applications
Use Level
500 mg/day (2x)

Properties

Physical Form
Appearance
Light yellow powder
Assay
ValueUnitsTest Method / Conditions
Total Flavanols14 - 18%HPLC Method

Technical Details & Test Data

Scientific Evidence

VAZGUARD® is supported by:

  • a human pharmacokinetics
  • a randomized double-blind, placebo controlled human efficacy study.
  • an investigation on intestinal microbiota
Vazguard® into Action
  • Vazguard® is effective thanks to the power of its unique mix of polyphenols and, in particular, thanks to a high concentration of flavonoids, found in bergamot juice, albedo and flavedo.
  • Specifically, Vazguard® is extremely good in supporting healthy blood levels through the optimization of total cholesterol, cLDL, cHDL, triglycerides, and glucose levels. With only 500 mg twice a day, equivalent to a full glass of Bergamot juice.
  • Furthermore, Vazguard® is the only bergamot ingredient with a scientific demonstration of activity on gut microflora.