Knowde Enhanced TDS
Identification & Functionality
- Ingredient Name
- Food Ingredients Functions
- Pharma & Nutraceuticals Functions
- Ingredients
- Lactobacillus Plantarums
Features & Benefits
- Benefit Claims (Health)
Applications & Uses
- Markets
- Food & Nutrition Applications
- Directions for Use
Only one tablet of CholBiome® must be taken once daily after the main meal for full health benefits.
- About the Gut-Liver Axis
The liver and the microorganisms of the gut microbiome have an intense functional and bidirectional communication known as the Gut-Liver Axis. In this metabolic cooperation, the liver produces and releases bile salts influencing cholesterol metabolism.
It is now known that certain microbes, such as LPLDL®, are able to metabolize bile salts, releasing metabolites that interact with the human body. This activity can help regulate high cholesterol and blood pressure and is involved in the regulation of physiological processes such as glucose regulation, vitamin metabolism and liver function.
- About Lactobacillus Plantarum LPLDL®
LPLDL® is a naturally-occurring strain of the bacterial species Lactobacillus plantarum. Lactobacilli are common components of the human intestinal microbiome and have traditionally been used as probiotics
.LPLDL® was selected using OptiBiotix’s OptiScreen® proprietary technology platform from a collection of over 4,000 microbial candidates for its outstanding capacity to hydrolyse bile salts. This activity is crucial for bacterial survival in the harsh conditions of the intestine and mediates LPLDL®’s mechanism of action.
An independent, double blind, randomized, placebocontrolled human study with LPLDL® was performed by the University of Reading (United Kingdom) with 50 hypercholesterolemic subjects, which were administered with a daily dose of 4x109 cfu of LPLDL® or placebo2. In the active group, LPLDL® showed to be completely safe and well tolerated and provide the following results